301 research outputs found
Modified POF Sensor for Gaseous Hydrogen Fluoride Monitoring in the Presence of Ionizing Radiations
This paper describes the development of a sensor designed to detect low concentrations of hydrogen fluoride (HF) in gas mixtures. The sensor employs a plastic optical fiber (POF) covered with a thin layer of glass- like material. HF attacks the glass and alters the fiber transmission capability so that the detection simply requires a LED and a photodiode. The coated POF is obtained by means of low-pressure plasma-enhanced chemical vapor deposition that allows the glass-like film to be deposited at low temperature without damaging the fiber core. The developed sensor will be installed in the recirculation gas system of the resistive plate chamber muon detector of the Compact Muon Solenoid experiment at the Large Hadron Collider accelerator of the European Organization for Nuclear Research (CERN
Conservazione e sicurezza strutturale di colonne in ghisa prodotte e montate in opera nel XIX secolo
riassunto esteso e presentazione orale al convegno Workshop IGF - Problematiche di Frattura nei Materiali per l'Ingegneria, Forni di Sopra (UD), 7/1/2010 - 9/1/201
Properties of potential eco-friendly gas replacements for particle detectors in high-energy physics
Gas detectors for elementary particles require F-based gases for optimal performance.
Recent regulations demand the use of environmentally unfriendly F-based gases to be limited or
banned. This work studies properties of potential eco-friendly gas replacements by computing the
physical and chemical parameters relevant for use as detector media, and suggests candidates to be
considered for experimental investigation
Properties of potential eco-friendly gas replacements for particle detectors in high-energy physics
Modern gas detectors for detection of particles require F-based gases for
optimal performance. Recent regulations demand the use of environmentally
unfriendly F-based gases to be limited or banned. This review studies
properties of potential eco-friendly gas candidate replacements.Comment: 38 pages, 9 figures, 8 tables. To be submitted to Journal of
Instrumentatio
Candidate eco-friendly gas mixtures for MPGDs
Modern gas detectors for detection of particles require F-based gases for optimal performance.Recent regulations demand the use of environmentally unfriendly F-based gases t o be limited or banned. This review studies properties of potential eco-friendly gas candidate replacements
ToF-SIMS and -Raman measurements on laser cleaned bronze archaeological artefacts
n this study, ToF-SIMS and -Raman analyses have been employed to assess the feasibility of laser treatments as a selective, non invasive cleaning methodology for archaeological metallic artefacts. A Q-switched Yb:YAG fibre laser, operating at 1064 nm, has been used for the cleaning treatments, carried out in air and 18O rich atmosphere on an ancient bronze coin. The preliminary results show that laser cleaning treatment selectively removes the dangerous oxyhydroxy chlorides corrosion products without affecting the cuprite protective patina grown directly in contact with the metallic surface
Decipher the glioblastoma microenvironment: The first milestone for new groundbreaking therapeutic strategies
Glioblastoma (GBM) is the most common primary malignant brain tumour in adults. Despite the combination of novel therapeutical approaches, it remains a deadly malignancy with an abysmal prognosis. GBM is a polymorphic tumour from both molecular and histological points of view. It consists of different malignant cells and various stromal cells, contributing to tumour initiation, progression, and treatment response. GBMâs microenvironment is multifaceted and is made up of soluble factors, extracellular matrix components, tissue-resident cell types (e.g., neurons, astrocytes, endothelial cells, pericytes, and fibroblasts) together with resident (e.g., microglia) or recruited (e.g., bone marrow-derived macrophages) immune cells. These latter constitute the so-called immune microenvironment, accounting for a substantial GBMâs tumour volume. Despite the abundance of immune cells, an intense state of tumour immunosuppression is promoted and developed; this represents the significant challenge for cancer cellsâ immune-mediated destruction. Though literature data suggest that distinct GBMâs subtypes harbour differences in their microenvironment, its role in treatment response remains obscure. However, an in-depth investigation of GBMâs microenvironment may lead to novel therapeutic opportunities to improve patientsâ outcomes. This review will elucidate the GBMâs microenvironment composition, highlighting the current state of the art in immunotherapy approaches. We will focus on novel strategies of active and passive immunotherapies, including vaccination, gene therapy, checkpoint blockade, and adoptive T-cell therapies
Characterization of the water diffusion in GEM foil material
Systematic studies on the GEM foil material are performed to measure the moisture diffusion rate and saturation level.These studies are important because the presence of this compound inside the detectorâs foil can possibly change its mechanical and electrical properties,and in such a way,the detector performance can be affected.To understand this phenomenon,a model is developed with COMSOL Multiphysicsv.4.3 which described the adsorption and diffusion within the geometry of GEM foil,the concentration profiles and the time required to saturate the foil.The COMSOL model is verified by experimental observations on a GEM foil sample.This note will describe the model and its experimental verification results
Conservazione e sicurezza strutturale di colonne in ghisa prodotte e montate in opera nel XIX secolo
riassunto esteso e presentazione orale al convegno Workshop IGF - Problematiche di Frattura nei Materiali per lâIngegneria, Forni di Sopra (UD), 7/1/2010 - 9/1/201
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