1,705 research outputs found

    A Taxonomy of Hyperlink Hiding Techniques

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    Hidden links are designed solely for search engines rather than visitors. To get high search engine rankings, link hiding techniques are usually used for the profitability of black industries, such as illicit game servers, false medical services, illegal gambling, and less attractive high-profit industry, etc. This paper investigates hyperlink hiding techniques on the Web, and gives a detailed taxonomy. We believe the taxonomy can help develop appropriate countermeasures. Study on 5,583,451 Chinese sites' home pages indicate that link hidden techniques are very prevalent on the Web. We also tried to explore the attitude of Google towards link hiding spam by analyzing the PageRank values of relative links. The results show that more should be done to punish the hidden link spam.Comment: 12 pages, 2 figure

    Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian

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    Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China. 

Methods: Allele-specific PCR and a multiplex PCR were employed to identify the genotypes of I462V of CYP1A1 and GSTM1 in a case-control study of 210 lung cancer patients with bronchoscopy diagnosis and 210 matched controls free of malignancy.

Results: The frequencies of the variant CYP1A1(Val/Val) genotypes and GSTM1(-) in lung cancer groups were higher than that in control groups (15.24% vs 7.4% and 56.67% vs 40.95% ). The individuals who carried with CYP1A1(Val/Val) or GSTM1(-) genotype had a significantly higher risk of lung cancer, the OR is 2.56 and 1.89 respectively. Stratified histologically the relative risk increased to 2.6 - fold when the patients carried with two valine alleles than the ones carried one valine allele in cases of SCC. GSTM1(-) genotype is the risk factor of SCC (OR=2.39) and AC(OR=2.16). The presence of at least one Val allele of CYP1A1 and GSTM1(-), the risk of lung cancer was increased, the OR was 4.15 for one Val allele and GSTM1(-) and 2.67 for two Val alleles and GSTM1 Considering ages and smoking status, the risk of lung cancer increased when the age less than 50 who carried with CYP1A1 valine (one or two) alleles or the age during the 51 to 65 who carried with GSTM1(-) genotype. The light smokers with CYP1A1 valine alleles and GSTM1(-) have a high risk for lung cancer. No association was found between the light and heavy drinkers with the susceptibility of lung cancer and the genetic polymorphisms of CYP1A1 I462V and GSTM1(-). 

Conclusion: The valine allele of CYP1A1 was the risk factors of lung cancer especially for SCC and GSTM1(-) also was the risk factor of lung cancer and especially for SCC and AC of Mongolian, China. Light smoking has a influence each other with genotype of CYP1A1 I462V and GSTM1(-) and susceptibility of lung cancer. No relationship was found between the susceptibility of lung cancer and drinkers with genetic polymorphisms of CYP1A1 I462V and GSTM1(-). The influence of genotypes on the susceptibility of lung cancer may depend on the ages. There may be a synergetic interaction between CYP1A1 valine allele and GSTM1(-) genotypes on the elevated susceptibility of lung cancer. So do those genotypes with light smokers. Key words polymorphism; genotype; lung cancer; cytochrome P450;glutathione S-transferase Abbreviations: SCC, squamous cell carcinoma; AC, adenocarcinoma; SCLC, small cell lung cancer; LCLC, large cell lung cance

    Studies on cold hardiness of grapevine roots

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    For 16 grapevine rootstocks, the critical chilling temperatures were determined. There were great differences in cold hardiness among these vines. The cold hardiness öf several newly introduced rootstocks was higher than that of rootstock variety Beta and they showed even multiple resistance. Thus, after further testing experiments, they might become valuable rootstocks in cold regions.There were some differences in cold hardiness among 3 fruiting varieties tested. This finding can be used as reference in formulating winter protection measures for own-rooted grapes.Comparative examination of the methods for testing cold hardiness showed that the combination of electrolytic conductance method with root section culture was simple and reliable for measuring cold hardiness of grape roots, while TTC reduction method, because of its Jack of regularity in test results, was not suitable for this purpose.The characteristics of root structure have certain correlations with cold hardiness: (i) Varieties with higher cold hardiness have smaller hark and ray cells than tender varieties and their tissue structure is more compact. (ii) Vessel diameter is smaller and vessel density is lower in hardy varieties. (iii) Varieties with higher cold h ardiness have a lower percentage of hark and a higher rate of xylem in their roots.Thus, these characteristics of root structure could be used as an additional index in forecasting and screening cold hardiness of grape roots

    A multi-wavelength observation and investigation of six infrared dark clouds

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    Context. Infrared dark clouds (IRDCs) are ubiquitous in the Milky Way, yet they play a crucial role in breeding newly-formed stars. Aims. With the aim of further understanding the dynamics, chemistry, and evolution of IRDCs, we carried out multi-wavelength observations on a small sample. Methods. We performed new observations with the IRAM 30 m and CSO 10.4 m telescopes, with tracers HCO+{\rm HCO^+}, HCN, N2H+{\rm N_2H^+}, C18O{\rm C^{18}O}, DCO+^+, SiO, and DCN toward six IRDCs G031.97+00.07, G033.69-00.01, G034.43+00.24, G035.39-00.33, G038.95-00.47, and G053.11+00.05. Results. We investigated 44 cores including 37 cores reported in previous work and seven newly-identified cores. Toward the dense cores, we detected 6 DCO+^+, and 5 DCN lines. Using pixel-by-pixel spectral energy distribution (SED) fits of the Herschel\textit{Herschel} 70 to 500 μ\mum, we obtained dust temperature and column density distributions of the IRDCs. We found that N2H+{\rm N_2H^+} emission has a strong correlation with the dust temperature and column density distributions, while C18O{\rm C^{18}O} showed the weakest correlation. It is suggested that N2H+{\rm N_2H^+} is indeed a good tracer in very dense conditions, but C18O{\rm C^{18}O} is an unreliable one, as it has a relatively low critical density and is vulnerable to freezing-out onto the surface of cold dust grains. The dynamics within IRDCs are active, with infall, outflow, and collapse; the spectra are abundant especially in deuterium species. Conclusions. We observe many blueshifted and redshifted profiles, respectively, with HCO+{\rm HCO^+} and C18O{\rm C^{18}O} toward the same core. This case can be well explained by model "envelope expansion with core collapse (EECC)".Comment: 24 pages, 11 figures, 4 tables. To be published in A&A. The resolutions of the pictures are cut dow
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