Spatial pattern of the time evolution at different instants.

<p>Snapshots of contour pictures of the time evolution of CML system at some instants with <i>λ</i> = 2.9 and <i>ε</i> = 0.34 in the Turing instability region. (A) <i>t</i> = 0. (B) <i>t</i> = 100. (C) <i>t</i> = 5000. (D) <i>t</i> = 10000. (E) <i>t</i> = 50000. (F) <i>t</i> = 100000.</p

Spatial pattern of the time evolution at different instants.

<p>Snapshots of contour pictures of the time evolution of CML system at some instants with <i>λ</i> = 1.5 and <i>ε</i> = 0.4 in the Turing instability region. (A) <i>t</i> = 0. (B) <i>t</i> = 57. (C) <i>t</i> = 69.</p

Effect of an Auxiliary Plate on Passive Heat Dissipation of Carbon Nanotube-Based Materials

Carbon nanotubes (CNTs) and other related CNT-based materials with a high thermal conductivity can be used as promising heat dissipation materials. Meanwhile, the miniaturization and high functionality of portable electronics, such as laptops and mobile phones, are achieved at the cost of overheating the high power-density components. The heat removal for hot spots occurring in a relatively narrow space requires simple and effective cooling methods. Here, an auxiliary passive cooling approach by the aid of a flat plate (aluminum–magnesium alloy) is investigated to accommodate heat dissipation in a narrow space. The cooling efficiency can be raised to 43.5%. The cooling performance of several CNT-based samples is compared under such circumstances. Heat dissipation analyses show that, when there is a nearby plate for cooling assistance, the heat radiation is weakened and natural convection is largely improved. Thus, improving heat radiation by increasing emissivity without reducing natural convection can effectively enhance the cooling performance. Moreover, the decoration of an auxiliary cooling plate with sprayed CNTs can further improve the cooling performance of the entire setup

Phenothiazine-Based 2D Covalent Organic Framework for Efficient Visible-Light-Induced Free Radical Polymerization

Phenothiazine derivatives have attracted tremendous research attention due to their rich redox-active properties. In this work, a phenothiazine-based, highly crystalline, and two-dimensional covalent organic framework (PTz-An-COF) was developed. PTz-An-COF exhibited a low bandgap of 1.92 eV with a broad visible-light absorption. Interestingly, PTz-An-COF can serve as an efficient photoinitiator for visible-light-induced radical polymerization of methyl acrylate. Remarkably, PTz-An-COF as a photoinitiator can be easily recycled and maintains the same catalytic activity as that of pristine PTz-An-COF. This work provides new insights into the development of high-performance heterogeneous photocatalysts for radical polymerization

Identification of pathogen composition in a Chinese population with iatrogenic and native vertebral osteomyelitis by using mNGS

Early antimicrobial therapy is crucial regarding the prognosis of vertebral osteomyelitis, but early pathogen diagnosis remains challenging. In this study, we aimed to differentiate the types of pathogens in iatrogenic vertebral osteomyelitis (IVO) and native vertebral osteomyelitis (NVO) to guide early antibiotic treatment. A total of 145 patients, who had confirmed spinal infection and underwent metagenomic next-generation sequencing (mNGS) testing, were included, with 114 in the NVO group and 31 in the IVO group. Using mNGS, we detected and classified 53 pathogens in the 31 patients in the IVO group and 169 pathogens in the 114 patients in the NVO group. To further distinguish IVO from NVO, we employed machine learning algorithms to select serum biomarkers and developed a nomogram model. The results revealed that the proportion of the Actinobacteria phylum in the NVO group was approximately 28.40%, which was significantly higher than the 15.09% in the IVO group. Conversely, the proportion of the Firmicutes phylum (39.62%) in the IVO group was markedly increased compared to the 21.30% in the NVO group. Further genus-level classification demonstrated that Staphylococcus was the most common pathogen in the IVO group, whereas Mycobacterium was predominant in the NVO group. Through LASSO regression and random forest algorithms, we identified 5 serum biomarkers including percentage of basophils (BASO%), percentage of monocytes (Mono%), platelet volume (PCT), globulin (G), activated partial thromboplastin time (APTT) for distinguishing IVO from NVO. Based on these biomarkers, we established a nomogram model capable of accurately discriminating between the two conditions. The results of this study hold promise in providing valuable guidance to clinical practitioners for the differential diagnosis and early antimicrobial treatment of vertebral osteomyelitis.</p

MOESM2 of A new insight into the role of plasma fibrinogen in the development of metabolic syndrome from a prospective cohort study in urban Han Chinese population

