第791回 千葉医学会例会・第22回 麻酔科例会・第44回 千葉麻酔懇話会 9.

Correlations of plasma PIM-1 levels and clinicopathological parameters. (XLSX 11 kb

Additional file 2: of MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma

Figure S2. TFAP2C does not influence cell proliferation or the cell cycle. (A) TFAP2C overexpression in the AsPC-1 cell line had a trend of suppressing cell proliferation, but proliferation was not significantly different between the overexpressing cells and control cells. (B) TFAP2C knockdown in the T3M4 cell line had a trend of promoting cell proliferation, but proliferation was not significantly different between the knockdown cells and control cells. (C) TFAP2C overexpression in the AsPC-1 cell line had a trend of reducing the G1-S transition of the cell cycle, but this transition rate was not significantly different between the overexpressing cells and control cells. (D) TFAP2C knockdown in the T3M4 cell line had a trend of accelerating the G1-S transition of the cell cycle, but this transition rate was not significantly different between the knockdown cells and control cells. The data are presented as the means ± SD (Student’s t-test; *, P < 0.05). (PNG 406 kb

Additional file 1: of MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma

Figure S1. MiR-10a-5p does not influence cell proliferation, cell apoptosis or the cell cycle. (A) MiR-10a-5p overexpression in the T3M4 cell line had a trend of promoting cell proliferation, but proliferation was not significantly different between the overexpressing cells and control cells. (B) MiR-10a-5p overexpression in the T3M4 cell line had a trend of decreasing gemcitabine-induced cell apoptosis, but apoptosis was not significantly different between the overexpressing cells and control cells. (C) MiR-10a-5p knockdown in the Su86.86 cell line had a trend of suppressing cell proliferation, but proliferation was not significantly different between the knockdown cells and control cells. (D) MiR-10a-5p knockdown in the Su86.86 cell line had a trend of promoting gemcitabine-induced cell apoptosis, but apoptosis was not significantly different between the knockdown cells and control cells. (E) MiR-10a-5p overexpression in the T3M4 cell line had a trend of accelerating the S-G2 transition of the cell cycle, but this transition rate was not significantly different between the overexpressing cells and control cells. (F) MiR-10a-5p knockdown in the Su86.86 cell line reduced the S-G2 transition of the cell cycle. The data are presented as the means ± SD (Student’s t-test; *, P < 0.05). (PNG 994 kb

Additional file 3: Table S2. of PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value

Univariate and multivariable analyses of factors predictive of poor overall survival in patients with pancreatic cancer (tissues). (XLSX 12 kb