Advancing Intra-operative Precision: Dynamic Data-Driven Non-Rigid Registration for Enhanced Brain Tumor Resection in Image-Guided Neurosurgery

During neurosurgery, medical images of the brain are used to locate tumors and critical structures, but brain tissue shifts make pre-operative images unreliable for accurate removal of tumors. Intra-operative imaging can track these deformations but is not a substitute for pre-operative data. To address this, we use Dynamic Data-Driven Non-Rigid Registration (NRR), a complex and time-consuming image processing operation that adjusts the pre-operative image data to account for intra-operative brain shift. Our review explores a specific NRR method for registering brain MRI during image-guided neurosurgery and examines various strategies for improving the accuracy and speed of the NRR method. We demonstrate that our implementation enables NRR results to be delivered within clinical time constraints while leveraging Distributed Computing and Machine Learning to enhance registration accuracy by identifying optimal parameters for the NRR method. Additionally, we highlight challenges associated with its use in the operating room

AES 2011 Abstract Title: Temporal theta oscillation enhancement predicts successful memory encoding

Abstract Rationale Theta oscillations The amplitude of these oscillations was correlated to successful memory retrieval in a verbal memory task Methods Epileptic patients implanted with subdural electrodes for seizure localization were tested on two tasks. The first one was a classic multi-item short-term memory task The subjects had to indicate using a key press whether the test image was part of the previous image series or not. In the second task, the subjects were shown a series of 4-6 images. After a short delay, the patients were instructed to arrange the previously presented objects in the order in which they appeare

AES 2011 Abstract Title: Temporal theta oscillation enhancement predicts successful memory encoding

Abstract Rationale Theta oscillations The amplitude of these oscillations was correlated to successful memory retrieval in a verbal memory task Methods Epileptic patients implanted with subdural electrodes for seizure localization were tested on two tasks. The first one was a classic multi-item short-term memory task The subjects had to indicate using a key press whether the test image was part of the previous image series or not. In the second task, the subjects were shown a series of 4-6 images. After a short delay, the patients were instructed to arrange the previously presented objects in the order in which they appeare