9,141 research outputs found

    Promotion of cooperation induced by nonlinear attractive effect in spatial Prisoner's Dilemma game

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    We introduce nonlinear attractive effects into a spatial Prisoner's Dilemma game where the players located on a square lattice can either cooperate with their nearest neighbors or defect. In every generation, each player updates its strategy by firstly choosing one of the neighbors with a probability proportional to Aα\mathcal{A}^\alpha denoting the attractiveness of the neighbor, where A\mathcal{A} is the payoff collected by it and α\alpha (\geq0) is a free parameter characterizing the extent of the nonlinear effect; and then adopting its strategy with a probability dependent on their payoff difference. Using Monte Carlo simulations, we investigate the density ρC\rho_C of cooperators in the stationary state for different values of α\alpha. It is shown that the introduction of such attractive effect remarkably promotes the emergence and persistence of cooperation over a wide range of the temptation to defect. In particular, for large values of α\alpha, i.e., strong nonlinear attractive effects, the system exhibits two absorbing states (all cooperators or all defectors) separated by an active state (coexistence of cooperators and defectors) when varying the temptation to defect. In the critical region where ρC\rho_C goes to zero, the extinction behavior is power law-like ρC\rho_C \sim (bcb)β(b_c-b)^{\beta}, where the exponent β\beta accords approximatively with the critical exponent (β0.584\beta\approx0.584) of the two-dimensional directed percolation and depends weakly on the value of α\alpha.Comment: 7 pages, 4 figure

    KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation.

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    KDM2B (also known as FBXL10) controls stem cell self-renewal, somatic cell reprogramming and senescence, and tumorigenesis. KDM2B contains multiple functional domains, including a JmjC domain that catalyzes H3K36 demethylation and a CxxC zinc-finger that recognizes CpG islands and recruits the polycomb repressive complex 1. Here, we report that KDM2B, via its F-box domain, functions as a subunit of the CUL1-RING ubiquitin ligase (CRL1/SCF(KDM2B)) complex. KDM2B targets c-Fos for polyubiquitylation and regulates c-Fos protein levels. Unlike the phosphorylation of other SCF (SKP1-CUL1-F-box)/CRL1 substrates that promotes substrates binding to F-box, epidermal growth factor (EGF)-induced c-Fos S374 phosphorylation dissociates c-Fos from KDM2B and stabilizes c-Fos protein. Non-phosphorylatable and phosphomimetic mutations at S374 result in c-Fos protein which cannot be induced by EGF or accumulates constitutively and lead to decreased or increased cell proliferation, respectively. Multiple tumor-derived KDM2B mutations impaired the function of KDM2B to target c-Fos degradation and to suppress cell proliferation. These results reveal a novel function of KDM2B in the negative regulation of cell proliferation by assembling an E3 ligase to targeting c-Fos protein degradation that is antagonized by mitogenic stimulations

    Promote cooperation by localised small-world communication

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    The emergence and maintenance of cooperation within sizable groups of unrelated humans offer many challenges for our understanding. We propose that the humans' capacity of communication, such as how many and how far away the fellows can build up mutual communications, may affect the evolution of cooperation. We study this issue by means of the public goods game (PGG) with a two-layered network of contacts. Players obtain payoffs from five-person public goods interactions on a square lattice (the interaction layer). Also, they update strategies after communicating with neighbours in learning layer, where two players build up mutual communication with a power law probability depending on their spatial distance. Our simulation results indicate that the evolution of cooperation is indeed sensitive to how players choose others to communicate with, including the amount as well as the locations. The tendency of localised communication is proved to be a new mechanism to promote cooperation.Comment: 6 pages, 4 figure

    Jordan-Wigner fermionization for the one-dimensional Bariev model of three coupled XY chains

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    The Jordan-Wigner fermionization for the one-dimensional Bariev model of three coupled XY chains is formulated. The Lax operator in terms of fermion operators and the quantum R-matrix are presented explicitly. Furthermore, the graded reflection equations and their solutions are discussed.Comment: 10 pages, no figur

    Random walks on the Apollonian network with a single trap

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    Explicit determination of the mean first-passage time (MFPT) for trapping problem on complex media is a theoretical challenge. In this paper, we study random walks on the Apollonian network with a trap fixed at a given hub node (i.e. node with the highest degree), which are simultaneously scale-free and small-world. We obtain the precise analytic expression for the MFPT that is confirmed by direct numerical calculations. In the large system size limit, the MFPT approximately grows as a power-law function of the number of nodes, with the exponent much less than 1, which is significantly different from the scaling for some regular networks or fractals, such as regular lattices, Sierpinski fractals, T-graph, and complete graphs. The Apollonian network is the most efficient configuration for transport by diffusion among all previously studied structure.Comment: Definitive version accepted for publication in EPL (Europhysics Letters

    Continuous twin screw rheo-extrusion of an AZ91D magnesium alloy

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    © The Minerals, Metals & Materials Society and ASM International 2012The twin screw rheo-extrusion (TSRE) is designed to take advantage of the nondendritc microstructure and thixotropic characterization of semisolid-metal slurries and produce simple metal profiles directly from melts. The extrusion equipment consists of a rotor-stator high shear slurry maker, a twin screw extruder, and a die assembly. The process is continuous and has a potential for significantly saving energy, manufacturing cost, and enhancing efficiency. The present investigation was carried out to study the process performance for processing rods of an AZ91D magnesium alloy and the microstructure evolution during processing. The semisolid slurry prepared by the process was characterized by uniformly distributed nondendritic granular primary phase particles. AZ91D rods with uniform and fine microstructures and moderate mechanical properties were produced. For the given slurry making parameters, decreasing extrusion temperature was found to improve microstructures and properties. The mechanisms of particle granulation and refinement and the effect of processing parameters on process performance and thermal management are discussed. © 2012 The Minerals, Metals & Materials Society and ASM International.EPSRC (UK) and Rautomead Lt

    On the equivalence of Eulerian and Lagrangian variables for the two-component Camassa-Holm system

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    The Camassa-Holm equation and its two-component Camassa-Holm system generalization both experience wave breaking in finite time. To analyze this, and to obtain solutions past wave breaking, it is common to reformulate the original equation given in Eulerian coordinates, into a system of ordinary differential equations in Lagrangian coordinates. It is of considerable interest to study the stability of solutions and how this is manifested in Eulerian and Lagrangian variables. We identify criteria of convergence, such that convergence in Eulerian coordinates is equivalent to convergence in Lagrangian coordinates. In addition, we show how one can approximate global conservative solutions of the scalar Camassa-Holm equation by smooth solutions of the two-component Camassa-Holm system that do not experience wave breaking

    Nanometallic Glasses: Size Reduction Brings Ductility, Surface State Drives Its Extent

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    We report tensile experiments on Ni_(80)P_20 metallic glass samples fabricated via a templated electroplating process and via focused ion beam milling, which differed only in their surface energy states: Ga-ion-irradiated and as-electroplated. Molecular dynamics simulations on similar Ni_(80)Al_20 systems corroborate the experimental results, which suggest that the transition from brittle to ductile behavior is driven by sample size, while the extent of ductility is driven by surface state
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