Electronic bill presentment and payment--is it just a click away?

This article addresses the following questions about electronic presentment and payment (EBPP) in the business-to-consumer marketplace: Why aren't electronically presented bills always paid electronically? And, if EBPP does aid in the migration to fully electronic end-to-end payment, what are the barriers to its adoption.Payment systems ; Electronic funds transfers

Investigation of the Effect of Contextual Factors on BIN Production in AAE

Treatments of African American English (AAE) in the literature have focused primarily on morphosyntactic differences from mainstream American English. One these differences is found in the tense and aspect system. While both dialects have the present perfect use for “been”, AAE also has a stressed variant of “been”, termed BIN. This aspectual marker is featured in the literature, but the main focus has been on its prosodic qualities. It differs from present perfect been in that it has the semantics of a remote past marker (Rickford 1973, Rickford 1975, Green 1998). For a comprehensive understanding of AAE’s tense aspect system, both syntactic-semantic and discourse-pragmatic aspects of these markers need to be studied as well. We complete a production experiment with members of an AAE-speaking community in Southwest Louisiana followed by an acceptability judgement task. The purpose of the experiment is twofold. First, it allows us to examine BIN production in canonical BIN environments and non-BIN environments. Second, by paying close attention to the context these environments occur in, we can also examine the influence of discourse-pragmatic factors (LONG-TIME, TEMPORAL JUST, POLAR QUESTIONS) on BIN production in unambiguous environments, as well as in ambiguous environments. The factors LONG-TIME and TEMPORAL JUST are found to be significant predictors of BIN production Furthermore, there is a significant difference in ambiguity, such that the unambiguous contexts predicted BIN slightly less. Overall, the results of the experiment suggest that speakers are consistent in their BIN production for expected BIN environments, but more variable in the non-BIN environments for both unambiguous and ambiguous contexts. This raises the interesting question of why speakers are more variable in the non-BIN environments as well as questioning what the discourse-pragmatic factors are actually capturing. Together, however, it suggests that there are a variety of components that can influence BIN production. Future areas of work could further investigate in regards these components

Intermediate filament–membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength

By tethering intermediate filaments (IFs) to sites of intercellular adhesion, desmosomes facilitate formation of a supercellular scaffold that imparts mechanical strength to a tissue. However, the role IF–membrane attachments play in strengthening adhesion has not been directly examined. To address this question, we generated Tet-On A431 cells inducibly expressing a desmoplakin (DP) mutant lacking the rod and IF-binding domains (DPNTP). DPNTP localized to the plasma membrane and led to dissociation of IFs from the junctional plaque, without altering total or cell surface distribution of adherens junction or desmosomal proteins. However, a specific decrease in the detergent-insoluble pool of desmoglein suggested a reduced association with the IF cytoskeleton. DPNTP-expressing cell aggregates in suspension or substrate-released cell sheets readily dissociated when subjected to mechanical stress whereas controls remained largely intact. Dissociation occurred without lactate dehydrogenase release, suggesting that loss of tissue integrity was due to reduced adhesion rather than increased cytolysis. JD-1 cells from a patient with a DP COOH-terminal truncation were also more weakly adherent compared with normal keratinocytes. When used in combination with DPNTP, latrunculin A, which disassembles actin filaments and disrupts adherens junctions, led to dissociation up to an order of magnitude greater than either treatment alone. These data provide direct in vitro evidence that IF–membrane attachments regulate adhesive strength and suggest furthermore that actin- and IF-based junctions act synergistically to strengthen adhesion

Whole-genome sequencing for national surveillance of Shiga toxin–producing Escherichia coli O157

