Additional file 1: of Single leg squat performance in physically and non-physically active individuals: a cross-sectional study

Supplementary material –S1. Clinical rating performances between physically active and non- physically active groups. (DOCX 14 kb

Effect of muscular exercise on endurance.

<p>Effect of muscular exercise on endurance.</p

Modification of serum bone markers activity over the race.

<p>The Figure shows the trends of serum BAP (panel A) and serum TRAP5b (panel B) over the stage race. ** indicates a significant variation (p<0.01).</p

Overall effect of muscular exercise on strength as MVIC.

<p>Overall effect of muscular exercise on strength as MVIC.</p

Modification of adipokines levels over the race.

<p>The Figure shows the trends of serum adiponectin (panel A) and serum leptin (panel B) over the stage race. ***, ** and * indicate significant variations (p<0.001, p<0.01 and p<0.05, respectively).</p

Risk of bias table.

<p>Legend: Red (-) = high risk of bias; Yellow (?) =  unknown risk of bias; Green (+) =  low risk of bias.</p

Modification of plasma osteocalcin levels and relative concentration of Glu-OC over the race.

<p>The Figure shows the trends of plasma total OC (panel A), plasma Glu-OC (panel B) and relative percentage concentration of Glu-OC (panel C) over the stage race. ** and * indicate significant variations (p<0.01 and p<0.05, respectively).</p

Modification of cortisol and testosterone concentrations over the race.

<p>The Figure shows the trends of serum cortisol (panel A) and serum testosterone (panel B) over the stage race. ** indicates a significant variation (p<0.01).</p

Literature flowchart.

<p>Literature flowchart.</p

Characteristics of the route.

<p>In the Table are reported the correspondence between day, length (km), level difference (m) of each stage along with the kind of stage and the blood sampling performed for this study and the blood sampling for official anti-doping testing.</p