1,104 research outputs found

    Inter-rater reliability of the hand activity level using cyclic and non-cyclic tasks

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    2010 Spring.Includes bibliographic references (pages 49-53).Research has shown a link between exposure to excessive repetitive motion and the development of musculoskeletal disorders. Exposure assessment tools have been developed to measure risk factors, such as repetitive motion, and their relationship to health outcomes. To accurately evaluate risk factors, a tool must be both valid and reliable. The present study evaluated the inter-rater reliability of the Hand Activity Level (HAL), which is one portion of the ACGIH TLV for hand activity. Workers from a large appliance manufacturing facility were video recorded and assessed on a HAL rating scale by two independent raters. The HAL was originally designed to be used for tasks cyclic in nature, however, in the present study non-cyclic tasks were also rated. Work task HAL ratings were compared across raters using a weighted Pearson Product Moment Correlation Coefficient. Fair to moderate inter-rater reliability was found for both cyclic and non-cyclic tasks. A paired t-test was used to determine if there was a significant difference in correlation coefficients between HAL ratings for cyclic and noncyclic tasks. No significant difference was found between the correlation coefficients of cyclic and non-cyclic tasks. The present study found that the HAL is a reliable measure for both cyclic and non-cyclic tasks. Additional studies should be conducted to determine if the HAL is a valid measure of repetition in non-cyclic tasks

    Best Practices in Educator Preparation

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    One of the themes emphasized in the College of Education (COE) Conceptual Framework is excellence in teaching. As defined in the Conceptual Framework, excellence in teaching embodies the use of best practices which embody a variety of educational ideas and activities that lead to improved student learning. The phrase “best practice” is used frequently in fields such as medicine or law to describe reputable work based on current research and employing the latest knowledge, technology, and procedures in the field (Zemelman, Daniels, & Hyde, 1998). However, best practice in education has been somewhat difficult to define

    Mindful Artmaking in Elementary Classrooms: A Path to Emotional Regulation

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    Abstract In an era dominated by technological advancements and mounting external pressures, the emotional and mental well-being of the younger generation is a growing concern. This research paper explores the intricate relationship between mindfulness, art-making, and emotional regulation within the context of elementary classrooms. The modern world, filled with a plethora of stimuli, has escalated stress levels among individuals, especially children, leading to a surge in mental health issues. Mindfulness, deeply rooted in ancient traditions, teaches individuals to stay present, fostering a non-judgmental awareness of their thoughts and emotions. Art-making, on the other hand, serves as a medium for emotional expression and self-discovery, providing a platform for individuals to externalize and process their feelings creatively. When combined, these tools form a potent strategy to help children understand, express, and regulate their emotions. This study delves into the foundational theories of mindfulness, art-making, and emotional regulation, investigating their relevance and applicability in today\u27s educational settings. Furthermore, the paper underscores the symbiotic relationship between these themes, emphasizing their collective role in fostering emotional balance and mental well-being. As the complexities of the modern world continue to unfold, embracing the therapeutic potential of mindful art-making becomes imperative for cultivating resilience and emotional stability among the younger generation

    Language Learners, Inequality Regimes, and Secondary Schooling: Dilemmas of the New South

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    This paper explores the structure of the secondary education system in Northwest Arkansas and how it shapes the culture of education for newly arrived Latino immigrants. Significant achievement gaps remain between non-Hispanic white students and Latinos within secondary education. Uncovering possible causes for this gap is necessary in order to allow equal educational opportunity for all students. While prior researchers debate the method of language instruction as a barrier to education, there has been little attention to the relationship between organizational structure and levels of achievement. In-depth interviews with teachers and administrators reveal a consistent theme: large amounts of time and energy spent focused on accountability measures seem to privilege the middle-class, native-English speaking student. I find that attempts at English education for a large influx of non-English speakers constructs secondary education as a type of inequality regime by creating and maintaining a class- and race-based concept of the `ideal student.\u27 Latino students, in particular, struggle to attain the ideal student status

    Space-Time Forecasting Using Soft Geostatistics: A Case Study in Forecasting Municipal Water Demand for Phoenix, AZ

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    Managing environmental and social systems in the face of uncertainty requires the best possible forecasts of future conditions. We use space-time variability in historical data and projections of future population density to improve forecasting of residential water demand in the City of Phoenix, Arizona. Our future water estimates are derived using the first and second order statistical moments between a dependent variable, water use, and an independent variable, population density. The independent variable is projected at future points, and remains uncertain. We use adjusted statistical moments that cover projection errors in the independent variable, and propose a methodology to generate information-rich future estimates. These updated estimates are processed in Bayesian Maximum Entropy (BME), which produces maps of estimated water use to the year 2030. Integrating the uncertain estimates into the space-time forecasting process improves forecasting accuracy up to 43.9% over other space-time mapping methods that do not assimilate the uncertain estimates. Further validation studies reveal that BME is more accurate than co-kriging that integrates the error-free independent variable, but shows similar accuracy to kriging with measurement error that processes the uncertain estimates. Our proposed forecasting method benefits from the uncertain estimates of the future, provides up-to-date forecasts of water use, and can be adapted to other socioeconomic and environmental applications.

