7 research outputs found

    Estimation of the burden of varicella in Europe before the introduction of universal childhood immunization

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    Seroprevalence of VZV in Norway.

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    <p>Posterior mean of the age-specific VZV seroprevalence in Norway (with 95% CI), determined using the mixture model.</p

    Distribution of antibodies to VZV by age in Norway.

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    <p>Histogram of the log-transformed antibody optical densities (log<sub>10</sub>(OD+1)) against VZV by broad age group (preschool: 1–5 years; school: 6–18 years; adults: 19 years and more), with over imposed the corresponding density function estimated by the mixture model, for each component (dotted line), and for all the data (solid line). The vertical dashed lines represent the manufacturer’s fixed cut-offs and the data included between the two lines are usually classified as inconclusive under the conventional cut-off approach.</p

    Proportions VZV-positive individuals in Norway.

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    <p>Age-specific proportions seropositive determined using the fixed cut-off (grey bars) and the mixture model (black dots). For the latter ones, we also reported the 95% pointwise credible intervals (grey area).</p
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