Measurements of latency (a and b) and error rate (c and d) in the Barnes Maze for California mice males and females.

<p>In males, developmental exposure to BPA or EE did not affect latency or error rate in the Barnes Maze compared to CTL males. Likewise, no effects were observed in BPA- or EE-exposed females compared to CTL females.</p

Measurements of exploratory and anxiety-like behaviors in EPM.

<p>a) Time spent in the open arms of the EPM. No difference was evident in time spent in the open arms between BPA- and EE-exposed males compared to CTL California mice males. In contrast, CTL female California mice spent more time in the open arms than BPA-exposed females and CTL males. ^a,bDifferences between maternal diets within sex (P<0.05), and ^*differences between sexes within maternal diet (P = 0.05). b) Proportion of time spent in open arms, c) Time spent immobile, d) Total number of entries in all arms, e) Distance travelled, and f) Velocity. None of these other measurements were affected by sex or maternal diet.</p

Barnes maze search strategy.

<p>The graph depicts the usage of random (yellow), serial (green), and direct (black) search strategies by CTL, EE-, and BPA-exposed males and females. During the seven d trial period, there were no consistent differences in search strategy based on maternal diet or sex.</p

Measurement of territorial marking in BPA-exposed California mice males compared to CTL males.

<p>There was no difference on d 0 between BPA-exposed and CTL males, who did not have any visual or other sensory contact. When BPA-exposed and CTL males were placed in the same cage with a barrier between them, BPA-exposed males exhibited a trend to engage in less territorial marking on the first d of exposure (P<0.07) and even more so seven ds later than CTL males (*, P<0.003).</p

Body weight measurements of California mice males and females exposed to BPA, EE, and CTL diet.

<p>Measurements of body weight from 30 to 90 ds of age indicated that in males developmental exposure to BPA or EE did not affect body weight gain. In contrast, females exposed to EE weighed less than CTL females, EE males, and BPA females (P<0.05).</p