8,290 research outputs found
Recommended from our members
Job Performance Comparisons - Mexican-American and Anglo Employees
A comparison of job performance of Mexican-American and non-Mexican-American employees in various city departments and in a large department store measured absentee rates, accident rates, efficiency ratings, promotional test scores, and sales records. The conclusions revealed that Mexican-Americans meet the same qualifications as non-Mexican-Americans in employment areas.Sociolog
Modified Gravity: living without Birkhoff I. DGP
We consider the consequences of the absence of Birkhoff's theorem in theories
of modified gravity. As an example, we calculate the gravitational force on a
test particle due to a spherical mass shell in the Dvali-Gabadaze-Porrati model
(DGP). We show that unlike in General Relativity, the force depends on the mass
distribution. In particular, the gravitational force within a spherical mass
shell depends on the geometric structure of the bulk, and is likely non-zero.Comment: 5 pages, 3 figure
Recommended from our members
Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates.
Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery and produce a limited region of therapeutic effect. In this study, we introduce a novel mode of ocular gene delivery in rhesus macaques using transscleral microneedles to inject AAV8 into the subretinal or suprachoroidal space, a potential space between the choroid and scleral wall of the eye. Using in vivo imaging, we found that suprachoroidal AAV8 produces diffuse, peripheral expression in retinal pigment epithelial (RPE) cells, but it elicited local infiltration of inflammatory cells. Transscleral subretinal injection of AAV8 using microneedles leads to focal gene expression with transduction of RPE and photoreceptors, and minimal intraocular inflammation. In comparison, intravitreal AAV8 shows minimal transduction of retinal cells, but elicits greater systemic humoral immune responses. Our study introduces a novel mode of transscleral viral delivery that can be performed without vitreoretinal surgery, with focal or diffuse transgene expression patterns suitable for different applications. The decoupling of local and systemic immune responses reveals important insights into the immunological consequences of AAV delivery to different ocular compartments surrounding the blood-retinal barrier
Health and family planning
노트 : Evaluation period: 1 Jul 1973-30 Jun 197
L'CO/LFIR Relations with CO Rotational Ladders of Galaxies Across the Herschel SPIRE Archive
We present a catalog of all CO (J=4-3 through J=13-12)), [CI], [NII] lines
available from extragalactic spectra from the Herschel SPIRE Fourier Transform
Spectrometer (FTS) archive combined with observations of the low-J CO lines
from the literature and from the Arizona Radio Observatory. This work examines
the relationships between LFIR, L'CO, and LCO/LCO(1-0). We also present a new
method for estimating probability distribution functions (PDFs) from marginal
signal-to-noise ratio Herschel} FTS spectra, which takes into account the
instrumental "ringing" and the resulting highly correlated nature of the
spectra. The slopes of log(LFIR) vs. log(L'CO) are linear for all mid- to
high-J CO lines and slightly sublinear if restricted to (U)LIRGs. The mid- to
high-J CO luminosity relative to CO J=1-0 increases with increasing LFIR,
indicating higher excitement of the molecular gas, though these ratios do not
exceed ~ 180. For a given bin in LFIR, the luminosities relative to CO J=1-0
remain relatively flat from J=6-5 through J=13-12, across three orders of
magnitude of LFIR. A single component theoretical photon-dominated region (PDR)
model cannot match these flat SLED shapes, though combinations of PDR models
with mechanical heating added qualitatively match the shapes, indicating the
need for further comprehensive modeling of the excitation processes of warm
molecular gas in nearby galaxies.Comment: 17 pages, 4 figures (including appendix), accepted by ApJ. Full
tables will be in VizieR upon publication, email first author for tables in
the meantim
Laser Vision: Lidar as a Transformative Tool to Advance Critical Zone Science
Observation and quantification of the Earth’s surface is undergoing a revolutionary change due to the increased spatial resolution and extent afforded by light detection and ranging (lidar) technology. As a consequence, lidar-derived information has led to fundamental discoveries within the individual disciplines of geomorphology, hydrology, and ecology. These disciplines form the cornerstones of critical zone (CZ) science, where researchers study how interactions among the geosphere, hydrosphere, and biosphere shape and maintain the “zone of life”, which extends from the top of unweathered bedrock to the top of the vegetation canopy. Fundamental to CZ science is the development of transdisciplinary theories and tools that transcend disciplines and inform other’s work, capture new levels of complexity,
and create new intellectual outcomes and spaces. Researchers are just beginning to use lidar data sets to answer synergistic, transdisciplinary questions in CZ science, such as how CZ processes co-evolve over long timescales and interact over shorter timescales to create thresholds, shifts in states and fluxes of water, energy, and carbon. The objective of this review is to elucidate the transformative potential of lidar for CZ science to simultaneously allow for quantification of topographic, vegetative, and hydrological processes. A review of 147 peer-reviewed lidar studies highlights a lack of lidar applications for CZ studies as 38% of the studies were focused in geomorphology, 18% in hydrology, 32% in ecology, and the remaining 12% had an interdisciplinary focus. A handful of exemplar transdisciplinary studies demonstrate
lidar data sets that are well-integrated with other observations can lead to fundamental advances in CZ science, such as identification of feedbacks between hydrological and ecological processes over hillslope scales and the synergistic co-evolution of landscape-scale CZ structure due to interactions amongst carbon, energy, and water cycles. We propose that using lidar to its full potential will require numerous advances, including new and more powerful open-source processing tools, exploiting new lidar acquisition technologies, and improved integration with physically based models and complementary in situ and remote-sensing observations. We provide a 5-year vision that advocates for the expanded use of lidar data sets and highlights subsequent potential to advance the state of CZ science
- …