Memory Lane and Morality: How Childhood Memories Promote Prosocial Behavior

Four experiments demonstrated that recalling memories from one's own childhood lead people to experience feelings of moral purity and to behave prosocially. In Experiment 1, participants instructed to recall memories from their childhood were more likely to help the experimenter with a supplementary task than were participants in a control condition, and this effect was mediated by self-reported feelings of moral purity. In Experiment 2, the same manipulation increased the amount of money participants donated to a good cause, and self-reported feelings of moral purity mediated this relationship. In Experiment 3, participants who recalled childhood memories judged the ethically-questionable behavior of others more harshly, suggesting that childhood memories lead to altruistic punishment. Finally, in Experiment 4, compared to a control condition, both positively-valenced and negatively-valenced childhood memories led to higher empathic concern for a person in need, which, in turn increased intentions to help.Childhood, Ethics, Memories, Morality, Prosocial Behavior, Purity

Seismic reliability analysis of isolated deck bridges using friction pendulum devices

In this study, the seismic reliability of multi-span continuous deck bridges equipped with isolation friction pendulum (FP) devices is investigated. The relevant aleatory uncertainties associated to the sliding friction coefficient of the FP isolators and to the seismic inputs are considered. A six-degree-of-freedom model is established to reproduce the elastic behavior of the reinforced concrete (RC) pier, the stiff response of the deck supported by the isolation devices and the non-linear response of the FPS bearings which depends on the sliding velocity. Moreover, the RC abutment is assumed as infinitely rigid. For what concerns the seismic inputs, a group of natural seismic records having various characteristics is adopted and properly scaled to increasing levels of intensity. The random variability of the friction coefficient is modelled by suitable probabilistic distribution. Then, considering several bridges and isolator configurations, the fragility curves of the RC pier and of the isolator devices (FP) are determined. Finally, in agreement with the hazard curve of the specific site, the convolution integral is adopted to determine the seismic reliability curves in the performance domain

Does "Could" Lead to Good? Toward a Theory of Moral Insight

We introduce the construct of moral insight and study how it can be elicited when people face ethical dilemmas—challenging decisions that feature tradeoffs between competing and seemingly incompatible values. Moral insight consists of discovering solutions that move beyond selecting one conflicting ethical option over another. Moral insight encompasses both a cognitive process and a discernible output: it involves the realization that an ethical dilemma might be addressed other than by conceding one set of moral imperatives to meet another, and it involves the generation of solutions that allow competing objectives to be met. Across four studies, we find that moral insight is generated when individuals are prompted to consider the question "What could I do?" in place of their intuitive approach of considering "What should I do?" Together, these studies point toward a theory of moral insight and important practical implications

Phosphorylation meets nuclear import: a review

Phosphorylation is the most common and pleiotropic modification in biology, which plays a vital role in regulating and finely tuning a multitude of biological pathways. Transport across the nuclear envelope is also an essential cellular function and is intimately linked to many degeneration processes that lead to disease. It is therefore not surprising that phosphorylation of cargos trafficking between the cytoplasm and nucleus is emerging as an important step to regulate nuclear availability, which directly affects gene expression, cell growth and proliferation. However, the literature on phosphorylation of nucleocytoplasmic trafficking cargos is often confusing. Phosphorylation, and its mirror process dephosphorylation, has been shown to have opposite and often contradictory effects on the ability of cargos to be transported across the nuclear envelope. Without a clear connection between attachment of a phosphate moiety and biological response, it is difficult to fully understand and predict how phosphorylation regulates nucleocytoplasmic trafficking. In this review, we will recapitulate clue findings in the field and provide some general rules on how reversible phosphorylation can affect the nuclear-cytoplasmic localization of substrates. This is only now beginning to emerge as a key regulatory step in biology

The Pot Calling the Kettle Black: Distancing Response to Ethical Dissonance

Six studies demonstrate the "pot calling the kettle black" phenomenon whereby people are guilty of the very fault they identify in others. Recalling an undeniable ethical failure, people experience ethical dissonance between their moral values and their behavioral misconduct. Our findings indicate that to reduce ethical dissonance, individuals use a double-distancing mechanism. Using an overcompensating ethical code, they judge others more harshly and present themselves as more virtuous and ethical (Studies 1, 2, 3). We show this mechanism is exclusive for ethical dissonance and is not triggered by salience of ethicality (Study 4), general sense of personal failure, or ethically neutral cognitive dissonance (Study 5). Finally, it is characterized by some boundary conditions (Study 6). We discuss the theoretical contribution of this work to research on moral regulation and ethical behavior

Model uncertainty in non-linear numerical analyses of slender reinforced concrete members

The present study aims to characterize the epistemic uncertainty within the use of global non-linear numerical analyses (i.e., NLNAs) for design and assessment purposes of slender reinforced concrete (RC) members. The epistemic uncertainty associated to NLNAs may be represented by approximations and choices performed during the definition of a structural numerical model. In order to quantify epistemic uncertainty associated to a non-linear numerical simulation, the resistance model uncertainty random variable has to be characterized by means of the comparison between experimental and numerical results. With this aim, a set of experimental tests on slender RC columns known from the literature is considered. Then, the experimental results in terms of maximum axial load are compared to the outcomes achieved from NLNAs. Nine different modeling hypotheses are herein considered to characterize the resistance model uncertainty random variable. The probabilistic analysis of the results has been performed according to Bayesian approach accounting also for both the previous knowledge from the scientific literature and the influence of the experimental uncertainty on the estimation of the statistics of the resistance model uncertainty random variable. Finally, the resistance model uncertainty partial safety factor is evaluated in line with the global resistance format of fib Model Code for Concrete Structures 2010 with reference to new and existing RC structures