6 research outputs found
The temporal effects of typical and atypical antipsychotic drugs
- Author
- Publication venue
- Publication date
- 01/01/1998
- Field of study
No full textSIGLEAvailable from British Library Document Supply Centre-DSC:DXN027933 / BLDSC - British Library Document Supply CentreGBUnited Kingdo
α 2-Adrenoreceptor antagonism may contribute to the atypical properties of risperidone: experimental support for the Nutt case
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
No full textContext-induced relapse to drug seeking: a review
- Author
- Publication venue
- 'The Royal Society'
- Publication date
- 12/10/2008
- Field of study
No full textIn humans, exposure to environmental contexts previously associated with drug intake often provokes relapse to drug use, but the mechanisms mediating this relapse are unknown. Based on early studies by Bouton & Bolles on context-induced `renewal of learned behaviours, we developed a procedure to study context-induced relapse to drug seeking. In this procedure, rats are first trained to self-administer drug in one context. Next, drug-reinforced lever responding is extinguished in a different (non-drug) context. Subsequently, context-induced reinstatement of drug seeking is assessed by re-exposing rats to the drug-associated context. Using variations of this procedure, we and others reported reliable context-induced reinstatement in rats with a history of heroin, cocaine, heroincocaine combination, alcohol and nicotine self-administration. Here, we first discuss potential psychological mechanisms of context-induced reinstatement, including excitatory and inhibitory Pavlovian conditioning, and occasion setting. We then summarize results from pharmacological and neuroanatomical studies on the role of several neurotransmitter systems (dopamine, glutamate, serotonin and opioids) and brain areas (ventral tegmental area, accumbens shell, dorsal striatum, basolateral amygdala, prefrontal cortex, dorsal hippocampus and lateral hypothalamus) in context-induced reinstatement. We conclude by discussing the clinical implications of rat studies on context-induced reinstatement of drug seeking
Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set-shifting
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
No full textTargeting the 5-HT2C Receptor in Biological Context and the Current State of 5-HT2C Receptor Ligand Development
- Author
- Anastasio N.C.
- Anastasio N.C.
- Anastasio N.C.
- Anastasio N.C.
- Berg K.A.
- Berg K.A.
- Besson M.
- Bigford G.E.
- Boger D.L.
- Boger D.L.
- Bohn L.M.
- Bridges T.M.
- Bubar M.J.
- Bubar M.J.
- Bubar M.J.
- Bubar M.J.
- Burke J.E.
- Bös M.
- Carpenter J.
- Cheer J.F.
- Chen C.X.
- Cheng J.
- Cheng J.
- Christopher T. Wild
- Christopoulos A.
- Christopoulos A.
- Conn P.J.
- Conn P.J.
- Connolly H.M.
- Cunningham K.A.
- Cunningham K.A.
- Cunningham K.A.
- Di Giovanni G.
- Di Giovanni G.
- Di Giovanni G.
- Ding C.
- Dror R.O.
- Dunlop J.
- Dunlop J.
- Eric A. Wold
- Everitt B.J.
- Farr O.M.
- Fedorova I.
- Felsing D.E.
- Felsing D.E.
- Fevig J.M.
- Fitzgerald L.W.
- Fitzgerald L.W.
- Fletcher P.J.
- Fletcher P.J.
- Foster D.J.
- GarcÃa-Cárceles J.
- Gautron L.
- Ge T.
- Gobert A.
- Greenway F.L.
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- Heifetz A.
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- Higgins G.A.
- Howell L.L.
- Hoy S.M.
- Huidobro-Toro J.P.
- Im W.B.
- Jia Zhou
- Kalgutkar A.S.
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- SpÃzek J.
- Storer R.I.
- Sugiura T.
- Swinford-Jackson S.E.
- Tecott L.H.
- Theile J.W.
- Thomas E.A.
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- Wirshing D.A.
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- Wootten D.
- Xu P.
- Zhang G.
- Zhao G.
- Zhou J.
- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study
No full textNeurochemistry of Drug Abuse
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- Acri J.
- Aghajanian G.K.
- Akiyama K.
- Akiyama K.
- Alburges M.
- Alburges M.E.
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- O'Halloran R.L.
- O'Hearn E.
- O'Malley S.S.
- O'Shea E.
- Ochoa E.
- Okuyama S.
- Olausson P.
- Olausson P.
- Olausson P.
- Omelchenko N.
- Ouimet C.C.
- Ouimet C.C.
- Palmatier M.I.
- Pan G.
- Pandey S.C
- Pandey S.C.
- Parker S.L.
- Parrott A.C.
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- Parsons L.H.
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- Paterson N.E.
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- Pearl S.
- Peng X.
- Pennartz C.M.
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- Peris J.
- Perkins K.A.
- Perry D.
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- Picciotto M.R.
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- Pietila K.