    Integration Of Fermentation And Organic Synthesis: Studies Of Roquefortine C And Biosynthetic Derivatives

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    Roquefortine C is one of the most ubiquitous indoline alkaloids of fungal origin. It has been isolated from over 30 different species of Penicillium fungi and has garnered attention in recent years for its role as a biosynthetic precursor to the triazaspirocyclic natural products glandicoline B, meleagrin, and oxaline. The triazaspirocyclic motif, which encompasses three nitrogen atoms attached to one quaternary carbon forming a spirocyclic scaffold, is a unique chemical moiety that has been shown to impart a wide array of biological activity, from anti-bacterial activity and antiproliferative activity against cancer cell lines to anti-biofouling against marine organisms. Despite the promise of these compounds in the pharmaceutical and materials industries, few syntheses of triazaspirocycles exist in the literature. The biosynthesis of roquefortine C-derived triazaspirocycles, however, provides inspiration for the synthesis of these compounds, namely through a nitrone-promoted transannular rearrangement. This type of internal rearrangement has never been carried out synthetically and would provide an efficient stereoselective synthesis of triazaspirocycles. This work encompasses efforts towards elucidating the biosynthetic pathway of roquefortine C-derived triazaspirocycles as well as synthetic efforts towards the construction of triazaspirocycles. Chapter 1 will discuss a large-scale fermentation procedure for the production of roquefortine C from Penicillium crustosum. Chapters 2 and 3 explore (through enzymatic and synthetic means, respectively) the formation of the key indoline nitrone moiety required for the proposed transannular rearrangement. Finally, chapter 4 will discuss synthetic efforts towards the synthesis of triazaspirocycles. This work has considerably enhanced our understanding of the roquefortine C biosynthetic pathway and the unique chemistry of this natural product, and our efforts towards the synthesis of triazaspirocycles will facilitate the use of these compounds in numerous applications

    Holistic Christian formation for enduring leadership

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    https://place.asburyseminary.edu/ecommonsatsdissertations/1364/thumbnail.jp

    The American novelist interprets the student of higher education /

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    Gober\u27s Georgia form book and procedure, a collection of legal forms with annotations from the reports of the Supreme Court and the Court of Appeals of Georgia on questions relating to forms and procedure; prepared for the use of the judiciary, the bar, the officers of court, and business me

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    Excerpt from the preface: The work of preparing this volume has developed out of all proportion to what I anticipated in the outset. The great trouble under our system is that there are so many things that are not fixed and determined. Our system of pleading provides that a party must plainly, fully and distinctly set forth his cause of action, and this leaves the form to be passed upon under the discretion of about one hundred trial judges in the City and Superior Courts, and this discretion, in many instances, is controlled by individual and particular ideas. For this reason, a form must be broad, since a precise and exact form needs its author to defend it when it is passed upon under such discretion. For this reason, it has been thought a better plan to present as much as possible forms that have been used, and to a certain extent have met with the approval of the profession, rather than to present radical changes. Geo, E. Gobee. Atlanta, Ga., April 17, 1917.https://digitalcommons.law.uga.edu/historic_treat/1007/thumbnail.jp

    GENE EXPRESSION PROFILES REVEAL ALTERNATIVE TARGETS OF THERAPEUTIC INTERVENTION FOR THE TREATMENT OF DRUG-RESISTANT NON-SMALL CELL LUNG CANCERS

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    More than 80% of lung cancer patients die from drug-resistant, metastatic disease. Our focus is to identify new drug targets and alternative therapeutic strategies to improve outcomes for this majority of lung cancer patients. We aimed to satisfy the need for new treatment approaches by leveraging the information gained from the development of two multigene biomarker predictors of Epidermal Growth Factor Receptor Inhibitors (EGFRI) response in Non-Small Cell Lung Cancer (NSCLC). From these data, we first identified TGFβ signaling as a possible modulator of EGFRI resistance and I hypothesized that TGFβ signaling participates in the development and maintenance of erlotinib-resistance and -sensitivity and regulates the gene expression of the miRNA comprising the signature of response. To identify novel putative treatment strategies for overcoming EGFRI resistance, we leveraged the raw data used to build the EGFRI-response predictors of NSCLC cells with divergent EGFRI responses using mathematical and protein-protein interaction modeling to identify a network of deregulated proteins in EGFRI-resistant cells. From this analysis, we identified a drug combination that is kills EGFRI-resistant NSCLC cells and further study will confirm if this novel strategy translates into a clinically utilizable option for the treatment of EGFRI-resistant NSCLC
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