Bats that walk: a new evolutionary hypothesis for the terrestrial behaviour of New Zealand's endemic mystacinids.

RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.BACKGROUND: New Zealand's lesser short-tailed bat Mystacina tuberculata is one of only two of c.1100 extant bat species to use a true walking gait when manoeuvring on the ground (the other being the American common vampire bat Desmodus rotundus). Mystacina tuberculata is also the last surviving member of Mystacinidae, the only mammalian family endemic to New Zealand (NZ) and a member of the Gondwanan bat superfamily Noctilionoidea. The capacity for true quadrupedal terrestrial locomotion in Mystacina is a secondarily derived condition, reflected in numerous skeletal and muscular specializations absent in other extant bats. The lack of ground-based predatory native NZ mammals has been assumed to have facilitated the evolution of terrestrial locomotion and the unique burrowing behaviour of Mystacina, just as flightlessness has arisen independently many times in island birds. New postcranial remains of an early Miocene mystacinid from continental Australia, Icarops aenae, offer an opportunity to test this hypothesis. RESULTS: Several distinctive derived features of the distal humerus are shared by the extant Mystacina tuberculata and the early Miocene Australian mystacinid Icarops aenae. Study of the myology of M. tuberculata indicates that these features are functionally correlated with terrestrial locomotion in this bat. Their presence in I. aenae suggests that this extinct mystacinid was also adapted for terrestrial locomotion, despite the existence of numerous ground-based mammalian predators in Australia during the early Miocene. Thus, it appears that mystacinids were already terrestrially-adapted prior to their isolation in NZ. In combination with recent molecular divergence dates, the new postcranial material of I. aenae constrains the timing of the evolution of terrestrial locomotion in mystacinids to between 51 and 26 million years ago (Ma). CONCLUSION: Contrary to existing hypotheses, our data suggest that bats are not overwhelmingly absent from the ground because of competition from, or predation by, other mammals. Rather, selective advantage appears to be the primary evolutionary driving force behind habitual terrestriality in the rare bats that walk. Unlike for birds, there is currently no evidence that any bat has evolved a reduced capacity for flight as a result of isolation on islands

The effect of nasal steroid aqueous spray on nasal complaint scores and cellular infiltrates in the nasal mucosa of patients with nonallergic, noninfectious perennial rhinitis

Topical corticosteroids are the therapy of choice for nonallergic, noninfectious perennial rhinitis (NANIPER). However, the efficacy of steroid therapy in NANIPER is controversial, as is its mode of action. To our surprise, of 300 patients initially diagnosed as having NANIPER, only 65 reached threshold nasal symptom scores. Patients were randomized into four different treatment regimens: placebo administered twice daily (BD) for 8 weeks, fluticasone propionate aqueous nasal spray (FPANS) (200 microg) once daily (OD) and placebo OD for 8 weeks, FPANS (200 microg) OD and placebo OD for 4 weeks followed by FPANS (200 microg) BD for 4 weeks, and FPANS (200 microg) BD for 8 weeks. A small decrease in nasal symptoms was found, which only reached significance for sneezing in the FPANS 200 microg BD group. A significant dose-dependent decrease in immunocompetent cells was found in nasal biopsy specimens obtained before, after 4 weeks, and after 8 weeks of treatment. We conclude that FPANS did not significantly reduce nasal symptoms in this group of selected NANIPER patients, even though a significant effect on cells in the nasal mucosa was see

Mast cells, eosinophils and IgE-positive cells in the nasal mucose of patients with vasomotor rhinitis - An immunohistochemical study

Vasomotor rhinitis (VMR) is a disorder of unknown pathogenesis. Forty patients with VMR were carefully selected on the basis of inclusion and exclusion criteria proposed by Mygind and Weeke. Nasal biopsy specimens were taken in the patient group as well as in a group of ten controls. Brush cytology was also taken in the VMR group. Inflammatory cells were identified and counted in the nasal mucosa, with the use of immunohistochemical techniques and a panel of monoclonal antibodies. Eosinophils were studied with the use of BMK13, EG2, and Giemsa. Mast cells were studied with anti-chymase (B7), anti-tryptase (G3) and toluidine blue. Sections were stained with IgE as well. There was no significant difference in the number of eosinophils, mast cells and IgE-positive cells between the two groups. Additionally, in contrast with other reports, in sections that were double-stained with anti-chymase and anti-tryptase, single chymase-positive cells were found

