Ultrasound velocity test to decay evaluation on decorative stone after different artificial ageing treatments

Ultrasound propagation velocity depends on several physical properties, for instance density, porosity and textural discontinuities within stones. These properties are strongly influenced by state of conservation of materials and their modification can be considered decay markers; therefore, ultrasound velocity measurement represents a non-destructive technique to evaluate the decay underway on employed stone. In this study, samples of the Avorio variety, an Apulian limestones, were processed to artificial ageing treatments, in particular thermal shocks, extreme thermal exposure at high temperatures between 200 and 600C, and cycles of immersion of rock samples into saline solution alternating with drying phases in muffle furnace. Effects of induced deterioration were examined by comparing p-wave ultrasound velocity values, visual appearance and mass loss with water absorption values and capillarity test results. This research suggests first that the ultrasound velocity test can be considered a valuable non-invasive technique to assess the state of decay of decorative and building stones. Furthermore, in order to simulate dangerous and extreme environmental conditions and study their influence on the stone decay patterns, new considerations and suggestions about ageing test and procedures were proposed

Glazed sgraffito ware from Torre Alemanna (Foggia, fifteenth to sixteenth century A.D.): technological aspects of a local production

The archaeometric investigation of 46 potsherds of “Torre Alemanna type” pottery aimed to define a compositional refer- ence group and to understand the technological characteristics of its production. Principal component analysis applied to bulk chemical data (XRF) of the ceramic body showed a strong compositional homogeneity. Their comparison with local clays and 6 fragments of bricks sampled from the ceramic kiln, on the one hand, revealed the use of alluvial clays as raw material and, on the other hand, proved their fractionation for the production of pottery. The mineralogical assemblages detected by X-ray powder diffraction analysis inferred maximum firing temperatures between 750 and 1000 °C for the ceramic body. Polarising optical microscopy and scanning electron microscopy with energy dispersive spectroscopy (SEM–EDS) investigations on coating revealed the presence of quartz-rich white engobe covered with a high lead transparent glaze. The polychromatic decoration was analysed by colorimetry and EDS to compare the colour characteristics through all the pot- sherds. A temperature range between 780 and 950 °C of liquidus temperatures was inferred from the ternary phase diagram of PbO-Al2O3-SiO2 system. Overlap of temperature ranges for sintering of the ceramic body and maturing glaze points to a single firing of the Torre Alemanna type ware. The results obtained define the reference compositional group and technol- ogy of the Torre Alemanna type ware, already attested in several archaeological contexts of southern Italy, and showed a technological continuity with the past about the use of local carbonate-rich clays to produce fine pottery

SiLiBA: Building the geological chert lithotheque

Lithotheques collect and exhibit raw material used by human communities for the manufacturing of objects during the Prehistory and represents an important tool of their knowledge. These collections are essential in the procuring and provenance study of archaeological lithic industries. This paper aims, firstly, to introduce SiLiBA, the lithotheque of the Earth and Geoenvironmental Sciences Department of the University of Bari Aldo Moro (Italy), as reference collection in the archaeological field studies, and secondly to propose guidelines and rules to build a lithotheque. The collection consists of about 900 pieces of geological cherts, which are the result of an expanded collecting action of primary and secondary cherts across Italy (Apulia, Basilicata, Sicily), Croatia, and Switzerland, belonging to formations from the Cretaceous to the Quaternary Period. All the chert samples were described according to the non-destructive multiparametric protocol for chert investigation (NM-PCI), providing a modular dataset of binary, ordinal and continuous variables which integrates petrographycal, micropaleontological, chemical and physical data. Such results were summarized in suitable reports, with also geographic coordinates, geological description and photographic documentation, in a digital database, which will be soon online. Cherts are grouped in 37 suitable boxes, following geographic hierarchical organisation and reporting informative labels. Some representative samples are exposed in the Earth Sciences Museum of the same University. Furthermore, the lithotheque is equipped by a dedicated laboratory which includes optical microscopes, a glossmeter and a spectrophotocolorimeter. The promotion in the last years was guaranteed by dissemination activities for educational and academic communities, including an interactive laboratory of experimental archaeology

Cystic echinococcosis in wild boars (Sus scrofa) from southern Italy: Epidemiological survey and molecular characterization.