Background. National surveillance of gastrointestinal pathogens, such as Shiga toxin–producing Escherichia coli O157 (STEC O157), is key to rapidly identifying linked cases in the distributed food network to facilitate public health interventions. In this study, we used whole-genome sequencing (WGS) as a tool to inform national surveillance of STEC O157 in terms of identifying linked cases and clusters and guiding epidemiological investigation. Methods. We retrospectively analyzed 334 isolates randomly sampled from 1002 strains of STEC O157 received by the Gastrointestinal Bacteria Reference Unit at Public Health England, Colindale, in 2012. The genetic distance between each isolate, as estimated by WGS, was calculated and phylogenetic methods were used to place strains in an evolutionary context. Results. Estimates of linked clusters representing STEC O157 outbreaks in England and Wales increased by 2-fold when WGS was used instead of traditional typing techniques. The previously unidentified clusters were often widely geographically distributed and small in size. Phylogenetic analysis facilitated identification of temporally distinct cases sharing common exposures and delineating those that shared epidemiological and temporal links. Comparison with multi locus variable number tandem repeat analysis (MLVA) showed that although MLVA is as sensitive as WGS, WGS provides a more timely resolution to outbreak clustering. Conclusions. WGS has come of age as a molecular typing tool to inform national surveillance of STEC O157; it can be used in real time to provide the highest strain-level resolution for outbreak investigation. WGS allows linked cases to be identified with unprecedented specificity and sensitivity that will facilitate targeted and appropriate public health investigations

Engaging Low-Income Parents in Childhood Obesity Prevention from Start to Finish: A Case Study

Prevention of childhood obesity is a national priority. Parents influence young children’s healthy lifestyles, so it is paradoxical that obesity interventions focus primarily on children. Evidence and theory suggest that including parents in interventions offers promise for effective childhood obesity prevention. This case study engaged parents’ as co-researchers in the design, implementation and evaluation of an intervention for low-income families with a child enrolled in Head Start. Parent engagement mechanisms include: (1) targeted partnership development (2) operationalizing a Community Advisory Board (CAB) that was the key decision making body; (3) a majority of CAB members were parents who were positioned as experts, and (4) addressing structural barriers to parent participation. Lessons learned are provided for future research, and practice

The SAMI Galaxy Survey: Shocks and Outflows in a normal star-forming galaxy

We demonstrate the feasibility and potential of using large integral field spectroscopic surveys to investigate the prevalence of galactic-scale outflows in the local Universe. Using integral field data from SAMI and the Wide Field Spectrograph, we study the nature of an isolated disk galaxy, SDSS J090005.05+000446.7 (z = 0.05386). In the integral field datasets, the galaxy presents skewed line profiles changing with position in the galaxy. The skewed line profiles are caused by different kinematic components overlapping in the line-of-sight direction. We perform spectral decomposition to separate the line profiles in each spatial pixel as combinations of (1) a narrow kinematic component consistent with HII regions, (2) a broad kinematic component consistent with shock excitation, and (3) an intermediate component consistent with shock excitation and photoionisation mixing. The three kinematic components have distinctly different velocity fields, velocity dispersions, line ratios, and electron densities. We model the line ratios, velocity dispersions, and electron densities with our MAPPINGS IV shock and photoionisation models, and we reach remarkable agreement between the data and the models. The models demonstrate that the different emission line properties are caused by major galactic outflows that introduce shock excitation in addition to photoionisation by star-forming activities. Interstellar shocks embedded in the outflows shock-excite and compress the gas, causing the elevated line ratios, velocity dispersions, and electron densities observed in the broad kinematic component. We argue from energy considerations that, with the lack of a powerful active galactic nucleus, the outflows are likely to be driven by starburst activities. Our results set a benchmark of the type of analysis that can be achieved by the SAMI Galaxy Survey on large numbers of galaxies.Comment: 17 pages, 15 figures. Accepted to MNRAS. References update

Community-Informed Relationship Violence Intervention in a HighStress, Low-Income Urban Context

