RELATIONSHIP BETWEEN FORMATION OF THE FEMORAL BICONDYLAR ANGLE AND TROCHLEAR SHAPE. INDEPENDENCE OF DIAPHYSEAL AND EPIPHYSEAL GROWTH

During hominin evolution, an increase in the femoral bicondylar angle was the initial change that led to selection for protuberance of the lateral trochlear lip and elliptical profile of the lateral condyle. No correlation is found during ontogeny between the degree of femoral obliquity and of the prominence of the lateral trochlear lip. Might there be then a relationship with the elliptical profile of the lateral condyle ? On intact femoral diaphyses of juvenile humans and great apes, we compared the anteroposterior length of the lateral and medial sides of the distal metaphysis. The two diaphyseal pillars remain equal during postnatal growth in great apes, while the growth of the lateral pillar far exceeds that of the medial pillar in humans. Increase in bicondylar angle is correlated with disproportionate anteroposterior lengthening of the lateral pillar. The increased anteroposterior length of the lateral side of the metaphysis would contribute to increasing the radius of curvature of the lateral condyle, but not to projection of the lateral trochlear lip. The similar neonatal and adult femoro-patellar joint shape in humans prompted an assessment of the similarity during growth of the entire neonatal and adult epiphyses. We showed that the entire epiphysis undergoes drastic changes in proportions during postnatal growth. Finally, we emphasize the need to distinguish the cartilaginous phenotype and the ossified phenotype of the distal femoral epiphysis -and of any epiphysis- during postnatal growth. This crucial distinction applies to most postcranial bones for they almost all develop following the process of endochondral ossification

Talus et murs de soutènement dans l'Oligocène du bassin de Marseille

Glard Y., Colas G. Talus et murs de soutènement dans l'Oligocène du bassin de Marseille. In: Géologie Méditerranéenne. Tome 4, numéro 1, 1977. p. 67

Talus et murs de soutènement dans l'Oligocène du bassin de Marseille

Glard Y., Colas G. Talus et murs de soutènement dans l'Oligocène du bassin de Marseille. In: Géologie Méditerranéenne. Tome 4, numéro 1, 1977. p. 67

Analyse tridimensionnelle de l'équilibre du rachis dans la maladie de Marfan

AIX-MARSEILLE2-BU Méd/Odontol. (130552103) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Osteochondral alteration in a child treated with levetiracetam

International audienceLevetiracetam is a relatively novel antiepileptic drug used for the treatment of partial and generalized seizures in adult and children. Several animal studies describe a possible drug adverse effect on skeletal growth and metabolism. We present a case report of a 10-year-old female child who underwent a prolonged 7-year treatment with levetiracetam for sporadic secondary convulsions secondary to enterovirus encephalitis at the age of 15 months. This patient developed an osteochondritis dissecans lesion (OCD) of the talar head well treated conservatively. Only a few cases have been described of this rare type of OCD. We hypothesize a possible association between levetiracetam therapy and OCD development, suggesting the importance of long-term control of bone growth in levetiracetam-treated pediatric populations

Osteochondrosis of the medial malleolar epiphysis: A case report and review of the literature

International audienceOsteochondrosis is characterized by a disturbance of enchondral ossification in skeletally immature patients and should be investigated in children having a history of persistent foot and ankle pain. Involvement of the medial malleolar epiphysis is rarely reported