Graduate Recital: Grace Yun-Yau Pun, Piano; April 4, 1976

Hayden AuditoriumSunday AfternoonApril 4, 19762:00 p.m

Quantifying The Role Of Insurance In Tornado-Impacted Community Recovery: A Survey And Simulation-Based Approach

Insurance against disasters plays a critical role in community recovery by providing policyholders with reliable and timely payments for repairing or reconstructing damaged houses. By allowing homeowners to transfer risk, insurance enables homeowners to address house without experiencing significant financial burdens. Although historical events have highlighted the importance of insurance, its quantitative impact on community recovery, particularly in tornado-impacted communities, is understudied. This study focuses on advancing our understanding of whether sufficiently insured houses can have a positive impact on the recovery of tornado-impacted communities (i.e., the main research question). This paper proposes a two-stage simulation framework to quantitatively evaluate the effects of insurance on community recovery. In the first stage of the framework, we developed statistical models to estimate homeowners\u27 insurance decisions prior to a tornado event. In the second stage, we examined the effects of insurance on various aspects of community recovery. To develop empirical and statistical models regarding insurance decisions and their impacts on housing recovery, we collected data through online surveys targeting residents whose properties were damaged by the tornadoes that occurred in May 2019 in the United States. Finally, the proposed simulation framework was applied to the City of Dayton, Ohio following those May 2019 tornado events to address the main research question. The results of the simulation concluded that sufficiently insured houses can have a positive impact on community recovery and highlighted the need for effective policies and economic incentives to encourage individuals to purchase insurance

How Korean K-12 Educators Adapted to Online Teaching and Promoted Digital Equity During COVID-19: A Mixed-Method Study on Practices and Perceptions

The abrupt transitions to online teaching during COVID-19 have exacerbated educational discrepancies worldwide. South Korean schools faced similar challenges primarily due to the insufficient infrastructure and pedagogical guidelines for online teaching. This mixed-method case study investigated how Korean K-12 teachers and administrators converted to online teaching and addressed related digital equity issues during their first semester of online teaching in response to the pandemic. Interviews, as well as survey responses at the beginning and end of the semester, were analyzed through Activity Theory (AT) and Technological Pedagogical Content Knowledge (TPACK) frameworks. The study's key insights were that the digital equity issue is related to quality teaching issues beyond infrastructural problems and that teachers took various strategies to maximize the effectiveness of their blended teaching. We aim to shed light on supporting equitable online learning and sustaining positive changes in the post-COVID era

From There to Here: Evaluating the Transition of an International Advanced Pharmacy Practice Experience in London

Purdue University College of Pharmacy offers an international advanced pharmacy practice experience (APPE) in London, England, where student pharmacists have the opportunity to work with pharmacy specialists at St. Bartholomew’s Hospital. The COVID-19 pandemic has significantly impacted travel across the world and created the need to transition this experience from in-person to virtual. Virtual interaction with international preceptors and revised research and clinical activities can provide students with a valuable learning experience

A novel modified-indirect ELISA based on spherical body protein 4 for detecting antibody during acute and long-term infections with diverse Babesia bovis strains

Cattle sera positive by the RAP-1-based cELISA but negative by the SBP4-based MI-ELISA and IFA had negative results by Western blot analysis, suggesting possible false positive results in the cELISA. A. Molecular weight marker (48 to 180 Kd), B. K42-#21, C. W31-#Y-3, D. W31-#Y-11, E. W31-#0-3, F. W31-#Y-9, G. W31-#0-9, H. W31-#Y-10, I. W31-#Y-15, J. P21-#224, K. positive control serum with a band at 75kd representing B. bovis RAP-1 protein, J. negative control serum. Figure S2. Technical difference between the modified indirect ELISA and conventional indirect ELISA using rGST-SBP4 was illustrated in this figure. (DOCX 645 kb

A Pan-Dengue Virus Reverse Transcription-Insulated Isothermal PCR Assay Intended for Point-of-Need Diagnosis of Dengue Virus Infection by Use of the POCKIT Nucleic Acid Analyzer

Dengue virus (DENV) infection is considered a major public health problem in developing tropical countries where the virus is endemic and continues to cause major disease outbreaks every year. Here, we describe the development of a novel, inexpensive, and user-friendly diagnostic assay based on a reverse transcription-insulated isothermal PCR (RT-iiPCR) method for the detection of all four serotypes of DENV in clinical samples. The diagnostic performance of the newly established pan-DENV RT-iiPCR assay targeting a conserved 3′ untranslated region of the viral genome was evaluated. The limit of detection with a 95% confidence was estimated to be 10 copies of in vitro-transcribed (IVT) RNA. Sensitivity analysis using RNA prepared from 10-fold serial dilutions of tissue culture fluid containing DENVs suggested that the RT-iiPCR assay was comparable to the multiplex real-time quantitative RT-PCR (qRT-PCR) assay for DENV-1, -3, and -4 detection but 10-fold less sensitive for DENV-2 detection. Subsequently, plasma collected from patients suspected of dengue virus infection (n = 220) and individuals not suspected of dengue virus infection (n = 45) were tested by the RT-iiPCR and compared to original test results using a DENV NS1 antigen rapid test and the qRT-PCR. The diagnostic agreement of the pan-DENV RT-iiPCR, NS1 antigen rapid test, and qRT-PCR tests was 93.9%, 84.5%, and 97.4%, respectively, compared to the composite reference results. This new RT-iiPCR assay along with the portable POCKIT nucleic acid analyzer could provide a highly reliable, sensitive, and specific point-of-need diagnostic assay for the diagnosis of DENV in clinics and hospitals in developing countries

Bacterial Microbiota Profiling in Gastritis without Helicobacter pylori Infection or Non-Steroidal Anti-Inflammatory Drug Use

Recent 16S ribosomal RNA gene (rRNA) molecular profiling of the stomach mucosa revealed a surprising complexity of microbiota. Helicobacter pylori infection and non-steroidal anti-inflammatory drug (NSAID) use are two main contributors to gastritis and peptic ulcer. However, little is known about the association between other members of the stomach microbiota and gastric diseases. In this study, cloning and sequencing of the 16S rRNA was used to profile the stomach microbiota from normal and gastritis patients. One hundred and thirty three phylotypes from eight bacterial phyla were identified. The stomach microbiota was found to be closely adhered to the mucosa. Eleven Streptococcus phylotypes were successfully cultivated from the biopsies. One to two genera represented a majority of clones within any of the identified phyla. We further developed two real-time quantitative PCR assays to quantify the relative abundance of the Firmicutes phylum and the Streptococcus genus. Significantly higher abundance of the Firmicutes phylum and the Streptococcus genus within the Firmicutes phylum was observed in patients with antral gastritis, compared with normal controls. This study suggests that the genus taxon level can largely represent much higher taxa such as the phylum. The clinical relevance and the mechanism underlying the altered microbiota composition in gastritis require further functional studies

Efficacy of Wolbachia-mediated sterility to suppress dengue: a synthetic control study

In a study conducted in Singapore, a country prone to dengue outbreaks due to its climate and urban population, researchers examined the effectiveness of releasing male Aedes aegypti mosquitoes infected with Wolbachia (wAlbB strain) to reduce dengue transmission. These infected males, when mating with wild-type females, produced non-viable eggs, leading to vector suppression. Extensive field trials involving over 600,000 residents in four townships were conducted from 2018 to 2022. The results showed a 57% decline in total dengue incidence and a 64% decline in clustered dengue incidence. This approach offers promise for large-scale dengue control in regions facing rising dengue cases, providing a critical solution in combating the disease