Cosmologies with a time dependent vacuum

The idea that the cosmological term, Lambda, should be a time dependent quantity in cosmology is a most natural one. It is difficult to conceive an expanding universe with a strictly constant vacuum energy density, namely one that has remained immutable since the origin of time. A smoothly evolving vacuum energy density that inherits its time-dependence from cosmological functions, such as the Hubble rate or the scale factor, is not only a qualitatively more plausible and intuitive idea, but is also suggested by fundamental physics, in particular by quantum field theory (QFT) in curved space-time. To implement this notion, is not strictly necessary to resort to ad hoc scalar fields, as usually done in the literature (e.g. in quintessence formulations and the like). A "running" Lambda term can be expected on very similar grounds as one expects (and observes) the running of couplings and masses with a physical energy scale in QFT. Furthermore, the experimental evidence that the equation of state of the dark energy could be evolving with time/redshift (including the possibility that it might currently behave phantom-like) suggests that a time-variable Lambda term (possibly accompanied by a variable Newton's gravitational coupling G=G(t)) could account in a natural way for all these features. Remarkably enough, a class of these models (the "new cosmon") could even be the clue for solving the old cosmological constant problem, including the coincidence problem.Comment: LaTeX, 15 pages, 4 figure

Effective growth of matter density fluctuations in the running LCDM and LXCDM models

We investigate the matter density fluctuations \delta\rho/\rho for two dark energy (DE) models in the literature in which the cosmological term \Lambda is a running parameter. In the first model, the running LCDM model, matter and DE exchange energy, whereas in the second model, the LXCDM model, the total DE and matter components are conserved separately. The LXCDM model was proposed as an interesting solution to the cosmic coincidence problem. It includes an extra dynamical component, the "cosmon" X, which interacts with the running \Lambda, but not with matter. In our analysis we make use of the current value of the linear bias parameter, b^2(0)= P_{GG}/P_{MM}, where P_{MM} ~ (\delta\rho/\rho)^2 is the present matter power spectrum and P_{GG} is the galaxy fluctuation power spectrum. The former can be computed within a given model, and the latter is found from the observed LSS data (at small z) obtained by the 2dF galaxy redshift survey. It is found that b^2(0)=1 within a 10% accuracy for the standard LCDM model. Adopting this limit for any DE model and using a method based on the effective equation of state for the DE, we can set a limit on the growth of matter density perturbations for the running LCDM model, the solution of which is known. This provides a good test of the procedure, which we then apply to the LXCDM model in order to determine the physical region of parameter space, compatible with the LSS data. In this region, the LXCDM model is consistent with known observations and provides at the same time a viable solution to the cosmic coincidence problem.Comment: LaTeX, 38 pages, 8 figures. Version accepted in JCA

FRCM-to-masonry bonding behaviour in the case of curved surfaces: Experimental investigation

Fabric-reinforced cementitious matrix (FRCM) are composite materials more and more used for the reinforcement of masonry structures. The combination of high tensile strength fabrics (or meshes) with cementitious matrices, having good thixotropic capabilities and vapour permeability, makes such composites suitable for reinforcing a large number of masonry structures, including the one belonging to the historic heritage. FRCMs are bonded to the outer surfaces of structural masonry elements and, thanks to their adhesive capacity, bear much of the tensile stresses that unreinforced masonry cannot withstand. The effectiveness of such reinforcements, which is highly dependent on their ability to adhere to the masonry substrate, is generally investigated throughout specific experimental investigations (shear tests). Almost all the papers in the literature devoted to bond-slip analysis refer to the case of flat bonding surfaces, although these reinforcements are also widely used on curved structural elements such as arches and vaults. Therefore, this paper reports and examines the results of an extensive experimental program concerning the behavior of FRCM systems applied on curved masonry specimens. The results point out the influence of both curvature and reinforcement position (intrados or extrados) on the response of specimens in terms of bearing capacity, failure mode and post-peak response

Data-Driven Stability Assessment of Multilayer Long Short-Term Memory Networks

Recurrent Neural Networks (RNNs) are increasingly being used for model identification, forecasting and control. When identifying physical models with unknown mathematical knowledge of the system, Nonlinear AutoRegressive models with eXogenous inputs (NARX) or Nonlinear AutoRegressive Moving-Average models with eXogenous inputs (NARMAX) methods are typically used. In the context of data-driven control, machine learning algorithms are proven to have comparable performances to advanced control techniques, but lack the properties of the traditional stability theory. This paper illustrates a method to prove a posteriori the stability of a generic neural network, showing its application to the state-of-the-art RNN architecture. The presented method relies on identifying the poles associated with the network designed starting from the input/output data. Providing a framework to guarantee the stability of any neural network architecture combined with the generalisability properties and applicability to different fields can significantly broaden their use in dynamic systems modelling and control

Dilution versus pollution in watercourses affected by acid mine drainage: a graphic model for the Iberian Pyrite Belt (SW Spain)

The aim of this study was to chemically characterize the water quality impacts of the 88 acid mine drainage (AMD) generating mines in the Spanish sector of the Iberian Pyrite Belt (IPB). This was necessary because the Water Framework Directive of the European Union and the hydrological plans of the Tinto, Odiel, and Piedras river basins require that water quality be improved enough to allow at least some of the rivers in the IPB to sustain healthy fish populations by 2027. The results indicate a clear decrease in metals, arsenic, and sulfate concentrations and increased pH between the AMD-sources and the river channels.info:eu-repo/semantics/publishedVersio

Tyrosine kinase inhibitors for the therapy of anaplastic thyroid cancer

Anaplastic thyroid cancer (ATC) is often incurable so new therapeutic approaches are needed. Tyrosine kinases inhibitors (such as imanitib, sunitinib or sorafenib) are under evaluation for the treatment of ATC. Other vascular disrupting agents, such as combretastatin A4 phosphate, and antiangiogenic agents, such as aplidin, PTK787/ZK222584 and human VEGF monoclonal antibodies (bevacizumab, cetuximab), have been evaluated. Small-molecule adenosine triphosphate competitive inhibitors directed intracellularly at EGFRs tyrosine kinase, such as erlotinib or gefitinib, are also studied. Furthermore, new molecules have been shown to be active against ATC, such as CLM94 and CLM3. However, more research is needed to finally identify therapies able to control and to cure this disease