Ginzburg-Landau functional for nearly antiferromagnetic perfect and disordered Kondo lattices

Interplay between Kondo effect and trends to antiferromagnetic and spin glass ordering in perfect and disordered bipartite Kondo lattices is considered. Ginzburg-Landau equation is derived from the microscopic effective action written in three mode representation (Kondo screening, antiferromagnetic correlations and spin liquid correlations). The problem of local constraint is resolved by means of Popov-Fedotov representation for localized spin operators. It is shown that the Kondo screening enhances the trend to a spin liquid crossover and suppresses antiferromagnetic ordering in perfect Kondo lattices and spin glass ordering in doped Kondo lattices. The modified Doniach's diagram is constructed, and possibilities of going beyond the mean field approximation are discussed.Comment: 18 pages, RevTeX, 7 EPS figures include

Mutant p53 as a guardian of the cancer cell

Forty years of research have established that the p53 tumor suppressor provides a major barrier to neoplastic transformation and tumor progression by its unique ability to act as an extremely sensitive collector of stress inputs, and to coordinate a complex framework of diverse effector pathways and processes that protect cellular homeostasis and genome stability. Missense mutations in the TP53 gene are extremely widespread in human cancers and give rise to mutant p53 proteins that lose tumor suppressive activities, and some of which exert trans-dominant repression over the wild-type counterpart. Cancer cells acquire selective advantages by retaining mutant forms of the protein, which radically subvert the nature of the p53 pathway by promoting invasion, metastasis and chemoresistance. In this review, we consider available evidence suggesting that mutant p53 proteins can favor cancer cell survival and tumor progression by acting as homeostatic factors that sense and protect cancer cells from transformation-related stress stimuli, including DNA lesions, oxidative and proteotoxic stress, metabolic inbalance, interaction with the tumor microenvironment, and the immune system. These activities of mutant p53 may explain cancer cell addiction to this particular oncogene, and their study may disclose tumor vulnerabilities and synthetic lethalities that could be exploited for hitting tumors bearing missense TP53 mutations

Publisher Correction: Fundamental social motives measured across forty-two cultures in two waves.

This is the final version. Available from Nature Research via the DOI in this record.

Fundamental social motives measured across forty-two cultures in two waves.

This is the final version. Available from Nature Research via the DOI in this record. Code availability: All code used to process and visualize the data, including information on software packages used, is freely available in the OSF projectHow does psychology vary across human societies? The fundamental social motives framework adopts an evolutionary approach to capture the broad range of human social goals within a taxonomy of ancestrally recurring threats and opportunities. These motives-self-protection, disease avoidance, affiliation, status, mate acquisition, mate retention, and kin care-are high in fitness relevance and everyday salience, yet understudied cross-culturally. Here, we gathered data on these motives in 42 countries (N = 15,915) in two cross-sectional waves, including 19 countries (N = 10,907) for which data were gathered in both waves. Wave 1 was collected from mid-2016 through late 2019 (32 countries, N = 8,998; 3,302 male, 5,585 female; Mage = 24.43, SD = 7.91). Wave 2 was collected from April through November 2020, during the COVID-19 pandemic (29 countries, N = 6,917; 2,249 male, 4,218 female; Mage = 28.59, SD = 11.31). These data can be used to assess differences and similarities in people's fundamental social motives both across and within cultures, at different time points, and in relation to other commonly studied cultural indicators and outcomes.National Science FoundationFAPESP (São Paulo Research Foundation)Czech Science FoundationCzech Science FoundationInstitute of Psychology, Czech Academy of SciencesUniversidad de la FronteraAberystwyth Universit

Influence of boron on the magnetic and transport properties of FeZr amorphous and nanocrystalline alloys

The magnetic properties and electrical resistivity of amorphous and nanocrystalline FeZr and FeZrB(Cu) alloys are compared in a wide range of temperatures (4 to 1000 K). The addition of boron increases the Curie temperature of the alloys and induces a broad minimum in the resistivity vs temperatures. A first step of crystallization occurs around 700 K in all the alloys, giving rise to α -Fe crystallites of very small size. Small amounts of boron greatly influence the exchange interactions, enhancing the ferromagnetic character of these compounds

Electron-electron interaction, quantum interference and spin fluctuation effects in the resistivity of Fe-rich Fe-Zr metallic glasses

Electrical resistivity (ρ) measurements have been performed in various temperature ranges on different batches of samples with nominal composition x = 0 and 1 in the amorphous alloy series Fe90+xZr10-x. An elaborate data analysis brings out clearly the actual functional dependences of ρ on temperature (T) in different temperature ranges. The results of this analysis, when discussed in the light of existing theories, permit identification of the dominant mechanisms of electrical transport in different temperature regions as electron-diffuson (non-propagating longitudinal spin fluctuations) scattering for T≤10 K, enhanced electron-electron interaction (EEI) effects in the range 10 K ≤T≤25 K and quantum interference (QI) effects, electron-phonon (e-ph) as well as electron-spin fluctuations scattering in different temperature ranges above 25 K. EEI and QI contributions to ρ, in turn, yield fairly accurate values for the diffusion constant (that obey the Einstein relation) and the dephasing time. Out of the inelastic scattering processes such as e-ph scattering, spin-orbit scattering and spin-flip scattering that destroy phase coherence, e-ph scattering seems to be the most effective dephasing mechanism. Dephasing persists to temperatures well above the Curie point and Debye temperature in the amorphous alloys in question