228 research outputs found
Retraction Notice of the Article: The DYRK-family kinase Pom1 phosphorylates the F-BAR protein Cdc15 to prevent division at cell poles
Division site positioning is critical for both symmetric and asymmetric cell divisions. In many organisms, positive and negative signals cooperate to position the contractile actin ring for cytokinesis. In rod-shaped fission yeast Schizosaccharomyces pombe cells, division at midcell is achieved through positive Mid1/anillin-dependent signaling emanating from the central nucleus and negative signals from the dual-specificity tyrosine phosphorylation-regulated kinase family kinase Pom1 at the cell poles. In this study, we show that Pom1 directly phosphorylates the F-BAR protein Cdc15, a central component of the cytokinetic ring. Pom1-dependent phosphorylation blocks Cdc15 binding to paxillin Pxl1 and C2 domain protein Fic1 and enhances Cdc15 dynamics. This promotes ring sliding from cell poles, which prevents septum assembly at the ends of cells with a displaced nucleus or lacking Mid1. Pom1 also slows down ring constriction. These results indicate that a strong negative signal from the Pom1 kinase at cell poles converts Cdc15 to its closed state, destabilizes the actomyosin ring, and thus promotes medial septation
Cosmic Rays during BBN as Origin of Lithium Problem
There may be non-thermal cosmic rays during big-bang nucleosynthesis (BBN)
epoch (dubbed as BBNCRs). This paper investigated whether such BBNCRs can be
the origin of Lithium problem or not. It can be expected that BBNCRs flux will
be small in order to keep the success of standard BBN (SBBN). With favorable
assumptions on the BBNCR spectrum between 0.09 -- 4 MeV, our numerical
calculation showed that extra contributions from BBNCRs can account for the
Li abundance successfully. However Li abundance is only lifted an order
of magnitude, which is still much lower than the observed value. As the
deuteron abundance is very sensitive to the spectrum choice of BBNCRs, the
allowed parameter space for the spectrum is strictly constrained. We should
emphasize that the acceleration mechanism for BBNCRs in the early universe is
still an open question. For example, strong turbulent magnetic field is
probably the solution to the problem. Whether such a mechanism can provide the
required spectrum deserves further studies.Comment: 34 pages, 21 figures, published versio
Cluster Monte Carlo study of multi-component fluids of the Stillinger-Helfand and Widom-Rowlinson type
Phase transitions of fluid mixtures of the type introduced by Stillinger and
Helfand are studied using a continuum version of the invaded cluster algorithm.
Particles of the same species do not interact, but particles of different types
interact with each other via a repulsive potential. Examples of interactions
include the Gaussian molecule potential and a repulsive step potential.
Accurate values of the critical density, fugacity and magnetic exponent are
found in two and three dimensions for the two-species model. The effect of
varying the number of species and of introducing quenched impurities is also
investigated. In all the cases studied, mixtures of -species are found to
have properties similar to -state Potts models.Comment: 25 pages, 5 figure
Probing the Environment with Galaxy Dynamics
I present various projects to study the halo dynamics of elliptical galaxies.
This allows one to study the outer mass and orbital distributions of
ellipticals in different environments, and the inner distributions of groups
and clusters themselves.Comment: 5 pages, 2 figs, to appear in Proc. ESO Workshop, Groups of Galaxies
in the Nearby Universe (5-9 Dec 2005), eds. I. Saviane, V. Ivanov & J.
Borissova (Springer-Verlag
Spinor condensates and light scattering from Bose-Einstein condensates
These notes discuss two aspects of the physics of atomic Bose-Einstein
condensates: optical properties and spinor condensates. The first topic
includes light scattering experiments which probe the excitations of a
condensate in both the free-particle and phonon regime. At higher light
intensity, a new form of superradiance and phase-coherent matter wave
amplification were observed. We also discuss properties of spinor condensates
and describe studies of ground--state spin domain structures and dynamical
studies which revealed metastable excited states and quantum tunneling.Comment: 58 pages, 33 figures, to appear in Proceedings of Les Houches 1999
Summer School, Session LXXI
Exact diagonalization of the generalized supersymmetric t-J model with boundaries
We study the generalized supersymmetric model with boundaries in three
different gradings: FFB, BFF and FBF. Starting from the trigonometric R-matrix,
and in the framework of the graded quantum inverse scattering method (QISM), we
solve the eigenvalue problems for the supersymmetric model. A detailed
calculations are presented to obtain the eigenvalues and Bethe ansatz equations
of the supersymmetric model with boundaries in three different
backgrounds.Comment: Latex file, 32 page
Reimagining the potential of Earth observations for ecosystem service assessments
The benefits nature provides to people, called ecosystem services, are increasingly recognized and accounted for in assessments of infrastructure development, agricultural management, conservation prioritization, and sustainable sourcing. These assessments are often limited by data, however, a gap with tremendous potential to be filled through Earth observations (EO), which produce a variety of data across spatial and temporal extents and resolutions. Despite widespread recognition of this potential, in practice few ecosystem service studies use EO. Here, we identify challenges and opportunities to using EO in ecosystem service modeling and assessment. Some challenges are technical, related to data awareness, processing, and access. These challenges require systematic investment in model platforms and data management. Other challenges are more conceptual but still systemic; they are byproducts of the structure of existing ecosystem service models and addressing them requires scientific investment in solutions and tools applicable to a wide range of models and approaches. We also highlight new ways in which EO can be leveraged for ecosystem service assessments, identifying promising new areas of research. More widespread use of EO for ecosystem service assessment will only be achieved if all of these types of challenges are addressed. This will require non-traditional funding and partnering opportunities from private and public agencies to promote data exploration, sharing, and archiving. Investing in this integration will be reflected in better and more accurate ecosystem service assessments worldwide
- …