646 research outputs found

    Three-dimensional interactive maps: theory and practice

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    Let the Judge Speak: Reconsidering the Role of Rehabilitation in Federal Sentencing

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    (Excerpt) This Note contends that the importance of rehabilitation as a valid and necessary principle of punishment is overlooked in Β§ 3582(a) of the SRA and further argues that a judge should be permitted to consider rehabilitation when deciding to sentence a defendant to a term of imprisonment, so long as rehabilitation is not a dominant factor in coming to that decision. Part I outlines the principles of punishment and the rise and decline of the rehabilitative system of punishment in the United States. It also discusses the importance of rehabilitation and how society could benefit from a system that does not leave rehabilitation by the wayside. Part II discusses the Supreme Court’s ruling in Tapia v. United States and the resulting circuit split concerning the degree to which rehabilitation can be considered when sentencing a criminal defendant to a term of imprisonment in accordance with Β§ 3553(a)(2)(D) and Β§ 3582(a) of the SRA. Finally, Part III recommends that the Supreme Court resolve the circuit split by adopting the Fifth Circuit’s additional justification and dominant factor tests, or alternatively, that Congress amend Β§ 3582(a) so as to permit judges to consider and talk about potential rehabilitation, without fear of being overruled for such discussions, when sentencing a defendant to prison

    Let the Judge Speak: Reconsidering the Role of Rehabilitation in Federal Sentencing

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    (Excerpt) This Note contends that the importance of rehabilitation as a valid and necessary principle of punishment is overlooked in Β§ 3582(a) of the SRA and further argues that a judge should be permitted to consider rehabilitation when deciding to sentence a defendant to a term of imprisonment, so long as rehabilitation is not a dominant factor in coming to that decision. Part I outlines the principles of punishment and the rise and decline of the rehabilitative system of punishment in the United States. It also discusses the importance of rehabilitation and how society could benefit from a system that does not leave rehabilitation by the wayside. Part II discusses the Supreme Court’s ruling in Tapia v. United States and the resulting circuit split concerning the degree to which rehabilitation can be considered when sentencing a criminal defendant to a term of imprisonment in accordance with Β§ 3553(a)(2)(D) and Β§ 3582(a) of the SRA. Finally, Part III recommends that the Supreme Court resolve the circuit split by adopting the Fifth Circuit’s additional justification and dominant factor tests, or alternatively, that Congress amend Β§ 3582(a) so as to permit judges to consider and talk about potential rehabilitation, without fear of being overruled for such discussions, when sentencing a defendant to prison

    ΠšΠΎΡ€Ρ‹ вывСтривания Π΄ΠΎΡŽΡ€ΡΠΊΠΈΡ… ΠΎΡ‚Π»ΠΎΠΆΠ΅Π½ΠΈΠΉ Π—Π°ΠΏΠ°Π΄Π½ΠΎ-Бибирской гСосинСклизы

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    Π”ΠΎΡŽΡ€ΡΠΊΠΈΠ΅ (вСндскиС, палСозойскиС) отлоТСния юго-восточной части Π—Π°ΠΏΠ°Π΄Π½ΠΎ-Бибирской гСосинСклизы ΠΏΡ€ΠΎΡˆΠ»ΠΈ прСобразования ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎ: Π΄ΠΈΠ°Π³Π΅Π½Π΅Π· ΠΈ ΠΏΠ΅Ρ€Π²ΠΈΡ‡Π½Ρ‹ΠΉ ΠΊΠ°Ρ‚Π°Π³Π΅Π½Π΅Π· Π²ΠΎ врСмя ΠΈ сразу послС окамСнСния; ΠΎΡ€ΠΎΠ³Π΅Π½Π½Ρ‹ΠΉ этап развития ΠΈ формирования ΠΊΠΎΡ€ вывСтривания Π² ΠΏΠ΅Ρ€ΠΌΠΈ-триасС; Π²Ρ‚ΠΎΡ€ΠΈΡ‡Π½ΠΎ-катагСнСтичСскиС прСобразования, начиная с ΡŽΡ€ΡΠΊΠΎΠ³ΠΎ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Π°. ΠšΠΎΡ€Ρ‹ вывСтривания Ρ€Π°Π·Π²ΠΈΡ‚Ρ‹ ΠΏΠΎ всСй ΠΏΠ»ΠΎΡ‰Π°Π΄ΠΈ Π²Ρ‹Ρ…ΠΎΠ΄Π° Π½Π° Π΄ΠΎΡŽΡ€ΡΠΊΡƒΡŽ ΠΏΠΎΠ²Π΅Ρ€Ρ…Π½ΠΎΡΡ‚ΡŒ палСозойских ΠΏΠΎΡ€ΠΎΠ΄ Π² Π²ΠΈΠ΄Π΅ ΠΌΠ°Π»ΠΎΠΌΠΎΡ‰Π½ΠΎΠΉ приповСрхностной Π·ΠΎΠ½Ρ‹ ΡƒΠ»ΡƒΡ‡ΡˆΠ΅Π½Π½Ρ‹Ρ… коллСкторских свойств, Π² Π²ΠΈΠ΄Π΅ крСмнисто-глинистых щСбнистых масс ΠΏΠΎ отлоТСниям Π°Π½Π°Π»ΠΎΠ³ΠΈΡ‡Π½ΠΎΠ³ΠΎ состава, Π° ΠΏΠΎ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½Π½Ρ‹ΠΌ эффузивам основного состава ΠΈ Ρ‚ΡƒΡ„Π°ΠΌ Ρ€Π°Π·Π²ΠΈΡ‚Ρ‹ бокситы, Π² Ρ‚ΠΎΠΌ числС ΠΏΠ΅Ρ€Π΅ΠΎΡ‚Π»ΠΎΠΆΠ΅Π½Π½Ρ‹Π΅. Π’ образованиях ΠΊΠΎΡ€Ρ‹ вывСтривания сформированы ΠΊΠΎΠ»Π»Π΅ΠΊΡ‚ΠΎΡ€Ρ‹, ΡΠΎΠ²ΠΎΠΊΡƒΠΏΠ½ΠΎΡΡ‚ΡŒ ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… имСнуСтся нСфтСгазоносный Π³ΠΎΡ€ΠΈΠ·ΠΎΠ½Ρ‚ Π·ΠΎΠ½Ρ‹ ΠΊΠΎΠ½Ρ‚Π°ΠΊΡ‚Π°. ГСомСтрия сформированных Π»ΠΎΠ²ΡƒΡˆΠ΅ΠΊ Π½Π΅Ρ„Ρ‚ΠΈ ΠΈ Π³Π°Π·Π° ΠΈΠΌΠ΅Π΅Ρ‚ Π»ΠΈΠ½Π΅ΠΉΠ½ΠΎ-Π²Ρ‹Ρ‚ΡΠ½ΡƒΡ‚ΡƒΡŽ ΠΏΠ»Π°Ρ‰Π΅ΠΎΠ±Ρ€Π°Π·Π½ΡƒΡŽ Ρ„ΠΎΡ€ΠΌΡƒ

