Galactic Bulge accreting binaries spectroscopy

Item does not contain fulltextWe present the identification of optical counterparts to 23 GBS X-ray sources. All sources are classified as accreting binaries according to the emission-line characteristics inferred from medium-resolution spectroscopy. To distinguish accreting binaries from chromospherically active objects, we develop criteria based on Hα and Hei λλ5786, 6678 emission-line properties available in the literature. The spectroscopic properties and photometric variability of each object is discussed and a classification is given where possible. At least 12 of the 23 systems show an accretion-dominated optical spectrum and another 6 show stellar absorption features in addition to emission lines indicating that they are probably accreting binaries in quiescence or in a low accretion rate state. Two sources are confirmed to be eclipsing: CX207 and CX794. CX207 is likely a magnetic cataclysmic variable (CV), while CX794 is a nova-like CV in the period gap. Finally, the large broadening (2100 km/s FWHM) of the Hα emission lines in CX446 and CX1004 suggests that they are also high-inclination or even eclipsing systems. Whether the compact object is a white dwarf in an eclipsing CV, a neutron star or a black hole in a high-inclination low-mass X-ray binary remains to be established

X-ray survey of the Galactic Bulge (CXOGBS)

We provide the Chandra source list for the last ∼quarter of the area covered by the Galactic Bulge Survey (GBS). The GBS targets two strips of 6°x1° (12 square degrees in total), one above (1° < b < 2°) and one below (-2° < b < -1°) the Galactic plane in the direction of the Galactic center at X-ray, optical, and near-infrared wavelengths. For the X-ray part of the survey we use 2 ks per Chandra pointing. We find 424 X-ray sources in the 63 Chandra observations on which we report here. These sources are in addition to the 1216 X-ray sources discovered in the first part of the GBS survey described previously. We discuss the characteristics and the X-ray variability of the brightest of the sources as well as the radio properties from existing radio surveys. We point out an interesting asymmetry in the number of X-ray sources as a function of their Galactic l and b coordinates which is probably caused by differences in average extinction toward the different parts of the GBS survey area

X-ray survey of the Galactic Bulge (CXOGBS)

Item does not contain fulltextWe provide the Chandra source list for the last ∼quarter of the area covered by the Galactic Bulge Survey (GBS). The GBS targets two strips of 6°x1° (12 square degrees in total), one above (1° < b < 2°) and one below (-2° < b < -1°) the Galactic plane in the direction of the Galactic center at X-ray, optical, and near-infrared wavelengths. For the X-ray part of the survey we use 2 ks per Chandra pointing. We find 424 X-ray sources in the 63 Chandra observations on which we report here. These sources are in addition to the 1216 X-ray sources discovered in the first part of the GBS survey described previously. We discuss the characteristics and the X-ray variability of the brightest of the sources as well as the radio properties from existing radio surveys. We point out an interesting asymmetry in the number of X-ray sources as a function of their Galactic l and b coordinates which is probably caused by differences in average extinction toward the different parts of the GBS survey area

Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation

The sirtuins are a protein family named after the first identified member, S. cerevisiae Sir2p. Sirtuins are protein deacetylases whose activity is dependent on NAD(+) as a cosubstrate. They are structurally defined by two central domains that together form a highly conserved catalytic center, which catalyzes the transfer of an acetyl moiety from acetyllysine to NAD(+), yielding nicotinamide, the unique metabolite O-acetyl-ADP-ribose and deacetylated lysine. One or more sirtuins are present in virtually all species from bacteria to mammals. Here we describe a phylogenetic analysis of sirtuins. Based on their phylogenetic relationship, sirtuins can be grouped into over a dozen classes and subclasses. Humans, like most vertebrates, have seven sirtuins: SIRT1-SIRT7. These function in diverse cellular pathways, regulating transcriptional repression, aging, metabolism, DNA damage responses and apoptosis. We show that these seven sirtuins arose early during animal evolution. Conserved residues cluster around the catalytic center of known sirtuin family members