449 research outputs found

    WT1 β’ing catenin into shape : a new interaction driving epigenetic plasticity in AML?

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    Photograph of Statue of Abraham Lincoln, Lincoln Square, Manchester

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    The black and white photograph depicts an image of a standing sculpture of Abraham Lincoln, which is located at Lincoln Square in Manchester, England. The sculpture was intended for display outside the Houses of Parliament, but Lincoln\u27s likeness was deemed controversial. Instead, the sculpture was installed in Manchester and a more statesmanlike sculpture was created for Parliament.https://scholarsjunction.msstate.edu/fvw-artifacts/2243/thumbnail.jp

    Photograph of Statue of Abraham Lincoln, Lincoln Square, Manchester

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    The black and white photograph depicts an image of a standing sculpture of Abraham Lincoln, which is located at Lincoln Square in Manchester, England. The sculpture was intended for display outside the Houses of Parliament, but Lincoln\u27s likeness was deemed controversial. Instead, the sculpture was installed in Manchester and a more statesmanlike sculpture was created for Parliament.https://scholarsjunction.msstate.edu/fvw-photographs/1617/thumbnail.jp

    Characterization of Genotype by Planting Date Effects on Runner-Type Peanut Seed Germination and Vigor Response to Temperature

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    Experiments evaluated the genotype by environment effects on seed germination and vigor of the peanut runner-type cultivars ‘Georgia Green’, ‘AT3085R0’, ‘AT271516’, ‘Georgia 03L’, and ‘FR458’ grown under similar production practices, for three planting dates: April, May, and June in Georgia and Alabama. Objectives were to determine if time of planting and harvest dates would subsequently affect germination and vigor when tested using a thermal gradient devise (temperature range14 to 35 °C). Runner-type peanut seed grown in Dawson Georgia in 2008 had the strongest seed vigor with Germ80 of 22 to 40 growing degree days (GDD), and maximum incidence of germination rate 84.8-95.7% when planted April, May, and June 2008 across 15 seed lots. In contrast, seed harvested from plantings of May 2009 at Dawson Georgia exhibited Germ80 of 24 to 40 GDD with maximum incidence of germination rate 79.8-93.6%, but seed from April 2009 plantings had poor vigor of 56.8-72.8% and no amount of GDD could achieve Germ80, with similar results for June 2009 plantings for this location. For Headland April, May, and June 2009 plantings of the same cultivars, all seed had poor vigor, ≤75.6% maximum incidence for germination rate, and none obtained a measurable Germ80

    Markers for human haematopoietic stem cells : The disconnect between an identification marker and its function

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    The haematopoietic system is a classical stem cell hierarchy that maintains all the blood cells in the body. Haematopoietic stem cells (HSCs) are rare, highly potent cells that reside at the apex of this hierarchy and are historically some of the most well studied stem cells in humans and laboratory models, with haematopoiesis being the original system to define functional cell types by cell surface markers. Whilst it is possible to isolate HSCs to near purity, we know very little about the functional activity of markers to purify HSCs. This review will focus on the historical efforts to purify HSCs in humans based on cell surface markers, their putative functions and recent advances in finding functional markers on HSCs

    Assessment of the Psychometric Properties of the Family Management Measure

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    Objective This paper reports development of the Family Management Measure (FaMM) of parental perceptions of family management of chronic conditions. Method By telephone interview, 579 parents of children age 3 to 19 with a chronic condition (349 partnered mothers, 165 partners, 65 single mothers) completed the FaMM and measures of child functional status and behavioral problems and family functioning. Analyses addressed reliability, factor structure, and construct validity. Results Exploratory factor analysis yielded six scales: Child's Daily Life, Condition Management Ability, Condition Management Effort, Family Life Difficulty, Parental Mutuality, and View of Condition Impact. Internal consistency reliability ranged from .72 to .91, and test-retest reliability from .71 to .94. Construct validity was supported by significant correlations in hypothesized directions between FaMM scales and established measures. Conclusion Results support FaMM's; reliability and validity, indicating it performs in a theoretically meaningful way and taps distinct aspects of family response to childhood chronic conditions
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