Sistema inteligente para el tratamiento de ruidos

El principal objetivo es lograr recuperar sonidos similares automáticamente de una base de datos con sonidos previamente almacenados. Se utiliza un sonido como argumento de la consulta y se obtienen los resultados con un grado de confiabilidad parametrizable. Este estudio se desarrolla en el marco de las investigaciones realizadas en el laboratorio AIGroup, bajo el nombre de proyecto FIC. En la propuesta del sistema se incluye la capacidad de distinción de ruidos, música, voz y combinación de los anteriores.Eje: Agentes y Sistemas InteligentesRed de Universidades con Carreras en Informática (RedUNCI

Sistema inteligente para el tratamiento de ruidos

El principal objetivo es lograr recuperar sonidos similares automáticamente de una base de datos con sonidos previamente almacenados. Se utiliza un sonido como argumento de la consulta y se obtienen los resultados con un grado de confiabilidad parametrizable. Este estudio se desarrolla en el marco de las investigaciones realizadas en el laboratorio AIGroup, bajo el nombre de proyecto FIC. En la propuesta del sistema se incluye la capacidad de distinción de ruidos, música, voz y combinación de los anteriores.Eje: Agentes y Sistemas InteligentesRed de Universidades con Carreras en Informática (RedUNCI

Paul Ricoeur in dialogo

Numerosi studiosi dell'area europea si incontrano per mettersi idealmente "in dialogo" con il Maestro Paul Ricoeur su argomenti particolarmente pregnanti del nostro tempo, concernenti l'etica dei rapporti interpersonali all'interno delle società complesse; la giustizia e la discussione attorno ai suoi fondamenti e alle sue procedure; la convinzione delle scelte religiose che si incontrano nei contesti multiculturali odierni. Ogni parte del testo inizia con un saggio di Paul Ricoeu

Response of ferrite, bainite, martensite, and retained austenite to a fire cycle in a fire-resistant steel

Understanding the kinetics of microstructural degradation during the event of a fire is of major relevance to future optimization of fire-resistant steels (FRS). In this work, we use in situ synchrotron X-ray diffraction to assess the rapid thermally-assisted degradation of different starting microstructures, such as (i) ferrite + pearlite; (ii) bainite + retained austenite, and (iii) martensite + retained austenite, during the simulation of a fire cycle in a Fe-0.13C-0.11Cr-0.38Mo-0.04V FRS. Our results show that retained austenite is the most unstable phase, especially when generated by faster cooling rates, decomposing at temperatures as low as 180 °C during fire simulations. Bainite and martensite are both unstable and undergo recovery and carbon desaturation via secondary precipitation of cementite. However, bainite is comparatively more stable than martensite since its decomposition starts at 400 °C, while for martensite it occurs at 320 °C. We also present a methodology to deconvolute the effect of temperature on the increased background and signal intensities of the X-ray spectra, allowing the direct observation of the kinetics of secondary cementite precipitation

Collagen V α1 Chain Decrease in Papillary Dermis from Early Systemic Sclerosis: A New Proposal in Cutaneous Fibrosis Molecular Structure

Cutaneous fibrosis is one of the main features of systemic sclerosis (SSc). Recent findings correlated abnormal collagen V (Col V) deposition in dermis with skin thickening and disease activity in SSc. Considering that Col V is an important regulator of collagen fibrillogenesis, understanding the role of Col V in the first two years of the skin fibrosis in SSc (early SSc) can help to determine new targets for future treatments. In this study, we analyzed the morphological, ultrastructural and molecular features of α1(V) and α2(V) chains and the expression of their coding genes COL5A1 and COL5A2 in collagen fibrillogenesis in early-SSc. Skin biopsies were obtained from seven consecutive treatment-naïve patients with SSc-related fibrosis and four healthy controls. Our data showed increased α1(V) and α2(V) chain expression in the reticular dermis of early-SSc patients; however, immunofluorescence and ultrastructural immunogold staining determined a significant decreased expression of the α1(V) chain along the dermoepidermal junction in the papillary dermis from early-SSc-patients in relation to the control (12.77 ± 1.34 vs. 66.84 ± 3.36; p < 0.0001). The immunoblot confirmed the decreased expression of the α1(V) chain by the cutaneous fibroblasts of early-SSc, despite the increased COL5A1 and COL5A2 gene expression. In contrast, the α2(V) chain was overexpressed in the small vessels (63.18 ± 3.56 vs. 12.16 ± 0.81; p < 0.0001) and capillaries (60.88 ± 5.82 vs. 15.11 ± 3.80; p < 0.0001) in the reticular dermis of early-SSc patients. Furthermore, COLVA2 siRNA in SSc cutaneous fibroblasts resulted in a decreased α1(V) chain expression. These results highlight an intense decrease in the α1(V) chain along the dermoepidermal junction, suggesting an altered molecular histoarchitecture in the SSc papillary dermis, with a possible decrease in the expression of the α1(V)3 homotrimeric isoform, which could interfere with the thickening and cutaneous fibrosis related to SSc