General characteristics of the population.

<p>Values are mean ± standard deviation. For qualitative variables, data are expressed as (n, %)</p><p>* <i>p-value < 0</i>.<i>0001</i></p><p>General characteristics of the population.</p

Characteristics of selected Polymorphisms.

<p>HGN, The HUGO Gene Nomenclature.</p><p>^¥:Tag-SNP by Hapmap in Caucasian patients. Ensemble ID: Ensemble human release 53. SNP name: dbSNP129 (NCBI´s build 36, version 3)</p><p>Characteristics of selected Polymorphisms.</p

Association between obesity and BMI and SNPs of EDNRB genes adjusted by age and sex in: A-Valcar Study / B-Hortega Study / C-Both.

<p>HWE, Hardy—Weinberg equilibrium; MAF, minor allele frequency; SNP, single-nucleotide polymorphism; OR, odds ratio. Values are mean ± standard error. Bold indicates significance.</p><p>*dbSNP 129.</p><p>Association between obesity and BMI and SNPs of EDNRB genes adjusted by age and sex in: A-Valcar Study / B-Hortega Study / C-Both.</p

Linkage Disequilibrium (LD) plot of studied EDNRB SNPs. a) D´ b) R².

<p>Linkage Disequilibrium (LD) plot of studied EDNRB SNPs. a) D´ b) R².</p

Haplotype association analysis of rs5351 and rs3759475 of EDNRB gene with BMI and obesity risk adjusted by age and sex.

<p>Single nucleotide polymorphisms used in the haplotype construction: rs5351, rs3759475.</p><p>Haplotype association analysis of rs5351 and rs3759475 of EDNRB gene with BMI and obesity risk adjusted by age and sex.</p

Relation with Arsenic serum levels.

<p>Association between obesity and BMI and SNPs of EDNRB genes adjusted by age and sex. OR, odds ratio. Values are mean ± standard error. Bold indicates significance.</p><p>Relation with Arsenic serum levels.</p

Haplotype association analysis of rs5351 and rs3759475 of EDNRB gene with BMI and obesity risk adjusted by age and sex in relation with Arsenic serum levels.

<p>Single nucleotide polymorphisms used in the haplotype construction: rs5351, rs3759475.</p><p>Haplotype association analysis of rs5351 and rs3759475 of EDNRB gene with BMI and obesity risk adjusted by age and sex in relation with Arsenic serum levels.</p