34 research outputs found
Hemodynamic and physical performance during maximal exercise in patients with an aortic bioprosthetic valve Comparison of stentless versus stented bioprostheses
AbstractOBJECTIVESThe objective of this study was to compare stentless bioprostheses with stented bioprostheses with regard to their hemodynamic behavior during exercise.BACKGROUNDStentless aortic bioprostheses have better hemodynamic performances at rest than stented bioprostheses, but very few comparisons were performed during exercise.METHODSThirty-eight patients with normally functioning stentless (n = 19) or stented (n = 19) bioprostheses were submitted to a maximal ramp upright bicycle exercise test. Valve effective orifice area and mean transvalvular pressure gradient at rest and during peak exercise were successfully measured using Doppler echocardiography in 30 of the 38 patients.RESULTSAt peak exercise, the mean gradient increased significantly less in stentless than in stented bioprostheses (+5 ± 3 vs. +12 ± 8 mm Hg; p = 0.002) despite similar increases in mean flow rates (+137 ± 58 vs. +125 ± 65 ml/s; p = 0.58); valve area also increased but with no significant difference between groups. Despite this hemodynamic difference, exercise capacity was not significantly different, but left ventricular (LV) mass and function were closer to normal in stentless bioprostheses. Overall, there was a strong inverse relation between the mean gradient during peak exercise and the indexed valve area at rest (r = 0.90).CONCLUSIONSHemodynamics during exercise are better in stentless than stented bioprostheses due to the larger resting indexed valve area of stentless bioprostheses. This is associated with beneficial effects with regard to LV mass and function. The relation found between the resting indexed valve area and the gradient during exercise can be used to project the hemodynamic behavior of these bioprostheses at the time of operation. It should thus be useful to select the optimal prosthesis given the patientâs body surface area and level of physical activity
Rehabilitation and release of orphaned Eurasian lynx (Lynx lynx) in Europe: Implications for management and conservation.
Rehabilitation of injured or immature individuals has become an increasingly used conservation and management tool. However, scientific evaluation of rehabilitations is rare, raising concern about post-release welfare as well as the cost-effectiveness of spending scarce financial resources. Over the past 20 years, events of juvenile Eurasian lynx presumably orphaned have been observed in many European lynx populations. To guide the management of orphaned lynx, we documented survival, rehabilitation and fate after the release and evaluated the potential relevance of lynx orphan rehabilitation for population management and conservation implications. Data on 320 orphaned lynx was collected from 1975 to 2022 from 13 countries and nine populations. The majority of orphaned lynx (55%) were taken to rehabilitation centres or other enclosures. A total of 66 orphans were released back to nature. The portion of rehabilitated lynx who survived at least one year after release was 0.66. Release location was the best predictor for their survival. Of the 66 released lynx, ten have reproduced at least once (8 females and 2 males). Conservation implications of rehabilitation programmes include managing genetic diversity in small, isolated populations and reintroducing species to historical habitats. The lynx is a perfect model species as most reintroduced populations in Central Europe show significantly lower observed heterozygosity than most of the autochthonous populations, indicating that reintroduction bottlenecks, isolation and post-release management have long-term consequences on the genetic composition of populations. The release of translocated orphans could be a valuable contribution to Eurasian lynx conservation in Europe. It is recommended to release orphans at the distribution edge or in the frame of reintroduction projects instead of a release in the core area of a population where it is not necessary from a demographic and genetic point of view. Rehabilitation programmes can have conservation implications that extend far beyond individual welfare benefits
User's perspectives of barriers and facilitators to implementing quality colonoscopy services in Canada: a study protocol
