52 research outputs found

    The death and burial of the person with mental retardation

    Get PDF
    What does the death and burial of the person with mental retardation really mean to parents, friends, and to the reader? This paper is an attempt to answer this question by reviewing the literature regarding the emotions, feelings and reactions of the parents to the death of the person with mental retardation. It will attempt to present some pastoral guidelines for the clergy and all who work with people with mental retardation. It will attempt to provide some support for the parents who have lived the joy and the sorrow. This paper will not deal with the process of death itself, nor with the understanding of feelings, emotions, and reactions toward death in general of the person with mental retardation. It will not deal with the personal reactions of persons with mental retardation toward their own deaths. It will attempt to review the literature regarding the parents\u27 feelings and reactions to the birth of the child who is diagnosed as having some degree of mental retardation, especially to a moderate, severe or profound degree. It will review the literature regarding the chronic sorrow and mourning of the parents following the birth of the child with mental retardation. Literature regarding pre-death and the parents\u27 reactions to terminal illness in their child, as well as the treatment and care of the severely and profoundly handicapped child during this time, will be reviewed. The author will attempt to describe the secular, Jewish and Christian understandings of death. The funeral rite will be reviewed, especially as it relates to the Judeo-Christian tradition. From this review of the literature conclusions will be drawn to assist the parents, the clergy and the reader at the moment of the death and burial of the person with mental retardation

    The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

    Get PDF
    The frequency of antifungal resistance, particularly to the azole class of ergosterol biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected with resistant isolates are exceptionally low. Beyond modification of the drug target, our understanding of the molecular basis of azole resistance in the fungal pathogen Aspergillus fumigatus is limited. We reasoned that clinically relevant antifungal resistance could derive from transcriptional rewiring, promoting drug resistance without concomitant reductions in pathogenicity. Here we report a genome-wide annotation of transcriptional regulators in A. fumigatus and construction of a library of 484 transcription factor null mutants. We identify 12 regulators that have a demonstrable role in itraconazole susceptibility and show that loss of the negative cofactor 2 complex leads to resistance, not only to the azoles but also the salvage therapeutics amphotericin B and terbinafine without significantly affecting pathogenicity

    Lying, honor, and contradiction

    No full text

    Reflections on dysfunctional functioning in the political economy of paper

    No full text
    Comment on Hull, Matthew. 2012. Government of paper: The materiality of bureaucracy in urban Pakistan. Berkeley: University of California Press

    Commentary

    No full text
    The great German sociologist Max Weber used to refer to “the community of shared memory”, the Erinnerungsgemeinshaft. But what are we to understand by memory and the work of memory (not to mention forgetting and the work of forgetting)? These are questions whose relevance seems to grow: in historical and anthropological writing, in work on nationalism or identity, community and ethnicity. The politics of representation, iconography, material and symbolic space and the traces of pasts whose re..

    Recognizing Islam : An Anthropologist's Introduction

    No full text
    Londonviii, 287 p.; 22 c

    Recognizing Islam : religion and society in the modern Middle East/ Gilsenan

    No full text
    287 hal. ; 22 cm
    corecore