Síndromes Auto - Inflamatórias

As síndromes auto-inflamatórias são constituídas por um grupo heterogéneo de patologias isoladas e caracterizadas ao longo dos últimos 15 anos, graças aos avanços marcados no conhecimento do genoma humano e ao desenvolvimento de técnicas laboratoriais que permitiram identificar, de forma segura e reprodutível, os genes responsáveis pelas várias doenças incluídas sob esta designação comum. Em todas estas doenças e síndromes existem episódios recorrentes de febre e inflamação, localizada ou sistémica, sem o envolvimento de agentes infecciosos ou quaisquer tipo de mecanismos auto-imunes. Neste trabalho, além da elaboração de uma classificação possível das síndromes auto-inflamatórias, dedicaremos especial atenção às síndromes periódicas associadas à criopirina (CAPS), que podem constituir importante causa de diagnóstico diferencial com a forma sistémica de artrite idiopática juvenil (AIJ), com a qual partilham numerosas características clínicas comuns

Efeito de procedências de Eucalyptus camaldulensis sobre os teores de nutrientes e de carbono orgânico do solo no cerrado.

RESUMO: O objetivo deste trabalho foi avaliar o efeito do plantio de eucalipto nos teores de nutrientes e de carbono orgânico do solo em comparação com uma área virgem de Cerrado. Foram coletadas e analisadas amostras de solo até 1 m de profundidade em um experimento de procedências de Eucalyptus camaldulensis e em uma área adjacente de Cerrado, na mesma posição topográfica, em Planaltina, Distrito Federal. O solo é Latossolo Vermelho, argiloso (55% de argila, 23% de silte, 2% de areia grossa e 20% de areia fina) e distrófico. Na ocasião do plantio, o eucalipto foi adubado com 40 g de sulfato de amônio, 60 g de superfosfato triplo, 20% decloreto de potássio, 2 g de sulfato de zinco, 3 g de bórax e 500 g de calcário dolomítico por cova. As procedências avaliadas foram: 10911 de Emu Creek, Queensland; 9856 de Agnew Road, West Australian; e 10557 de Kimberley Area, West Australian. O pH teve crescimento linear com o aumento da profundidade, porém, nas áreas reflorestadas com a procedência 9856, esse aumento foi proporcionalmente maior que o observado para as áreas com as outras procedências. O teor de magnésio foi menor na área com Cerrado nativo em comparação com as reflorestadas com as procedências 9856 e 10911. O plantio de eucalipto, comparado com o Cerrado, elevou os teores de potássio e de carbono orgânico, sobretudo, nas camadas superficiais do solo. Os teores de fósforo, de potássio, de cálcio, de magnésio e de carbono orgânico no solo diminuíram com o aumento da profundidade, tanto nas áreas reflorestadas como em áreas de Cerrado. ABSTRACT: The objective of this paper was to evaluate the effect of Eucalyptus camaldulensis plantation on soil carbon and nutrients contents in comparasion to virgin area of Cerrado. Soil samples of soil were collected down to 1 m depth in the soil profile in an experiment composed by three Eucalyptus camaldulensis provenances and an adjacent area of Cerrado. Soil was classified as dystrophic Claying Red Latossol composed by 52% of clay, 13% of silt, 3% of coarse sand and 25% of fine sand. At seedling time fertilizers were applied at the rate: 40 g of ammonium, 60 g of triple superphosphate, 20 g of potassium chloride, 2 g zinc sulphate, 3 g of borax and 500 g dolomitic lime for plant per planting pit. Provenances from Emu Creek, Queensland (10911); Agnew Road, West Australian, (9856) and Kimberley Area, West Australian (10557) were evaluated. The pH increased linearly as depth increased, however for provenace 9856 this increase was proportionally higher than the others. The magnesium content was lower in Cerrado than in reforested areas with provenances 9856 and 10911. Eucalypt plantation, compared with the Cerrado vegetation, increased organic carbon and potassium contents in the upper soil layers. Soil phosphorus, potassium, calcium, magnesium and organic carbon contents decreased as depth increased in both reforested ares and in the Cerrado.bitstream/CPAC-2009/26774/1/bolpd_142.pd

Negative Even Grade mKdV Hierarchy and its Soliton Solutions

In this paper we provide an algebraic construction for the negative even mKdV hierarchy which gives rise to time evolutions associated to even graded Lie algebraic structure. We propose a modification of the dressing method, in order to incorporate a non-trivial vacuum configuration and construct a deformed vertex operator for $\hat{sl}(2)$, that enable us to obtain explicit and systematic solutions for the whole negative even grade equations

Hydro- and morphodynamic impacts of sea level rise: The Minho estuary case study

The understanding and anticipating of climate change impacts is one of the greatest challenges for humanity. It is already known that, until the end of the 21st century, the mean sea level (MSL) will rise at a global scale, but its effects at the local scale need to be further analyzed. In this context, a numerical modelling tool and a methodological approach for the river Minho estuary (NW of the Iberian Peninsula) are presented, to predict possible consequences of local MSL rise, considering the greenhouse emission scenarios RCP 4.5 and RCP 8.5. Hydrodynamic and morphodynamic impacts were analyzed considering several driving factors, such as tides, sea level rise, storm surge, wave set-up, and different river flood peak discharges, taking into account their probabilities of occurrence. The model was calibrated using in-situ data and a data assimilation tool, the OpenDA, which automates this process, allowing to reach reliable results in a considerably short time when compared with traditional techniques. The results forecast that the predicted MSL rise will reduce the flow velocity magnitude and the sediment transport into the coastal platform but will aggravate the inundation risks along the estuarine banks. In the worst scenario (RCP 8.5) the water level near the river mouth of the estuary is expected to rise 0.20 m for 50 years return period ocean water rising, and 0.60 m for 100 years return period. It was also possible to identify that floods are the most important driver for the sediment transport along the estuary, while the tide effect in the morphodynamics is restricted to the downstream estuarine region. This work demonstrated the importance of the numerical modelling tools to better understand the effects of climate change at local scales through the representation of the estuarine hydrodynamic pattern evolution for future climate scenarios.This research was partially supported by the Strategic Funding UID/Multi/04423/2019 through national funds provided by FCT—Foundation for Science and Technology and European Regional Development Fund (ERDF). This contribution has also been funded by the European Union MarRISK project: Adaptación costera ante el Cambio Climático: conocer los riesgos y aumentar la resiliencia (0262_MarRISK_1_E), through the EP INTERREG V A España-Portugal (POCTEP) program. The authors want also to acknowledge the contract funds provided by the project EsCo-Ensembles (PTDC/ECI-EGC/30877/2017), co-financed by NORTE 2020, Portugal 2020 and the European Union through the ERDF, and by FCT through national funds