To evaluate the effectiveness of the House of Ruth Maryland’s Gateway Project, a community-informed and oppression-sensitive relationship violence intervention program (RVIP; commonly labeled “batterer intervention”), designed for a predominantly low-income, racial minority population residing in a high-stress urban context. Method: Propensity score matching with data on 744 male program participants (89% Black; 59% unemployed; 76% on probation) was used to compare recidivism rates for those who did, and did not, complete the intervention program. The propensity score matching created comparison groups (n = 216 per group) with very similar distributions on 28 balancing factors. Results: During the year after program enrollment, program completers had significantly lower frequency of re-arrest for all criminal offenses, d = 0.16, p = .018 and marginally lower frequency of violent offenses, d = 0.12, p = .075 than matched non-completers. No treatment effect was identified for partner-abuse-related legal involvements, d = 0.06, p = .365. Secondary analyses controlling for propensity score in the full sample yielded similar results, and analyses of session attendance as a continuous variable found additional evidence of a significant program effect on violent offenses in the matched sample. Conclusions: In contrast to a carefully matched sample of program non-completers, men who completed this 28-session intervention, which adapts the traditional RVIP focus on power and control to address the life context of participants who experience systemic oppression, discrimination, economic distress, and community violence, had lower overall involvement with the criminal justice system

Molecular evolution of dengue type 2 virus in Thailand

Dengue is a mosquito-borne viral infection that in recent years has become a major international public health concern. Dengue hemorrhagic fever (DHF), first recognized in Southeast Asia in the 1950s, is today a leading cause of childhood death in many countries. The pathogenesis of this illness is poorly understood, mainly because there are no laboratory or animal models of disease. We have studied the genetic relationships of dengue viruses of serotype 2, one of four antigenically distinct dengue virus groups, to determine if viruses obtained from cases of less severe dengue fever (DF) have distinct evolutionary origins from those obtained from DHF cases. A very large number (73) of virus samples from patients with DF or DHF in two locations in Thailand (Bangkok and Kamphaeng Phet) were compared by sequence analysis of 240 nucleotides from the envelope/nonstructural protein 1 (E/NS1) gene junction of the viral genome. Phylogenetic trees generated with these data have been shown to reflect long-term evolutionary relationships among strains. The results suggest that 1) many different virus variants may circulate simultaneously in Thailand, thus reflecting the quasispecies nature of these RNA viruses, in spite of population immunity; 2) viruses belonging to two previously distinct genotypic groups have been isolated from both DF and DHF cases, supporting the view that they arose from a common progenitor and share the potential to cause severe disease; and 3) viruses associated with the potential to cause DHF segregate into what is now one, large genotypic group and they have evolved independently in Southeast Asia for some time

Scale-dependent spatial patterns in benthic communities around a tropical island seascape

Understanding and predicting patterns of spatial organization across ecological communities is central to the field of landscape ecology, and a similar line of inquiry has begun to evolve sub-tidally among seascape ecologists. Much of our current understanding of the processes driving marine community patterns, particularly in the tropics, has come from small-scale, spatially-discrete data that are often not representative of the broader seascape. Here we expand the spatial extent of seascape ecology studies and combine spatially-expansive in situ digital imagery, oceanographic measurements, spatial statistics, and predictive modeling to test whether predictable patterns emerge between coral reef benthic competitors across scales in response to intra-island gradients in physical drivers. We do this around the entire circumference of a remote, uninhabited island in the central Pacific (Jarvis Island) that lacks the confounding effects of direct human impacts. We show, for the first time, that competing benthic groups demonstrate predictable scaling patterns of organization, with positive autocorrelation in the cover of each group at scales \u3c ~1 km. Moreover, we show how gradients in subsurface temperature and surface wave power drive spatially-abrupt transition points in group dominance, explaining 48–84% of the overall variation in benthic cover around the island. Along the western coast, we documented ten times more sub-surface cooling-hours than any other part of the coastline, with events typically resulting in a drop of 1–4°C over a period of \u3c 5 h. These high frequency temperature fluctuations are indicative of upwelling induced by internal waves and here result in localized nitrogen enrichment (NO 2 + NO 3 ) that promotes hard coral dominance around 44% of the island\u27s perimeter. Our findings show that, in the absence of confounding direct human impacts, the spatial organization of coral reef benthic competitors are predictable and somewhat bounded across the seascape by concurrent gradients in physical drivers