    Overcoming barriers to a successful transition from pediatric to adult care

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    As life expectancy for people with cystic fibrosis (CF) has increased dramatically, so has the need for a guided, structured transition from pediatric to adult-focused care. A formalized transition program allows for seamless transfer of patients between providers, helping to ensure continuity of care, and avoid potential declines associated with inconsistent medical care. New CF Center guidelines issued by the CFF strongly recommend that each center establish a transition program for age-appropriate transition to an adult CF clinic. In this article, we explore the remaining barriers to establishing a transition program in a CF Center and offer examples of several successful models. We describe CFF-sponsored and other initiatives that exist to support centers in establishing a transition program and discuss the need for ongoing research in this area

    Klinische, radiologische und ganganalytische Ergebnisse nach endoprothetischem Kniegelenksersatz Attune vs. LCS

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    Als ein wesentlicher Parameter hat sich die Ganganalyse als ein objektives Instrument zu Beurteilung des Bewegungsablaufes etabliert. Ziel dieser Studie ist die Beurteilung des Attune-Implantates als Weiterentwicklung des LCS- Implantates, welches seit Jahren seinen Stellenwert auf dem Markt belegt hat, hinsichtlich Patientenzufriedenheit, klinische, radiologische und ganganalytische Aspekte. Methodik: In einer retrospektiven Vergleich Studie wurden 2015 bis 2016 in einem universitΓ€ren EPZmax 63 Patienten, bei denen bei primΓ€rer Gonarthrose ein OberflΓ€chenersatz in Balance Gap Technik implantiert worden ist, eingeschlossen. Die Parameter der Ganganalyse mit dem Knie TEP versorgten Patienten wurden denen einer gesunden Vergleichsgruppe von 50 Probanden gegenΓΌber gestellt. Es wurden 30 Patienten mit einer Attune-KTEP und 33 Patienten mit einer LCS-KTEP versorgt. Die Nachbeobachtungszeit betrug mindestens 1 Jahr. Die Ganganalysen wurden mit dem 3D-Bewegungsanalysesystem Vicon (Vicon, Oxford, GB) mit 10 Infrarotkameras mit 3 Kraftmessplatten durchgefΓΌhrt. PrΓ€- und postoperativ wurden eine Ganzbeinaufnahme und Knie seitlich angefertigt. Zur klinischen Evaluation wurden die folgenden Scores erhoben: Knee Society Score (KSS), Forgotten Joint Score (FSJ 12), WOMAC und Patientenzufriedenheit-Test. Ergebnisse und Schlussfolgerung: Der Einsatz von Attune Kniesystems fΓΌhrt zu einem physiologischeren Gangbild und besserem Bewegungsumfang gegenΓΌber dem LCS Kniesystem. Der Bewegungsumfang war in der Attune Gruppe mit 129Β°+- 16Β° signifikant hΓΆher als in der LCS Gruppe 109Β°+- 15Β°, p<0,001. Bei den 29 FΓ€llen signifikanter Unterschiede lagen die Mittelwerte der Parameter fΓΌr Attune 27 mal nΓ€her an den Werten der Gesunden und nur 2 mal fΓΌr die Gruppe LCS. Diese Studie konnte keine besseren klinischen und/oder radiologischen Ergebnisse des neuen Prothesendesign des Attune Kniesystems aufzeigen. Auch eine bessere Patientenzufriedenheit als beim LCS Kniesystem fand sich nicht

