Association of HIV diversification with duration of HIV infection and other factors (paired analysis).

<p>Association of HIV diversification with duration of HIV infection and other factors (paired analysis).</p

Association of HIV diversity with CD4 cell count and HIV viral load in men who were HIV infected at enrollment.

<p>Scatterplots show the relationship between high resolution melting (HRM) score with HIV viral load and CD4 cell count for men who were HIV infected at enrollment; <i>p</i>-values <0.05 are shown.</p

Study cohort.

<p>The high resolution melting (HRM) diversity assay was performed for a subset of men in HPTN 061. Data was analyzed for men who had HRM scores determined for all six regions in the HIV genome (shaded boxes).</p

Multivariate analysis of HIV diversity at study enrollment.

<p>Multivariate analysis of HIV diversity at study enrollment.</p

HRM scores for men who were HIV infected at enrollment and men who seroconverted during the HPTN 061 study.

<p>Box and whisker plots show the distribution of high resolution melting (HRM) scores for six regions in the HIV genome. Data are shown for men in different subgroups (acute infection at enrollment, recent infection at enrollment, non-recent infection at enrollment; seroconverters; see text). Symbols show the median (inner line), interquartile range (box), lower inner and upper outer fences (whiskers), and outliers (circles) for HRM scores. Univariate median regression analyses were used to compare HRM scores between the indicated groups; <i>p</i>-values for these comparisons are shown (*<i>p</i><0.05; **<i>p</i><0.01).</p

Summary of study participants.

<p>Summary of study participants.</p