Australia's Oldest Marsupial Fossils and their Biogeographical Implications

Background: We describe new cranial and post-cranial marsupial fossils from the early Eocene Tingamarra Local Fauna in Australia and refer them to Djarthia murgonensis, which was previously known only from fragmentary dental remains. Methodology/Principal Findings: The new material indicates that Djarthia is a member of Australidelphia, a pan-Gondwanan clade comprising all extant Australian marsupials together with the South American microbiotheres. Djarthia is therefore the oldest known crown-group marsupial anywhere in the world that is represented by dental, cranial and postcranial remains, and the oldest known Australian marsupial by 30 million years. It is also the most plesiomorphic known australidelphian, and phylogenetic analyses place it outside all other Australian marsupials. Conclusions/Significance: As the most plesiomorphic and oldest unequivocal australidelphian, Djarthia may approximate the ancestral morphotype of the Australian marsupial radiation and suggests that the South American microbiotheres may be the result of back-dispersal from eastern Gondwana, which is the reverse of prevailing hypotheses

Two new species of fossil Leggadina (Rodentia: Muridae) from Northwestern Queensland

Only three species of fossil murine have been described to date in Australia even though they are often found in fossil deposits and can be highly useful in understanding environmental change over time. Until now the genus Leggadina, a group of short-tailed mice that is particularly well adapted to an arid environment, was only known from two extant species: L. forresti and L. lakedownensis. Here two new fossil species of the genus are described from sites in northwestern Queensland. Leggadina gregoriensis sp. nov. comes from the Early Pleistocene Rackham’s Roost Site in the Riversleigh World Heritage Area and Leggadina macrodonta sp. nov. is from the Plio-Pleistocene Site 5C at Floraville Station. The evolution of the genus Leggadina and the lineage’s response to palaeoecological factors is considered. Taphonomy of the two fossil deposits is examined and shows marked differences in both faunal composition of the assemblages and preservation. Description of L. gregoriensis and L. macrodonta extends the known temporal range of the Leggadina lineage by over 2 million years

First Eocene bat from Australia

Remains of a bat, Australonycteris clarkae, gen. et sp. nov., are reported from freshwater clays radiometrically dated at 54.6 million years old in southeastern Queensland, Australia. It is the oldest bat yet recorded for the Southern Hemisphere and one of the world\u27s oldest. Previously, the earliest records for bats came from the Northern Hemisphere and were of Sparnacian age in Europe, Wasatchian in North America, and late early Eocene in North Africa. The North American Wyonycteris chalix, originally described as a latest Paleocene bat and as such the world\u27s oldest, is re-examined. Its lack of key bat synapomorphies and overall morphology do not support the claim that it is a bat. Early bats probably entered Australia via Asia rather than South America, although their appearance in Australia predates the final breakup of Gondwana. The Australian fossils described here (a lower molar, upper premolar, edentulous dentary fragment, and part of a periotic) may corroborate the hypothesis that modern bat groups evolved from isolated immigrant archaic bats somewhere in the Southern Hemisphere in the early Eocene

Miocene possums

15 p. : ill. ; 26 cm.Includes bibliographical references (p. 13-15).The first unique genus of ringtail possums from the Riversleigh World Heritage Area in Australia is diagnosed and described. Gawinga aranaea is the type and only species of the new genus and is known from nine isolated lower molars. It has been recovered from three Riversleigh deposits: two are of early to mid-Miocene age, while the age of the other has yet to be determined. The new possum is larger than Oligo-Miocene species of Paljara, Pildra, and Marlu, but smaller than most extant taxa. It is characterised by a distinctive lower molar cusp morphology of parallel ridges extending primarily from the cristid obliqua, filling the occlusal basins. Additional autapomorphies include: extended, shelflike protostylid cristids and a bisected posthypocristid on m1, and posterior molars that have a metaconid ridge posterobuccal to the metaconid and an anteriorly positioned protoconid relative to the metaconid. It also possesses an enlarged protostylid on m1, a feature otherwise known only in extant genera. The precise phylogenetic position of Gawinga within the pseudocheirid radiation has yet to be determined, but it is tentatively identified here to be a highly derived pseudocheirid, apomorphic with respect to Paljara and Pildra species, and with no known descendants

Gawinga ROBERTS & ARCHER & HAND & GODTHELP 2007, new genus

Gawinga, new genus TYPE SPECIES: Gawinga aranaea n.sp. DIAGNOSIS: As for the type species until additional species are known. ETYMOLOGY: Gawinga is a word meaning ‘‘possum’’, as spoken by the late Ivy George of Riversleigh Station, northwestern Queensland. Gender is considered to be feminine. DISTRIBUTION AND AGE: As for the type species.Published as part of ROBERTS, KAREN K., ARCHER, MICHAEL, HAND, SUZANNE J. & GODTHELP, HENK, 2007, New Genus and Species of Extinct Miocene Ringtail Possums (Marsupialia: Pseudocheiridae), pp. 1-16 in American Museum Novitates 3560 (1) on page 2, DOI: 10.1206/0003-0082(2007)3560[1:NGASOE]2.0.CO;2, http://zenodo.org/record/538746