Geometric mean (95% CI) IL-8 responses of nasal AEC incubated with (A) increasing concentrations of TNF-α/IL-1β (n = 15), (B) increasing concentrations of HDM (n = 10) and (C) media, HDM (25 µg/ml) and IL-1β and TNF-α (both at 10 ng/ml) for 24 hours (n = 52).

<p>Repeated measures ANOVA and paired t-tests for statistical significance.</p

An Open-Label Investigation of the Pharmacokinetics and Tolerability of Oral Cysteamine in Adults with Cystic Fibrosis

<p>The full text of this article can be found here:</p><p></p><p><a href="https://link.springer.com/article/10.1007/s40261-016-0405-z">https://link.springer.com/article/10.1007/s40261-016-0405-z</a></p><br><p></p

Technique for harvesting nasal epithelial cells from newborn infants.

<p>Written informed consent, as outlined in the PLOS consent form, to publication of this photograph was given by the child’s legal guardian.</p

Antenatal and delivery data of sampled neonates (n = 149) recruited to the cohort study.

<p>Antenatal and delivery data of sampled neonates (n = 149) recruited to the cohort study.</p

Cytospin of nasal sample obtained by brushing (size marker = 200 µm).

<p>Cytospin of nasal sample obtained by brushing (size marker  =  200 µm).</p

Characteristics of cell growth by passage.

<p>Characteristics of cell growth by passage.</p

Mean z scores for femur length, abdominal circumference and biparietal diameter for fetuses exposed to maternal smoking relative to non-exposed fetuses.

<p>The vertical lines correspond to 95% confidence intervals.</p

Summary of results from the papers identified in the systematic review.

<p>Summary of results from the papers identified in the systematic review.</p

Summary of meta-analyses relating maternal smoking to absolute and standardised second and third trimester fetal measurements.

<p>Summary of meta-analyses relating maternal smoking to absolute and standardised second and third trimester fetal measurements.</p

Additional file 1: of FourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations

SPIRIT 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 121 kb