1,680 research outputs found

    Stated belief and play in normal form games

    Get PDF
    Using data on one-shot games, we investigate the assumption that players respond to underlying expectations about their opponent�s behavior. In our laboratory experiments, subjects play a set of 14 two-person 3x3 games, and state first order beliefs about their opponent�s behavior. The sets of responses in the two tasks are largely inconsistent. Rather, we find evidence that the subjects perceive the games differently when they (i) choose actions, and (ii) state beliefs � they appear to pay more attention to the opponent�s incentives when they state beliefs than when they play the games. On average, they fail to best respond to their own stated beliefs in almost half of the games. The inconsistency is confirmed by estimates of a unified statistical model that jointly uses the actions and the belief statements. There, we can control for noise, and formulate a statistical test that rejects consistency. Effects of the belief elicitation procedure on subsequent actions are mostly insignificant

    Beliefs and actions in the trust game: creating instrumental variables to estimate the causal effect

    Get PDF
    In many economic contexts, an elusive variable of interest is the agent's expectation about relevant events, e.g. about other agents' behavior. Recent experimental studies as well as surveys have asked participants to state their beliefs explicitly, but little is known about the causal relation between beliefs and other behavioral variables. This paper discusses the possibility of creating exogenous instrumental variables for belief statements, by shifting the probabilities of the relevant events. We conduct trust game experiments where the amount sent back by the second player (trustee) is exogenously varied by a random process, in a way that informs only the �first player (trustor) about the realized variation. The procedure allows detecting causal links from beliefs to actions under plausible assumptions. The IV estimates indicate a signi�ficant causal effect, comparable to the connection between beliefs and actions that is suggested by OLS analyses

    Histopathological and immunohistochemical study of the hepatic lesions experimentally induced by Entamoeba dispar

    Get PDF
    The sequence of hepatic necrotic-inflammatory events produced by Entamoeba dispar are originally described in this work. For the first time the experimental lesions produced by E. dispar were described in details, as well as the distribution of the trophozoites detected by the immunohistochemistry. Animals experimentally infected with E. dispar presented necrosis, thrombosis and chronic granulomatous inflammation. Immunoreactive products derived from trofozoites were observed close or associated with trophozoites, epithelioid cells, leucocytes and hepatocytes. Few are the articles on the literature about virulence of E. dispar, which is approximately 9 times more frequent than to Entamoeba histolytica (E. histolytica). Variation in the virulence is therefore expected and signalizing the need of the continuity of studies with E. dispar strains from different places in the world. Taking into account that E. dispar is a closely related species to E. histolytica, these studies could determine new elements involved with E. histolytica pathogenesis, helping us to better understand the disease

    2,6-Diphenylpyridine

    Get PDF
    In the title compound, C17H13N, the dihedral angles between the pyridine ring and the phenyl rings are 29.68 (18) and 26.58 (17)°. In the crystal structure, the mol­ecules are linked by a weak C-H inter­action, leading to [01] chains. There are no further significant inter­molecular inter­actions

    Frog: a FRee Online druG 3D conformation generator

    Get PDF
    In silico screening methods based on the 3D structures of the ligands or of the proteins have become an essential tool to facilitate the drug discovery process. To achieve such process, the 3D structures of the small chemical compounds have to be generated. In addition, for ligand-based screening computations or hierarchical structure-based screening projects involving a rigid-body docking step, it is necessary to generate multi-conformer 3D models for each input ligand to increase the efficiency of the search. However, most academic or commercial compound collections are delivered in 1D SMILES (simplified molecular input line entry system) format or in 2D SDF (structure data file), highlighting the need for free 1D/2D to 3D structure generators. Frog is an on-line service aimed at generating 3D conformations for drug-like compounds starting from their 1D or 2D descriptions. Given the atomic constitution of the molecules and connectivity information, Frog can identify the different unambiguous isomers corresponding to each compound, and generate single or multiple low-to-medium energy 3D conformations, using an assembly process that does not presently consider ring flexibility. Tests show that Frog is able to generate bioactive conformations close to those observed in crystallographic complexes. Frog can be accessed at http://bioserv.rpbs.jussieu.fr/Frog.html

    Bloch Brane

    Full text link
    We investigate a system described by two real scalar fields coupled with gravity in (4, 1) dimensions in warped spacetime involving one extra dimension. The results show that the parameter which controls the way the two scalar fields interact induces the appearence of thick brane which engenders internal structure, driving the energy density to localize inside the brane in a very specific way.Comment: 13 pages, 6 figures; some misprints corrected, to appear in JHE

