67 research outputs found
The 3D Structure of N132D in the LMC: A Late-Stage Young Supernova Remnant
We have used the Wide Field Spectrograph (WiFeS) on the 2.3m telescope at
Siding Spring Observatory to map the [O III] 5007{\AA} dynamics of the young
oxygen-rich supernova remnant N132D in the Large Magellanic Cloud. From the
resultant data cube, we have been able to reconstruct the full 3D structure of
the system of [O III] filaments. The majority of the ejecta form a ring of
~12pc in diameter inclined at an angle of 25 degrees to the line of sight. We
conclude that SNR N132D is approaching the end of the reverse shock phase
before entering the fully thermalized Sedov phase of evolution. We speculate
that the ring of oxygen-rich material comes from ejecta in the equatorial plane
of a bipolar explosion, and that the overall shape of the SNR is strongly
influenced by the pre-supernova mass loss from the progenitor star. We find
tantalizing evidence of a polar jet associated with a very fast oxygen-rich
knot, and clear evidence that the central star has interacted with one or more
dense clouds in the surrounding ISM.Comment: Accepted for Publication in Astrophysics & Space Science, 18pp, 8
figure
Wind-Blown Bubbles around Evolved Stars
Most stars will experience episodes of substantial mass loss at some point in
their lives. For very massive stars, mass loss dominates their evolution,
although the mass loss rates are not known exactly, particularly once the star
has left the main sequence. Direct observations of the stellar winds of massive
stars can give information on the current mass-loss rates, while studies of the
ring nebulae and HI shells that surround many Wolf-Rayet (WR) and luminous blue
variable (LBV) stars provide information on the previous mass-loss history. The
evolution of the most massive stars, (M > 25 solar masses), essentially follows
the sequence O star to LBV or red supergiant (RSG) to WR star to supernova. For
stars of mass less than 25 solar masses there is no final WR stage. During the
main sequence and WR stages, the mass loss takes the form of highly supersonic
stellar winds, which blow bubbles in the interstellar and circumstellar medium.
In this way, the mechanical luminosity of the stellar wind is converted into
kinetic energy of the swept-up ambient material, which is important for the
dynamics of the interstellar medium. In this review article, analytic and
numerical models are used to describe the hydrodynamics and energetics of
wind-blown bubbles. A brief review of observations of bubbles is given, and the
degree to which theory is supported by observations is discussed.Comment: To be published as a chapter in 'Diffuse Matter from Star Forming
Regions to Active Galaxies' - A volume Honouring John Dyson. Eds. T. W.
Harquist, J. M. Pittard and S. A. E. G. Falle. 22 pages, 12 figure
New insights into the genetic etiology of Alzheimer's disease and related dementias
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
Book reviews : Shaw, G. and Tipper, A. 1988: British directories: a bibliography and guide to directories published in England and Wales 1850-1950 and Scotland 1773-1950. Leicester: Leicester University Press. i + 440 pp. £47.50 cloth
Book reviews : Atkins, P.J. 1990: The directories of London 1677-1977. London: Cassell and Mansell. xii + 740 pp. £65.00 cloth. ISBN: 0 720 12063 2
Biosynthesis of actinomycin D : Purification and properties of an enzyme which activates L-valine
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