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- Poland R.E.
- Poland R.E.
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- Pristupa Z.B.
- Przewlocka B.
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- Pögün S.
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- Racke K.
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- Ranaldi R.
- Rapier C.
- Rasmussen K.C.J
- Rausch J.
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- Raynor K.
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- Reith M.
- Reith M.
- Reith M.E.A.
- Reith M.E.A.
- Reith M.E.A.
- Reneman L.
- Ricaurte G.A.
- Ricaurte G.A.
- Ricaurte G.A.
- Ricaurte G.A.
- Ricaurte G.A.
- Rice M.E.
- Richardson N.
- Riddle E.L.
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- Ritz M.
- Ritz M.C.
- Ritz M.C.
- Ritz M.C.
- Robbins T.W.
- Robbins T.W.
- Roberts D.
- Roberts D.
- Roberts D.C
- Roberts D.C.
- Roberts D.C.
- Roberts D.C.
- Robertson G.S.
- Robinson D.L.
- Robinson T.E.
- Robinson T.E.
- Robinson T.E.
- Robinson T.E.
- Robinson T.E.
- Robinson T.E.
- Robinson T.E.
- Robinson T.E.
- Robinson T.E.
- Robledo P.
- Rocha B.A.
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- Rocher C.
- Rocio M.
- Rocio M.
- Rockhold R.
- Rockhold R.W
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- Rommelspacher H.
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- Rostene W.
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- Rothman R.
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- Rothman R.B.
- Rothman R.B.
- Rudnick G.
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- Russell V.A.
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- Saal D.
- Sabol S.Z.
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- Satel S.L.
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- Scanzello C.R.
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- Scheffel U.
- Scheffel U.
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- Schenk S.
- Schenk S.
- Schenk S.
- Schenk S.
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- Schifano F.
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- Schilstrom B.
- Schmidt C.J.
- Schmidt C.J.
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- Schmidt C.J.
- Schmidt C.J.
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- Schneider N.G.O.R.
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- Schroeder B.E.
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- Schuldiner S.
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- Schwartz K.
- Seiden L.S.
- Seiden L.S.
- Seiden L.S.
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- Self D
- Self D.
- Self D.W.
- Self D.W.
- Self D.W.
- Sellings L.H.
- Series H.G.
- Series H.G.
- Sershen H.
- Sesack S.R.
- Setola V.
- Shank R.P.
- Shankaran M.
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- Trujillo K.
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- Unterwald E.
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- Unterwald E.M
- Unterwald E.M.
- Uramura K.
- Vailati S.
- Valjent E.
- Valjent E.
- Valjent E.
- Van de Kar L.D.
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- Villegier A.S.
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- Volkow N.
- Volkow N.
- Volkow N.
- Volkow N.
- Volkow N.D.
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- Volkow N.D.
- Volkow N.D.
- Volkow N.D.
- Volkow N.D.
- Volkow N.D.
- Volkow N.D.
- Volkow N.D.
- Vollenweider F.X.
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- Volz T.J.
- Wachtel H
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- Wagner G.C.
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- Walters C.L.
- Walters C.L.
- Wang F.
- Wang G.J.
- Wang G.J.
- Wang X.
- Wang X.
- Weddington W.W.
- Weintraub J.M.
- Weiss F.
- Wesson D.R
- West G.B.
- Westfall T.C.
- Wetli C.V.
- Wetli C.V.
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- White F.
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- Wilson J.
- Wilson J.M.
- Wilson J.M.
- Wilson L.D.
- Wilson M.
- Winhusen T.M.
- Wise R.A
- Witkin J
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- Witkin J.M.
- Wolf M.
- Wolf M.E.
- Wollemann M.
- Wong A.H.C.
- Wong G.
- Wonnacott S
- Wonnacott S.
- Wood M.D.
- Woodward J.J.
- Wooltorton J.R.
- Woolverton W.
- Woolverton W.L.
- Woolverton W.L.
- Worsley J.N.
- Worsley J.N.
- Wrona M.Z.
- Wu D.
- Wu J.
- Wu X.
- Xi Z.X.
- Xi Z.X.
- Xu Z.
- Yacoubian G.S. Jr.
- Yamamoto B.K.
- Yamamoto B.K.
- Yamashita H.
- Yan Q.S.
- Yan Z.
- Yeghiayan S.K.
- Yim H.J.
- Yokel R.A.
- Yoshimoto K.
- Yui K.
- Yui K.
- Yui K.
- Zachariou V.
- Zaczek R.
- Zaczek R.
- Zaczek R.
- Zeidonis D.
- Zeigler S.
- Zetterstrom T.
- Zhang D.
- Zhang H.
- Zhang X.
- Zhang X.Y.
- Zigmond M.J.
- Zimanyi I.
- Zito K.A.
- Zito K.A.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
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