    The Mythology of Game Theory

    Get PDF
    Non-cooperative game theory is at its heart a theory of cognition, specifically a theory of how decisions are made. Game theory\u27s leverage is that we can design different payoffs, settings, player arrays, action possibilities, and information structures, and that these differences lead to different strategies, outcomes, and equilibria. It is well-known that, in experimental settings, people do not adopt the predicted strategies, outcomes, and equilibria. The standard response to this mismatch of prediction and observation is to add various psychological axioms to the game-theoretic framework. Regardless of the differing specific proposals and results, game theory uniformly makes certain cognitive assumptions that seem rarely to be acknowledged, much less interrogated. Indeed, it is not widely understood that game theory is essentially a cognitive theory. Here, we interrogate those cognitive assumptions. We do more than reject specific predictions from specific games. More broadly, we reject the underlying cognitive model implicitly assumed by game theory

    Nevoid Basal-cell Syndrome: Literature Review And Case Report In A Family.

    Get PDF
    The Nevoid Basal-Cell Carcinoma Syndrome (NBCC), or as it is also referred to, basal-cell nevus syndrome or Gorlin-Goltz syndrome, is characterized by multiple early-appearing basal cell carcinomas, keratocytosis of the mandible, and anomalies of the ocular, skeletal reproductive system. We describe four patients in the same family, all of them possessing a large number of skin tumors associated with other typical clinical and X-Ray anomalies of NBCC. The definitive treatment of NBCC has yet to be established, however, early diagnosis is very important as well as the periodical follow-up examination of ten patients, mainly due to the transformations in the skin lesions that may occur.113391792

    Oxidative status imbalance in patients with metabolic syndrome: Role of the myeloperoxidase/hydrogen peroxide axis

    Get PDF
    The present study evaluated the cardiometabolic and redox balance profiles in patients with Metabolic Syndrome compared to apparently healthy individuals, and the participation of the myeloperoxidase/hydrogen peroxide axis in systemic lipid peroxidation. Twenty-four patients with Metabolic Syndrome and eighteen controls underwent a full clinical assessment. Venous blood samples were collected for general biochemical dosages, as well as for the oxidative stress analyses (superoxide dismutase, catalase, and arginase activities; and lipid peroxidation, myeloperoxidase activity, nitrite, and hydrogen peroxide concentrations in plasma). Arterial stiffness was assessed by radial artery applanation tonometry. Plasma lipid peroxidation, erythrocyte superoxide dismutase activity, myeloperoxidase activity, and hydrogen peroxide concentrations were shown to be increased in Metabolic Syndrome patients, without significant differences for the other enzymes, plasma nitrite concentrations, and arterial stiffness. Linear regression analysis revealed a positive and significant correlation between lipid peroxidation and myeloperoxidase and also between this enzyme and hydrogen peroxide. In contrast, such correlation was not observed between lipid peroxidation and hydrogen peroxide. In summary, Metabolic Syndrome patients exhibited evident systemic redox imbalance compared to controls, with the possible participation of the myeloperoxidase/hydrogen peroxide axis as a contributor in lipid peroxidation

    Programa de Enriquecimiento Instrumental (PEI) básico en niños con TDAH y Dislexia

    Get PDF
    Testes de eficácia do Programa de Enriquecimento Instrumental (PEI), versão básica, sobre inteligibilidade, processamento visoespacial e flexibilidade cognitiva. Como essas habilidades podem estar comprometidas em distúrbios neurológicos, como TDAH e dislexia, sua eficácia foi investigada em 22 crianças. Ou o grupo experimental (GE) foi comparado ou controlado por testes neuropsicológicos, com 26 sessões intervencionistas. Uma interação entre ou grupo nenhum momento e como diferenças de desempenho entre os dois nos analisaram momentos. Essa comparação revela o principal interesse das tarefas de flexibilidade cognitiva com um grande tamanho de efeito; em oito medidas com efeito moderado tamanho (incluindo medidas de inteligência,visospatial processamento e funções executivas) e em 13 medidas com tamanho de efeito pequeno. Ou grupo de controle apresentou maior ganho apenas em consulta. Conclui-se que o IPE básico mostra principalmente os efeitos da flexibilidade cognitiva em crianças com TDAH e dislexia
    corecore