These degrees go to eleven: fuzzy logics and gradable predicates

In the literature on vagueness one finds two very different kinds of degree theory. The dominant kind of account of gradable adjectives in formal semantics and linguistics is built on an underlying framework involving bivalence and classical logic: its degrees are not degrees of truth. On the other hand, fuzzy logic based theories of vagueness—largely absent from the formal semantics literature but playing a significant role in both the philosophical literature on vagueness and in the contemporary logic literature—are logically nonclassical and give a central role to the idea of degrees of truth. Each kind of degree theory has a strength: the classical kind allows for rich and subtle analyses of the comparative form of gradable adjectives and of various types of gradable precise adjectives, while the fuzzy kind yields a compelling solution to the sorites paradox. This paper argues that the fuzzy kind of theory can match the benefits of the classical kind and hence that the burden is on the latter to match the advantages of the former. In particular, we develop a new version of the fuzzy logic approach that—unlike existing fuzzy theories—yields a compelling analysis of the comparative as well as an adequate account of gradable precise predicates, while still retaining the advantage of genuinely solving the sorites paradox

Does the Efficacy of High Intensity Ventilation in Stable COPD Depend on the Ventilator Model? A Bench-to-Bedside Study

The European Task Force for chronic non-invasive ventilation in stable COPD recommends the use of high pressure-support (PS) level to maximize the decrease in PaCO2. It is possible that the ventilator model can influence the need for higher or lower pressure levels. To determine the differences between ventilators in a bench model with an increased inspiratory demand; and to compare the degree of muscular unloading measured by parasternal electromyogram (EMGpara) provided by the different ventilators in real patients with stable COPD. Bench: four levels of increasing progressive effort were programmed. The response of nine ventilators to four levels of PS and EPAP of 5 cm H2O was studied. The pressure-time product was determined at 300 and 500 msec (PTP 300/500). The ventilators were divided into two groups, based on the result of the bench test. Severe COPD patients with non-invasive ventilation (NIV) were studied, randomly comparing the performance of one ventilator from each group. Muscle unloading was measured by the decrease in EMGpara from its baseline value. There were significant differences in PTP 300 and PTP 500 in the bench study. Based on these results, home ventilators were classified into two groups; group 1 included four models with higher PTP 300. Ten COPD patients were recruited for the clinical study. Group 1 ventilators showed greater muscle unloading at the same PS than group 2. The scale of pressure support in NIV for high intensity ventilation may be influenced by the ventilator model. NCT0337317