Cystic Echinococcosis (CE) caused by Echinococcus granulosus sensu lato (s.l.) is one of the most important parasitic zoonotic diseases in the world and it represents an important public health and socio-economic concern. In the Mediterranean basin, CE is widespread and it is endemic in Italy, with major prevalence in southern areas. Several studies have investigated CE in domestic pigs, however, such data in wild boars are scant. In the last decades the wild boar population in Italy has increased and this ungulate could play an important role in the spreading ofCEinthewild.Here wereporton theprevalenceandfertility rateofhydatid cystsinwildboarsthat were shot during two hunting seasons (2016–2017) in the Campania region of southern Italy. For each animal, a detailed inspection of the carcass and organs (lungs, liver and spleen) was performed and when cysts were found, their number, morphology and fertility were determined by visual and microscopic examination. Cysts were classified morphologically as fertile, sterile, caseous and calcified. Protoscoleces and germinal layers were collected from individual cysts and DNA was extracted to identify different strains/genotypes of E. granulosus s.l. Outofatotalof2108wildboars93(4.4%)werefoundpositiveforCE.Infectedanimalswere45malesand48 females, aged between 1 and 8 years. The average number of cysts per wild boar was 1.3 (min 1 - max 13). The total number of cysts collected was 123, of which 118 (95.9%) in the liver, 4 (3.3%) in the lungs and 1 (0.8%) in the spleen. Of all analyzed cysts, 70 (56.9%) were fertile and 53 (43.1%) sterile/acephalous. The presence of fertile cysts in 19.4% of CE-positive animals is noteworthy. Overall, molecular diagnosis showed 19 wild boars infected with the pig strain (G7)

Disease-Modifying Therapies and Coronavirus Disease 2019 Severity in Multiple Sclerosis

Objective: This study was undertaken to assess the impact of immunosuppressive and immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID-19) in people with multiple sclerosis (PwMS). Methods: We retrospectively collected data of PwMS with suspected or confirmed COVID-19. All the patients had complete follow-up to death or recovery. Severe COVID-19 was defined by a 3-level variable: mild disease not requiring hospitalization versus pneumonia or hospitalization versus intensive care unit (ICU) admission or death. We evaluated baseline characteristics and MS therapies associated with severe COVID-19 by multivariate and propensity score (PS)-weighted ordinal logistic models. Sensitivity analyses were run to confirm the results. Results: Of 844 PwMS with suspected (n = 565) or confirmed (n = 279) COVID-19, 13 (1.54%) died; 11 of them were in a progressive MS phase, and 8 were without any therapy. Thirty-eight (4.5%) were admitted to an ICU; 99 (11.7%) had radiologically documented pneumonia; 96 (11.4%) were hospitalized. After adjusting for region, age, sex, progressive MS course, Expanded Disability Status Scale, disease duration, body mass index, comorbidities, and recent methylprednisolone use, therapy with an anti-CD20 agent (ocrelizumab or rituximab) was significantly associated (odds ratio [OR] = 2.37, 95% confidence interval [CI] = 1.18-4.74, p = 0.015) with increased risk of severe COVID-19. Recent use (<1 month) of methylprednisolone was also associated with a worse outcome (OR = 5.24, 95% CI = 2.20-12.53, p = 0.001). Results were confirmed by the PS-weighted analysis and by all the sensitivity analyses. Interpretation: This study showed an acceptable level of safety of therapies with a broad array of mechanisms of action. However, some specific elements of risk emerged. These will need to be considered while the COVID-19 pandemic persists

COVID-19 Severity in Multiple Sclerosis: Putting Data Into Context

Background and objectives: It is unclear how multiple sclerosis (MS) affects the severity of COVID-19. The aim of this study is to compare COVID-19-related outcomes collected in an Italian cohort of patients with MS with the outcomes expected in the age- and sex-matched Italian population. Methods: Hospitalization, intensive care unit (ICU) admission, and death after COVID-19 diagnosis of 1,362 patients with MS were compared with the age- and sex-matched Italian population in a retrospective observational case-cohort study with population-based control. The observed vs the expected events were compared in the whole MS cohort and in different subgroups (higher risk: Expanded Disability Status Scale [EDSS] score > 3 or at least 1 comorbidity, lower risk: EDSS score ≤ 3 and no comorbidities) by the χ2 test, and the risk excess was quantified by risk ratios (RRs). Results: The risk of severe events was about twice the risk in the age- and sex-matched Italian population: RR = 2.12 for hospitalization (p < 0.001), RR = 2.19 for ICU admission (p < 0.001), and RR = 2.43 for death (p < 0.001). The excess of risk was confined to the higher-risk group (n = 553). In lower-risk patients (n = 809), the rate of events was close to that of the Italian age- and sex-matched population (RR = 1.12 for hospitalization, RR = 1.52 for ICU admission, and RR = 1.19 for death). In the lower-risk group, an increased hospitalization risk was detected in patients on anti-CD20 (RR = 3.03, p = 0.005), whereas a decrease was detected in patients on interferon (0 observed vs 4 expected events, p = 0.04). Discussion: Overall, the MS cohort had a risk of severe events that is twice the risk than the age- and sex-matched Italian population. This excess of risk is mainly explained by the EDSS score and comorbidities, whereas a residual increase of hospitalization risk was observed in patients on anti-CD20 therapies and a decrease in people on interferon