16,980 research outputs found

    4-H Youth Leaders: Acquisition of Leadership Skills Based on Perceived Influence

    Get PDF
    This study focuses on youth perceptions of influence on others and leadership skills they may seek to acquire, particularly within the Maine 4-H program. Understanding the relationship between the youth perception of leadership influence and the skills they seek to acquire will enable 4-H club leaders and adult mentors to better facilitate acquisition of leadership skills. This study gains understanding from the perspective of current teen leaders in the Maine 4-H program through the use of personal interviews with active teen leaders. Findings indicate that Maine 4-H Teen Leaders do not necessarily recognize the influence they have with their peers and therefore, do not tend to seek out new leadership skills based on their perceived influence. Though some youths are interested in developing their leadership skills, being able to recognize their positive influence on others appears to be gap in overall leadership understanding

    Assessing the Sensitivity of Different Life Stages for Sexual Disruption in Roach (Rutilus rutilus) Exposed to Effluents from Wastewater Treatment Works

    Get PDF
    Surveys of U.K. rivers have shown a high incidence of sexual disruption in populations of wild roach (Rutilus rutilus) living downstream from wastewater treatment works (WwTW), and the degree of intersex (gonads containing both male and female structural characteristics) has been correlated with the concentration of effluent in those rivers. In this study, we investigated feminized responses to two estrogenic WwTWs in roach exposed for periods during life stages of germ cell division (early life and the postspawning period). Roach were exposed as embryos from fertilization up to 300 days posthatch (dph; to include the period of gonadal sex differentiation) or as postspawning adult males, and including fish that had received previous estrogen exposure, for either 60 or 120 days when the annual event of germ cell proliferation occurs. Both effluents induced vitellogenin synthesis in both life stages studied, and the magnitude of the vitellogenic responses paralleled the effluent content of steroid estrogens. Feminization of the reproductive ducts occurred in male fish in a concentration-dependent manner when the exposure occurred during early life, but we found no effects on the reproductive ducts in adult males. Depuration studies (maintenance of fish in clean water after exposure to WwTW effluent) confirmed that the feminization of the reproductive duct was permanent. We found no evidence of ovotestis development in fish that had no previous estrogen exposure for any of the treatments. In wild adult roach that had previously received exposure to estrogen and were intersex, the degree of intersex increased during the study period, but this was not related to the immediate effluent exposure, suggesting a previously determined programming of ovotestis formation

    Data Integration and Storage: Managing and Using Home and Community-Based Services Data for Quality Improvement

    Get PDF
    This paper reports on data integration from a program manager’s perspective. The paper is not meant to be an exhaustive research document, nor does it single out any one correct approach. The paper is meant to facilitate communication between program units and analytic staff and serve as one reference for states as they continue to improve upon data collection techniques and use this information for ongoing quality management and improvement

    Tumor detection and elimination by a targeted gallium corrole

    Get PDF
    Sulfonated gallium(III) corroles are intensely fluorescent macrocyclic compounds that spontaneously assemble with carrier proteins to undergo cell entry. We report in vivo imaging and therapeutic efficacy of a tumor-targeted corrole noncovalently assembled with a heregulin-modified protein directed at the human epidermal growth factor receptor (HER). Systemic delivery of this protein-corrole complex results in tumor accumulation, which can be visualized in vivo owing to intensely red corrole fluorescence. Targeted delivery in vivo leads to tumor cell death while normal tissue is spared. These findings contrast with the effects of doxorubicin, which can elicit cardiac damage during therapy and required direct intratumoral injection to yield similar levels of tumor shrinkage compared with the systemically delivered corrole. The targeted complex ablated tumors at >5 times a lower dose than untargeted systemic doxorubicin, and the corrole did not damage heart tissue. Complexes remained intact in serum and the carrier protein elicited no detectable immunogenicity. The sulfonated gallium(III) corrole functions both for tumor detection and intervention with safety and targeting advantages over standard chemotherapeutic agents

    "The impact of mediation on resolution of disagreements around special educational needs: Effectiveness and cost effectiveness"

