Viability of the Raw Cotton Production in Spain After the Decoupling of the Subsidies

Considering the latest reform of the EU's Cotton Regulation of 29th April 2004, which will come into force in the 2006/07 season, we analyse its impact on the cotton production sector of Andalusia. The decoupling of subsidies implies that producers will be entitled to 65 percent of the amount received in the reference period (three years) irrespective of the crop chosen to grow. The remaining 35 percent (slightly higher) is paid as cotton are a payment. In this research, first from a survey carried out in 2004 we obtained six groups of producers using fact or analysis and cluster analysis. Then, based on this characterization, we assess the impact of two policy scenarios: (a) the implementation of the reform without any additional measures, and (b) the addition of a complementary environmentally based area payment plus the modulation of the decoupled subsidy up to 50 percent according to raw cotton quality. In the first scenario most producers would reduce the use of inputs to a minimum and leave the raw cotton in the fields. In the second scenario the production of cotton would shift from conventional toward Integrated Production with a reduction of 30% with respect to the current hectarage.Cotton, Spain, Mid-Term Reform, Simulation, Multi-Criteria Decision Making, Agricultural and Food Policy, Crop Production/Industries,

One hundred of cells generations connect the resistance to drugs and the replicative aging mechanisms

There are researchs that reveal a relationship between acquired resistance to antineoplastic drugs and aging. Therefore, the identification of genes involved in senescence could have a potential therapeutic utility for the prediction and/or prevention of resistance to antineoplastic drugs. The aim of this work is to study the relationship between replicative aging and acquired resistance to Cisplatin and Bleomycin in the yeast Saccharomyces cerevisiae.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Proteomic analysis in wild type and cisplatin resistant yeast strain of saccharomyces cerevisiae

Research carried out in oncology has allowed the identification and characterization of molecular markers of resistance to antineoplastic drugs. It supposes a great advance and allows the administration of customized chemotherapies to patients. The aim of this work is to carry out a proteomic analysis in the wild type strain and cisplatin resistant strain of Saccharomyces cerevisiae in order to look for possible markers of resistance, as well as the mechanisms involved.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

New markers of bleomycin resistance

Resistance to chemotherapy is one of the main problems of this type of therapy. Studies carried out determine the usefulness of predictive biomarkers to improve this treatment. The aim of this work is to carry out a proteomic analysis in the wild type strain and bleomycin resistant strain of Saccharomyces cerevisiae in order to look for possible markers of resistance, as well as the mechanisms involved.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Mechanisms of cross resistance between cisplatin and bleomycin in saccharomyces cerevisiae

Tumor cells can simultaneously acquire resistance against a diverse group of drugs. This phenomenon is called pleotropic resistance or multidrug resistance. This mechanism could explain the tumor resistance observed in chemotherapy treatments with multiple agents. The aim of this work is to study possible mechanisms of cross resistance between Cisplatin and Bleomycin in Saccharomyces cerevisiae.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

3D Segmentation Method for Natural Environments based on a Geometric-Featured Voxel Map

This work proposes a new segmentation algorithm for three-dimensional dense point clouds and has been specially designed for natural environments where the ground is unstructured and may include big slopes, non-flat areas and isolated areas. This technique is based on a Geometric-Featured Voxel map (GFV) where the scene is discretized in constant size cubes or voxels which are classified in flat surface, linear or tubular structures and scattered or undefined shapes, usually corresponding to vegetation. Since this is not a point-based technique the computational cost is significantly reduced, hence it may be compatible with Real-Time applications. The ground is extracted in order to obtain more accurate results in the posterior segmentation process. The scene is split into objects and a second segmentation in regions inside each object is performed based on the voxel’s geometric class. The work here evaluates the proposed algorithm in various versions and several voxel sizes and compares the results with other methods from the literature. For the segmentation evaluation the algorithms are tested on several differently challenging hand-labeled data sets using two metrics, one of which is novel.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Optimizing Scan Homogeneity for Building Full-3D Lidars based on Rotating a Multi-Beam Velodyne Rangefinder

Multi-beam lidar (MBL) scanners are compact, light, and accessible 3D sensors with high data rates, but they offer limited vertical resolution and field of view (FOV). Some recent robotics research has profited from the addition of a degree-of-freedom (DOF) to an MBL to build rotating multi-beam lidars (RMBL) that can achieve high-resolution scans with full spherical FOV. In a previous work, we offered a methodology to analyze the complex 3D scan measurement distributions produced by RMBLs with a rolling DOF and no pitching. In this paper, we investigate the effect of introducing constant pitch angles in the construction of the RMBLs with the purpose of finding a kinematic configuration that optimizes scan homogeneity with a spherical FOV. To this end, we propose a scalar index of 3D sensor homogeneity that is based on the spherical formulation of Ripley's K function. The optimization is performed for the widely used Puck (VLP-16) and HDL-32 sensors by Velodyne.This work was partially funded by the Spanish project {DPI2015-65186-R}. The publication has received support from Universidad de Málaga, Campus de Excelencia Andalucía Tech

Resistance to bleomycin increases the chronological life of cells

The identification of genes involved in chronological aging could have a potential utility as molecular markers in the chemotherapy treatment of cancer. The aim of this work is to study the relationship between the chronological aging and the resistance to Bleomycin for the purpose of establish the basic interactions between these phenomenons for further investigation of molecular markers.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Resistance acquisition after seven cycles of in vitro bleomycin exposure

Bleomycin is an antineoplastic drug that causes DNA damage by intra- and inter-strand crosslink and DNA strand breaks. This drug is used to treat several types of cancer. The aim of this work is to study the effect of Bleomycin on S. cerevisiae cells and select bleomycin-resistant cells to study the process of resistance acquisition to establish new protocols in in vitro drugs exposure.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Relationship between chronological aging and acquired resistance to cisplatin in the yeast saccharomyces cerevisiae

The Sir2 gene is associated with an increase in longevity in yeasts, worms, flies and rodents. The human homolog, Sirt1, is also involved in longevity, by inhibiting cellular senescence. Studies carry out in tumor cells of neuroblastoma, osteosarcoma, breast and ovary, resistant and sensitive to antineoplastic drugs, suggest that the increase of Sirt1 expression may represent a general phenomenon associated with resistance to chemotherapy, independent of cell type or drug used to induce resistance. Thus, after analyzing tumor biopsies after treating patients with chemotherapy, high amounts of Sirt1 have been observed. The aim of this work is to study the relationship between chronological aging and acquired resistance to Cisplatin in the yeast Saccharomyces cerevisiae.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech