Hierarchical TiN-Supported TsFDH Nanobiocatalyst for CO2 Reduction to Formate

The electrochemical reduction of CO2 to value-added products like formate represents a promising technology for the valorization of carbon dioxide. We propose a proof-of-concept bioelectrochemical system (BES) for the reduction of CO2 to formate. For the first time, our device employs a nanostructured titanium nitride (TiN) support for the immobilization of a formate dehydrogenase (FDH) enzyme. The hierarchical TiN nanostructured support exhibits high surface area and wide pore size distribution, achieving high catalytic loading, and is characterized by higher conductivity than other oxide-based supports employed for FDHs immobilization. We select the oxygen-tolerant FDH from Thiobacillus sp. KNK65MA (TsFDH) as enzymatic catalyst, which selectively reduces CO2 to formate. We identify an optimal TiN morphology for the enzyme immobilisation through enzymatic assay, reaching a catalyst loading of 59 mu g cm(-2) of specifically-adsorbed TsFDH and achieving a complete saturation of the anchoring sites available on the surface. We evaluate the electrochemical CO2 reduction performance of the TiN/TsFDH system, achieving a remarkable HCOO- Faradaic efficiency up to 76 %, a maximum formate yield of 44.1 mu mol mg(FDH)(-1) h(-1) and high stability. Our results show the technological feasibility of BES devices employing novel, nanostructured TiN-based supports, representing an important step in the optimization of these devices

Hierarchical TiN-Supported TsFDH Nanobiocatalyst for CO2 Reduction to Formate

The electrochemical reduction of CO2 to value-added products like formate represents a promising technology for the valorization of carbon dioxide. We propose a proof-of-concept bioelectrochemical system (BES) for the reduction of CO2 to formate. For the first time, our device employs a nanostructured titanium nitride (TiN) support for the immobilization of a formate dehydrogenase (FDH) enzyme. The hierarchical TiN nanostructured support exhibits high surface area and wide pore size distribution, achieving high catalytic loading, and is characterized by higher conductivity than other oxide-based supports employed for FDHs immobilization. We select the oxygen-tolerant FDH from Thiobacillus sp. KNK65MA (TsFDH) as enzymatic catalyst, which selectively reduces CO2 to formate. We identify an optimal TiN morphology for the enzyme immobilisation through enzymatic assay, reaching a catalyst loading of 59 μg cm−2 of specifically-adsorbed TsFDH and achieving a complete saturation of the anchoring sites available on the surface. We evaluate the electrochemical CO2 reduction performance of the TiN/TsFDH system, achieving a remarkable HCOO− Faradaic efficiency up to 76 %, a maximum formate yield of 44.1 μmol mg−1FDH h−1 and high stability. Our results show the technological feasibility of BES devices employing novel, nanostructured TiN-based supports, representing an important step in the optimization of these devices

Enantioselective synthesis of a key "A-ring" intermediate for the preparation of 1alpha-fluoro vitamin D3 analogues.

1Alpha-fluoro A-ring dienol 2, a useful building block for the preparation of fluorinated vitamin D3 analogues, was synthesized in eight steps from 4-{[tert-butyldimethylsilyl]oxy}cyclohexanone. The most distinctive synthetic development to emerge from this new synthesis is an unprecedented substrate-controlled diastereoselective fluorodesilylation of an advanced dienylsilane intermediate. This is the first enantioselective route to compound 2 relying on the use of an electrophilic fluorinating reagent

Cantiere di studio e restauro del lapidario di Palazzo Ancarano, sede della Soprintendenza per i Beni Archeologici dell’Emilia Romagna

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Prove sul modello fisico del manufatto regolatore della cassa di espansione del torrente Parma

AIPO Informa Anno IV Volume 1-2 200

Organocatalyzed enantioselective fluorocyclizations.

Enantioenriched fluorinated heterocycles can be prepared through fluorocyclizations of prochiral indoles (see scheme; Ts=tosyl, Bn=benzyl, Boc=tert-butoxycarbonyl). More than twenty examples for this cascade fluorination-cyclization, which is catalyzed by cinchona alkaloids and employs N-fluorobenzenesulfonimide as the electrophilic fluorine source have been explored, and an unprecedented catalytic asymmetric difluorocyclization has also been identified

Collecting a multi-disciplinary field dataset to model the interactions between a flood control reservoir and the underlying porous aquifer

Eos Trans. AGU| 89(53)| Fall Meet. Suppl.| Abstract H41A-0829