4,507 research outputs found
Reduction criterion for separability
We introduce a separability criterion based on the positive map Γ:ρ→(Tr ρ)-ρ, where ρ is a trace-class Hermitian operator. Any separable state is mapped by the tensor product of Γ and the identity into a non-negative operator, which provides a simple necessary condition for separability. This condition is generally not sufficient because it is vulnerable to the dilution of entanglement. In the special case where one subsystem is a quantum bit, Γ reduces to time reversal, so that this separability condition is equivalent to partial transposition. It is therefore also sufficient for 2×2 and 2×3 systems. Finally, a simple connection between this map for two qubits and complex conjugation in the “magic” basis [Phys. Rev. Lett. 78, 5022 (1997)] is displayed
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Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy.
Natural killer (NK) cells of the innate immune system are a key focus of research within the field of immuno-oncology based on their ability to recognize and eliminate malignant cells without prior sensitization or priming. However, barriers have arisen in the effective translation of NK cells to the clinic, in part because of critical species differences between mice and humans. Companion animals, especially dogs, are valuable species for overcoming many of these barriers, as dogs develop spontaneous tumors in the setting of an intact immune system, and the genetic and epigenetic factors that underlie oncogenesis appear to be similar between dogs and humans. Here, we summarize the current state of knowledge for dog NK cells, including cell surface marker phenotype, key NK genes and genetic regulation, similarities and differences of dog NK cells to other mammals, especially human and mouse, expression of canonical inhibitory and activating receptors, ex vivo expansion techniques, and current and future clinical applications. While dog NK cells are not as well described as those in humans and mice, the knowledge of the field is increasing and clinical applications in dogs can potentially advance the field of human NK biology and therapy. Better characterization is needed to truly understand the similarities and differences of dog NK cells with mouse and human. This will allow for the canine model to speed clinical translation of NK immunotherapy studies and overcome key barriers in the optimization of NK cancer immunotherapy, including trafficking, longevity, and maximal in vivo support
Black Hole Production at the Large Hadron Collider
Black hole production at the Large Hadron Collider (LHC) is an interesting
consequence of TeV-scale gravity models. The predicted values, or lower limits,
for the fundamental Planck scale and number of extra dimensions will depend
directly on the accuracy of the black hole production cross-section. We give a
range of lower limits on the fundamental Planck scale that could be obtained at
LHC energies. In addition, we examine the effects of parton electric charge on
black hole production using the trapped-surface approach of general relativity.
Accounting for electric charge of the partons could reduce the black hole
cross-section by one to four orders of magnitude at the LHC.Comment: CTP Symposium on Supersymmetry at LHC: Theoretical and Experimental
Perspectives at the British University in Egypt 11-14 March 200
Locally Advanced Spiroadenocarcinoma in the Regional Axilla of a Breast Cancer Patient: Hallmarks of Definitive Diagnosis and Management.
Eccrine spiroadenocarcinoma is an extremely rare malignant eccrine gland tumor which may masquerade as other more common malignancies such as poorly differentiated squamous carcinoma or metastatic breast cancer. We report a case of an ulcerated axillary skin lesion with bulky adenopathy in a 77 year-old female with a prior history of ipsilateral triple negative breast carcinoma. The clear transition of benign spiradenoma to malignant carcinoma was essential to establishing a definitive diagnosis and treatment plan
Microcanonical treatment of black hole decay at the Large Hadron Collider
This study of corrections to the canonical picture of black hole decay in
large extra dimensions examines the effects of back-reaction corrected and
microcanonical emission at the LHC. We provide statistical interpretations of
the different multiparticle number densities in terms of black hole decay to
standard model particles. Provided new heavy particles of mass near the
fundamental Planck scale are not discovered, differences between these
corrections and thermal decay will be insignificant at the LHC.Comment: small additions and clarifications, format for J. Phys.
Effecting Systemic Change: Critical Strategic Approaches for Social Inclusion
This thematic issue focuses on critical, insightful, and innovative strategic approaches to social inclusion through a change in social systems. Contributions propose effective and responsive approaches, principles, practices, and/or models for impactful systemic change towards meaningful and practical social inclusion in our institutions, communities, and societies, adopting a systemic view - a wide‐angle lens - to explore opportunities for transformation
Effect of charged partons on black hole production at the Large Hadron Collider
The cross section for black hole production in hadron colliders is calculated
using a factorization hypothesis in which the parton-level process is
integrated over the parton density functions of the protons. The mass, spin,
charge, colour, and finite size of the partons are usually ignored. We examine
the effects of parton electric charge on black hole production using the
trapped-surface approach of general relativity. Accounting for electric charge
of the partons could reduce the black hole cross section by one to four orders
of magnitude at the Large Hadron Collider. The cross section results are
sensitive to the Standard Model brane thickness. Lower limits on the amount of
energy trapped behind the event horizon in the collision of charged particles
are also calculated.Comment: corrected typo in figure 1b; added some clarification in 3 places; 21
pages, 9 figures, JHEP3 forma
Noncommutative geometry inspired black holes in higher dimensions at the LHC
When embedding models of noncommutative geometry inspired black holes into
the peridium of large extra dimensions, it is natural to relate the
noncommutativity scale to the higher-dimensional Planck scale. If the Planck
scale is of the order of a TeV, noncommutative geometry inspired black holes
could become accessible to experiments. In this paper, we present a detailed
phenomenological study of the production and decay of these black holes at the
Large Hadron Collider (LHC). Noncommutative inspired black holes are relatively
cold and can be well described by the microcanonical ensemble during their
entire decay. One of the main consequences of the model is the existence of a
black hole remnant. The mass of the black hole remnant increases with
decreasing mass scale associated with noncommutative and decreasing number of
dimensions. The experimental signatures could be quite different from previous
studies of black holes and remnants at the LHC since the mass of the remnant
could be well above the Planck scale. Although the black hole remnant can be
very heavy, and perhaps even charged, it could result in very little activity
in the central detectors of the LHC experiments, when compared to the usual
anticipated black hole signatures. If this type of noncommutative inspired
black hole can be produced and detected, it would result in an additional mass
threshold above the Planck scale at which new physics occurs.Comment: 21 pages, 7 figure
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