Additional file 2: Table S1. Baseline characteristics of participants grouped by fibrinogen quartiles

Insight into the Spectrum of Coronary Atherosclerosis in Asymptomatic Urban Han Chinese Population by Coronary Computed Tomography Angiography

<div><p>Objectives</p><p>Highlighted the spectrum of coronary atherosclerosis in asymptomatic population by Computed Tomography Angiography (CTA) and developed a surrogation of expensive CTA to early detect coronary atherosclerosis.</p><p>Methods</p><p>Three hundred and seven self-referred urban Han Chinese asymptomatic individuals underwent coronary CTA were consecutively enrolled. Total plaque score (TPS), Segment stenosis score (SSS) and Coronary Artery Disease severity (CADS) were used to measure and illustrate the spectrum of atherosclerosis burden by mapping their incidence and proportion onto coronary artery tree. Logistic regression model was further used to explore the association between lipid biomarkers and TPS (SSS) for developing a surrogation of CTA to early detect coronary atherosclerosis.</p><p>Results</p><p>We found that the incidence of TPS, SSS and CADS were up to 71.34%, 68.08%, and 71.34%; and high-risk individuals reached up to 11.07%, 15.31% and 16.29% respectively. All TPS, SSS and CADS were much higher in male than female, and have trend of increasing with age. The most lesion segment emerged on proximal LAD, followed by proximal RCA, mid LAD, proximal LCX, and mid RCA with mixed plaque as dominant. HDL-C was a predictor to both TPS [OR: 0.12 (0.02–0.82)] and SSS [OR: 0.15 (0.03–0.76)], and could identify the serious atherosclerosis subjects of TPS or SSS score >5 (AUC 0.73 and 0.70).</p><p>Conclusions</p><p>The atherosclerosis plaque burden was about one in ten as high-risk individuals in this specific urban Han Chinese population. As potential surrogation of CTA, HDL-C was recognized as a significant predictor to atherosclerosis burden and revealed a good performance for identifying high-risk individuals.</p></div

MOESM1 of A new insight into the role of plasma fibrinogen in the development of metabolic syndrome from a prospective cohort study in urban Han Chinese population

Additional file 1: Figure S1. The framework of original cohort

The spectrum of atherosclerosis burden in each segment of coronary artery tree.

<p>The coronary artery tree was classified into 16 segments according to American Heart Association classification 1] proximal, 2] mid, 3] distal right coronary artery; 4] posterior descending artery; 5] left main artery; 6] proximal, 7] mid, 8] distal left anterior descending artery; 9] first, 10] second diagononal branch; 11] proximal, 13] mid, 15] distal left circumflex artery; 12] first, 14] second obtuse marginal branch; 16] posterolateral ventricular branch]. The degree of stenosis and composition of plaque of each segment was evaluated. The incidence of plaque and proportion of plaque (CP, MP, NCP) were noted on each segment in fig 2 (top). The degree of stenosis of each segment was classicized into four groups: 0 for normal, 1 for <50%,2 for 50% to 69%, 3 for ≥70% and their proportion were recorded in fig 2 (lower). CP = calcified plaques. MP = mixed plaques. NCP = non-calcified plaques.</p

High-Performance Organic Small-Molecule Panchromatic Photodetectors

High-performance panchromatic organic photodetectors (OPDs) containing small molecules lead phthalocyanine (PbPc) and C₇₀ fullerene as donor and acceptor, respectively, were demonstrated. The OPDs had either a PbPc/C₇₀ planar heterojunction (PHJ) or a PbPc/PbPc:C₇₀/C₇₀ hybrid planar-mixed molecular heterojunction (PM-HJ) structure. Both the PHJ and the PM-HJ devices showed a broad-band response that covered wavelengths from 300 to 1100 nm. An external quantum efficiency (EQE) higher than 10% and detectivity on the order of 10¹² Jones were obtained in the wavelength region from 400 to 900 nm for the PHJ device. The EQE in the near-infrared region was enhanced by using the PM-HJ device structure, and a maximum EQE of 30.2% at 890 nm was observed for the optimized device with a 5% PbPc-doped C₇₀ layer. Such an EQE is the highest at this wavelength of reported OPDs. The detectivity of the PM-HJ devices was also higher than that of the PHJ one, which is attributed to the increased efficiency of exciton dissociation in bulk heterojunction structure, increased absorption efficiency caused by formation of triclinic PbPc in the PbPc:C₇₀ mixed film when it was deposited on a pristine PbPc layer, and high hole mobility of the PbPc-doped C₇₀ layer