2 research outputs found
Development of a lisinopril (5 mg) formulation
Se describe el desarrollo de diferentes variantes tecnol贸gicas de tabletas de Lisinopril (5 mg de dosis). Se evalu贸 el efecto de diferentes excipientes sobre la calidad tecnol贸gica de los comprimidos a partir de un dise帽o de experimento 22. Se describe un estudio comparativo de dos procedimientos de elaboraci贸n: compresi贸n directa y granulaci贸n h煤meda. El estudio demostr贸 que es factible la elaboraci贸n de este producto por ambos m茅todos.Development of different formulations of lisinopril (5 mg) is described. Factorial experimental design (22) was employed in order to evaluate the effect of different excipients on the quality of tablets. A comparative study for two manufactured process is described. Obtained results show that direct compression and wet granulation process can be used for development of Lisinopril 5 mg tablets.Colegio de Farmac茅uticos de la Provincia de Buenos Aire
Development of a lisinopril (5 mg) formulation
Se describe el desarrollo de diferentes variantes tecnol贸gicas de tabletas de Lisinopril (5 mg de dosis). Se evalu贸 el efecto de diferentes excipientes sobre la calidad tecnol贸gica de los comprimidos a partir de un dise帽o de experimento 22. Se describe un estudio comparativo de dos procedimientos de elaboraci贸n: compresi贸n directa y granulaci贸n h煤meda. El estudio demostr贸 que es factible la elaboraci贸n de este producto por ambos m茅todos.Development of different formulations of lisinopril (5 mg) is described. Factorial experimental design (22) was employed in order to evaluate the effect of different excipients on the quality of tablets. A comparative study for two manufactured process is described. Obtained results show that direct compression and wet granulation process can be used for development of Lisinopril 5 mg tablets.Colegio de Farmac茅uticos de la Provincia de Buenos Aire