    ЗакономСрности синтСза нанодиспСрсных оксидов ΠΌΠ΅Π΄ΠΈ элСктролизом Π½Π° ΠΏΠ΅Ρ€Π΅ΠΌΠ΅Π½Π½ΠΎΠΌ Ρ‚ΠΎΠΊΠ΅ Π² растворС Ρ‰Π΅Π»ΠΎΡ‡ΠΈ

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    Показана Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡ‚ΡŒ получСния оксидов ΠΌΠ΅Π΄ΠΈ с высокой ΠΏΠ»ΠΎΡ‰Π°Π΄ΡŒΡŽ ΡƒΠ΄Π΅Π»ΡŒΠ½ΠΎΠΉ повСрхности элСктролизом мСталличСской ΠΌΠ΅Π΄ΠΈ с использованиСм ΠΏΠ΅Ρ€Π΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ Ρ‚ΠΎΠΊΠ° ΠΏΡ€ΠΎΠΌΡ‹ΡˆΠ»Π΅Π½Π½ΠΎΠΉ частоты. Π˜Π·ΡƒΡ‡Π΅Π½Ρ‹ ΠΏΠ°Ρ€Π°ΠΌΠ΅Ρ‚Ρ€Ρ‹, ΠΎΠΊΠ°Π·Ρ‹Π²Π°ΡŽΡ‰ΠΈΠ΅ влияниС Π½Π° ΡΠΊΠΎΡ€ΠΎΡΡ‚ΡŒ образования оксидов. ΠžΠΏΡ€Π΅Π΄Π΅Π»Ρ‘Π½ Ρ„Π°Π·ΠΎΠ²Ρ‹ΠΉ состав ΠΈ характСристики пористой структуры ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ² элСктросинтСза Π² зависимости ΠΎΡ‚ Ρ€Π΅ΠΆΠΈΠΌΠΎΠ² провСдСния процСсса

    Domestic violence: firearm seizures and lethality assessments: enhancing the police response

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    Recommends that police procedures in cases of domestic violence include seizing prohibited offender firearms

    Experimental studies on shear connection between steel and lightweight concrete using studs

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    This contribution describes Standard Push-Out Tests carried out at University of Minho (UM) and the Single Push-Out Tests performed at the Institute of Structural Concrete at RWTH Aachen University using high strength lightweight concrete (HSLWC). The test configuration follows the EC4 recommendations and repeats some dispositions referred by other authors. The experimental studies carried out at RWTH and UM include tests on studs with diameters of 19, 22 and 25 mm and also tests on studs of 19 mm diameter, which are grouped in pairs. The purpose of the experiments conducted is to determine the load-bearing capacity as well as the deformation capacity of commonly used headed shear stud when using high strength lightweight concrete. The results from these tests are compared to those from the tests performed with high strength normal weight concrete (NWC)

    Toll-like Receptor-4 Regulation of Hepatic Cyp3a11 Metabolism in a Mouse Model of LPS-induced CNS Inflammation

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    Central nervous system (CNS) infection and inflammation severely reduce the capacity of cytochrome P-450 metabolism in the liver. We developed a mouse model to examine the effects of CNS inflammation on hepatic cytochrome P-450 metabolism. FVB, C57BL/6, and C3H/HeouJ mice were given Escherichia coli LPS (2.5 ΞΌg) by intracerebroventricular (ICV) injection. The CNS inflammatory response was confirmed by the elevation of TNF-Ξ± and/or IL-1Ξ² proteins in the brain. In all mouse strains, LPS produced a 60–70% loss in hepatic Cyp3a11 expression and activity compared with saline-injected controls. Adrenalectomy did not prevent the loss in Cyp3a11 expression or activity, thereby precluding the involvement of the hypothalamic-adrenal-pituitary axis. Endotoxin was detectable (1–10 ng/ml) in serum between 15 and 120 min after ICV dosing of 2.5 ΞΌg LPS. Peripheral administration of 2.5 ΞΌg LPS by intraperitoneal injection produced similar serum endotoxin levels and a similar loss (60%) in Cyp3a11 expression and activity in the liver. The loss of Cyp3a11 in response to centrally or peripherally administered LPS could not be evoked in Toll-like receptor-4 (TLR4)-mutant (C3H/ HeJ) mice, indicating that TLR4 signaling pathways are directly involved in the enzyme loss. In summary, we conclude that LPS is transferred from the brain to the circulation in significant quantities in a model of CNS infection or inflammation. Subsequently, LPS that has reached the circulation stimulates a TLR4-dependent mechanism in the periphery, evoking a reduction in Cyp3a11 expression and metabolism in the liver
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