    Get PDF
    Under England’s Children and Families Act 2014, local authorities (LAs) have a statutory responsibility to provide an independent mediation service for cases of disagreement between parents or young people and the LAs where parents or the young person are considering an appeal to the First-tier Tribunal Special Educational Needs (SEN) and DisabilityWe examined the effectiveness and cost effectiveness of mediation in resolving such disagreements without recourse to an appeal to the Tribunal. Our data comprised three national surveys, two supplementary surveys and individual interviews with LA staff and parents to explore implementation of the new mediation system and the impact on appeals and costs over 2014–16 from 109 English LAs who provided data. Our findings indicate that families who took up mediation were significantly less likely to appeal to the Tribunal, absolute risk reduction 13.58% (95% CI: 10.20%, 16.97%). The cost saving across all cases, of different complexity, was £636,462 overall, approximately £500 per case. Overall, mediation was found to be a promising method of disagreement resolution, reducing appeals and producing savings in both financial and human well-being costs. To the best of our knowledge, this is the first study of both the effectiveness and cost effectiveness of mediation as a means of resolution of disputes about meeting children's SEN

    Open Transactions on Shared Memory

    Full text link
    Transactional memory has arisen as a good way for solving many of the issues of lock-based programming. However, most implementations admit isolated transactions only, which are not adequate when we have to coordinate communicating processes. To this end, in this paper we present OCTM, an Haskell-like language with open transactions over shared transactional memory: processes can join transactions at runtime just by accessing to shared variables. Thus a transaction can co-operate with the environment through shared variables, but if it is rolled-back, also all its effects on the environment are retracted. For proving the expressive power of TCCS we give an implementation of TCCS, a CCS-like calculus with open transactions

    A study of snake-like locomotion through the analysis of a flexible robot model

    Get PDF
    We examine the problem of snake-like locomotion by studying a system consisting of a planar inextensible elastic rod with adjustable spontaneous curvature, which provides an internal actuation mechanism that mimics muscular action in a snake. Using a Cosserat model, we derive the equations of motion in two special cases: one in which the rod can only move along a prescribed curve, and one in which the rod is constrained to slide longitudinally without slipping laterally, but the path is not fixed a priori (free-path case). The second setting is inspired by undulatory locomotion of snakes on flat surfaces. The presence of constraints leads in both cases to non-standard boundary conditions that allow us to close and solve the equations of motion. The kinematics and dynamics of the system can be recovered from a one-dimensional equation, without any restrictive assumption on the followed trajectory or the actuation.We derive explicit formulae highlighting the role of spontaneous curvature in providing the driving force (and the steering, in the free-path case) needed for locomotion. We also provide analytical solutions for a special class of serpentine motions, which enable us to discuss the connection between observed trajectories, internal actuation and forces exchanged with the environment

    Yukawa Textures From Heterotic Stability Walls

    Full text link
    A holomorphic vector bundle on a Calabi-Yau threefold, X, with h^{1,1}(X)>1 can have regions of its Kahler cone where it is slope-stable, that is, where the four-dimensional theory is N=1 supersymmetric, bounded by "walls of stability". On these walls the bundle becomes poly-stable, decomposing into a direct sum, and the low energy gauge group is enhanced by at least one anomalous U(1) gauge factor. In this paper, we show that these additional symmetries can strongly constrain the superpotential in the stable region, leading to non-trivial textures of Yukawa interactions and restrictions on allowed masses for vector-like pairs of matter multiplets. The Yukawa textures exhibit a hierarchy; large couplings arise on the stability wall and some suppressed interactions "grow back" off the wall, where the extended U(1) symmetries are spontaneously broken. A number of explicit examples are presented involving both one and two stability walls, with different decompositions of the bundle structure group. A three family standard-like model with no vector-like pairs is given as an example of a class of SU(4) bundles that has a naturally heavy third quark/lepton family. Finally, we present the complete set of Yukawa textures that can arise for any holomorphic bundle with one stability wall where the structure group breaks into two factors.Comment: 53 pages, 4 figures and 13 table
    corecore