Serum antioxidant parameters in patients poisoned by different xenobiotics

There is a great diversity of the acute drugs overdose cases in clinical toxicology. Clinical situation is complicated by the coexistence of factors predisposing to the development o f adverse drug reactions (chronic use of drugs, polypharmacy, alcohol or drugs dependence, nutritional disorders) and by the presence of chronic organ damage, especially the liver and the kidney. The aim of this study w as to evaluate whether there are sensitive plasma markers belonging to the antioxidant system in patients exposed to various xenobiotics. We measured the activity of antioxidant parameters: catalase (CAT), glutathione peroxidase (GPX3), glutathione (GSH), sulfhydryl groups (-SH), carbonyl groups (=CO) and free radicals (2,2-diphenyl-1-picrylhydrazyl, DPPH, assay) in serum of 49 patients with acute intoxication caused by carbamazepine (CBZ, n = 9), mixed drug intoxication (MDI) (n = 9), alcohol withdrawal syndrome (AWS, n = 9), acetaminophen (APAP, n = 7), tricyclic antidepressants (TCAs) (n = 5), valproic acids (VA, n = 4), narcotics (N, n = 3), and three others (benzodiazepines, BZD, n = 2; barbiturates, n = 1). The results were compared w ith the parameters of not intoxicated patients (n = 39). All patients had lower catalase activity in comparison to the control group (41.9 ± 16.5 vs. 196.0 ± 82.2 U/mg protein, p = 0.000), while the increase of GSH level was particularly apparent only in patients with AWS (391.3 ± 257.9 pmol/mg protein) compared to the control group (171.4 ± 88.4 pmol/mg protein, p = 0.034) and to patients intoxicated with carbamazepine (152.8 ± 102.5 pmol/mg protein, p = 0.027). Some differences, but without statistical significance, were also observed in GPX3 activity between different groups of poisoned patients

Vision System Measuring the Position of an Aircraft in Relation to the Runway during Landing Approach

This paper presents a vision system that measures the position of an aircraft relative to the runway (RWY) during a landing approach. It was assumed that all the information necessary for a correct approach was based entirely on an analysis of the image of the runway and its surroundings. It was assumed that the way the algorithm works, as well as possible, should imitate the pilot’s perception of the runway. Taking into account the above and the fact that the infrastructure at each airport is different, it has been decided to use artificial neural networks with a dedicated learning process for any airport, based on the simulation environments. Such an action will enable the generation of a synthetic video sequence without the need for costly and time-consuming flights. The presented solution was tested in real flight conditions on an experimental aircraft, and the selected test results are presented in this article

Vision System Measuring the Position of an Aircraft in Relation to the Runway during Landing Approach

This paper presents a vision system that measures the position of an aircraft relative to the runway (RWY) during a landing approach. It was assumed that all the information necessary for a correct approach was based entirely on an analysis of the image of the runway and its surroundings. It was assumed that the way the algorithm works, as well as possible, should imitate the pilot’s perception of the runway. Taking into account the above and the fact that the infrastructure at each airport is different, it has been decided to use artificial neural networks with a dedicated learning process for any airport, based on the simulation environments. Such an action will enable the generation of a synthetic video sequence without the need for costly and time-consuming flights. The presented solution was tested in real flight conditions on an experimental aircraft, and the selected test results are presented in this article

System of the supervising and controlling the technological process

W pracy zaprezentowano zaawansowany system sterowania i akwizycji danych (SCADA), umożliwiający projektantom tworzyć specjalistyczne aplikacje sterująco-monitorujące dla różnych gałęzi przemysłu. Zrealizowana aplikacja komunikuje się z urządzeniami obiektowymi, takimi jak sterowniki PLC, instrumenty pomiarowe w czasie rzeczywistym. Ponieważ wszystkie dane są monitorowane i zapisywane, system szybko reaguje na zaistniałe sytuacje zgodnie z zaprogramowaną procedurą i żądaniami operatoraThis paper presents an advanced control and data acquisition (SCADA) system that allows designers to create specialized applications to control and monitoring for a different of industries. Completed application communicates with field devices such as PLCs, measuring instruments in real time. Since all data is monitored and recorded, the system responds quickly to opportunities in accordance with the programmed procedure and requests the operator