Effects of Bushenyiqihexue Formula on the Endometrial Gland Apoptosis in Mice with Blastocyst Implantation Dysfunction

ObjectiveTo observe the effects of Bushenyiqihexue Formula (Formula for Tonifying the Kidney, Replenishing qi and Harmonizing Blood, FTKRQHB) on the endometrial gland apoptosis in the mice with blastocyst implantation dysfunction.MethodsThe mice with the first-day pregnancy were divided into the control, model and treatment groups, with 30 in each group, and blastocyst implantation dysfunction was induced by subcutaneous injection of mifepristone in the mice of the model and treatment groups. The pregnancy rate and implantation number of blastocysts were measured and the expressions of proliferating cell nuclear antigen (PCNA), Bax, Bcl-2, and activated caspase-3 were detected in all the three groups.ResultsThe model group had significantly depressed pregnancy rate, implantation number of blastocysts and apoptosis index, and elevated proliferation index of endometrial gland as compared with the control group (P<0.05 or P<0.01). Administration of FTKRQHB (the treatment group) resulted in significant increases in pregnancy rate, implantation number of blastocysts and apoptosis index of the endometrial gland, and a significant decrease in the proliferation index of the endometrial gland as compared with the model group (P<0.05 or P<0.01). The differences in the four indexes between the treatment group and control group were not significant statistically. The Bax and activated caspase-3 expressions in endometrial gland in the model group became significantly lower than that of the control group (P<0.01), whereas those in the treatment group were significant higher than that of the model group (P<0.01). However, the Bax and activated caspase-3 expressions in endometrial gland were similar in both treatment and control groups.ConclusionPromoting the increases in Bax and activated caspase-3 expressions in the endometrial gland and bringing into balance between apoptosis and proliferation of the glandular cells at the implantation window phase by FTKRQHB may contribute to the effects of promoting the establishment of endometrial receptivity and improving blastocyst implantation dysfunction

Anisotropic Pauli spin-blockade effect and spin-orbit interaction field in an InAs nanowire double quantum dot

We report on experimental detection of the spin-orbit interaction field in an InAs nanowire double quantum dot device. In the spin blockade regime, leakage current through the double quantum dot is measured and is used to extract the effects of spin-orbit interaction and hyperfine interaction on spin state mixing. At finite magnetic fields, the leakage current arising from the hyperfine interaction is suppressed and the spin-orbit interaction dominates spin state mixing. We observe dependence of the leakage current on the applied magnetic field direction and determine the direction of the spin-orbit interaction field. We show that the spin-orbit field lies in a direction perpendicular to the nanowire axis but with a pronounced off-substrate-plane angle. It is for the first time that such an off-substrate-plane spin-orbit field in an InAs nanowire has been detected. The results are expected to have an important implication in employing InAs nanowires to construct spin-orbit qubits and topological quantum devices.Comment: 20 pages, 5 figures, Supporting Informatio

(E)-(2,4-Dichloro­phen­yl)[2-hydr­oxy-6-(methoxy­imino)cyclo­hex-1-en­yl]methanone

The title compound, C14H13Cl2NO3, was obtained as the product of an attempted synthesis of herbicidally active compounds containing oxime ether and cyclo­hexenone groups. In the crystal structure, the mol­ecule adopts an endocyclic enol tautomeric form and the cyclo­hexene ring adopts a distorted envelope form. The oxime ether group has an E configuration, with the meth­oxy group anti to the ortho-chloro substitutent. Intra­molecular O—H⋯O and inter­molecular C—H⋯O hydrogen bonds are found in the crystal structure

Dependence of the decoherence of polarization states in phase-damping channels on the frequency spectrum envelope of photons

We consider the decoherence of photons suffering in phase-damping channels. By exploring the evolutions of single-photon polarization states and two-photon polarization-entangled states, we find that different frequency spectrum envelopes of photons induce different decoherence processes. A white frequency spectrum can lead the decoherence to an ideal Markovian process. Some color frequency spectrums can induce asymptotical decoherence, while, some other color frequency spectrums can make coherence vanish periodically with variable revival amplitudes. These behaviors result from the non-Markovian effects on the decoherence process, which may give rise to a revival of coherence after complete decoherence.Comment: 7 pages, 4 figures, new results added, replaced by accepted versio

Space-time dual quantum Zeno effect: Interferometric engineering of open quantum system dynamics

Superposition of trajectories, which modify quantum evolutions by superposing paths through interferometry, has been utilized to enhance various quantum communication tasks. However, little is known about its impact from the viewpoint of open quantum systems. Thus, we examine this subject from the perspective of system-environment interactions. We show that the superposition of multiple trajectories can result in quantum state freezing, suggesting a space-time dual to the quantum Zeno effect. Moreover, non-trivial Dicke-like super(sub)radiance can be triggered without utilizing multi-atom correlations.Comment: 12 pages and 4 figure