<p>Abstract</p> <p>Background</p> <p>Colorectal cancer (CRC) represents a serious and growing health problem in Canada. Colonoscopy is used for screening and diagnosis of symptomatic or high CRC risk individuals. Although a number of countries are now implementing quality colonoscopy services, knowledge synthesis of barriers and facilitators perceived by healthcare professionals and patients during implementation has not been carried out. In addition, the perspectives of various stakeholders towards the implementation of quality colonoscopy services and the need of an efficient organisation of such services have been reported in the literature but have not been synthesised yet. The present study aims to produce a comprehensive synthesis of actual knowledge on the barriers and facilitators perceived by all stakeholders to the implementation of quality colonoscopy services in Canada.</p> <p>Methods</p> <p>First, we will conduct a comprehensive review of the scientific literature and other published documentation on the barriers and facilitators to implementing quality colonoscopy services. Standardised literature searches and data extraction methods will be used. The quality of the studies and their relevance to informing decisions on colonoscopy services implementation will be assessed. For each group of users identified, barriers and facilitators will be categorised and compiled using narrative synthesis and meta-analytical techniques. The principle factors identified for each group of users will then be validated for its applicability to various Canadian contexts using the Delphi study method. Following this study, a set of strategies will be identified to inform decision makers involved in the implementation of quality colonoscopy services across Canadian jurisdictions.</p> <p>Discussion</p> <p>This study will be the first to systematically summarise the barriers and facilitators to implementation of quality colonoscopy services perceived by different groups and to consider the local contexts in order to ensure the applicability of this knowledge to the particular realities of various Canadian jurisdictions. Linkages with strategic partners and decision makers in the realisation of this project will favour the utilisation of its results to support strategies for implementing quality colonoscopy services and CRC screening programs in the Canadian health system.</p
The prolonged use of niclosamide as a molluscicide for the control of Schistosoma mansoni
Effect of humeral stem design on humeral position and range of motion in reverse shoulder arthroplasty
Gilles Jobin Final residency lecture - Collision between dance and physics
CERN, the Republic and Canton of Geneva, and the City of Geneva are delighted to invite you to the final public lecture about collisions between dance and physics by the first winner of Collide@CERN Geneva, the choreographer Gilles Jobin.
The event marks the end of his residency and will be held at the CERN Globe of Science and Innovation on 6th November at 1800.
Doors open at 17.30
Programme
18.00 - Opening address by Rolf-Dieter Heuer, CERN Director General, Ariane Koek, CERN Cultural Specialist, Sami Kanaan, Administrative Councilor in charge of the Department of Culture and Sport of the City of Geneva, and Charles Beer, Vice President of the State Council in charge of the Department of Education, Culture and Sport.
18.30 - Presentation by Gilles Jobin (Switzerland) of his residency experience at CERN with live demonstrations with his dancers
19.15 - Discussion on CERN as a Place of Collisions and Interventions between Dance and Physics with Gilles Jobin (Switzerland) and CERN scientists Maria Dimou (Greece) and Michael Doser (Austria)
Moderated by Ariane Koek, CERN cultural specialist
The audience will have the opportunity to ask questions
19.45 - Cocktail
Please note that the event will be mainly in English.
To make a reservation, please send an email to Collide@CERN Cordinator: [email protected]
Cuerpo e imagen en la nueva danza
Cuerpos sobre blanco es el resultado
de tres años de reflexión y debate
en torno a las propuestas artĂsticas
presentadas en Desviaciones. Se
recogen en Ă©l conferencias, mesas
redondas y encuentros celebrados
durante las ediciones de 1999, 2000 y 2001, a los que se añaden
ensayos y entrevistas realizadas en diferentes momentos y lugares.
El titulo alude a la decisiĂłn tomada por Blanca Calvo y La Ribot en
Desviaciones 2000 de transformar la sala Cuarta Pared, un teatro de
paredes negras, en un espacio blanco y abierto, haciéndose eco del
interés de numerosos creadores escénicos por situar sus trabajos en
galerĂas, salas de arte y otros lugares de exhibiciĂłn o bien en espacios
que remitieran al tipo de recepciĂłn propio de las artes visuales. A pesar
de ser muchos los artistas que en los Ășltimos años han confrontado
sus cuerpos con el blanco (Xavier LeRoy, Bobby Baker, Gary Stevens,
Miriam Gourfink, La Ribot, Ion Munduate, Cuqui Jerez y Olga Mesa...),
no debe entenderse esta opciĂłn como una tendencia, sino mĂĄs bien
como una coincidencia de intereses en un momento, que no excluye
otras propuestas como las de JerĂłme Bel, Raymund Hoghe o Philipe
Gehmacher, que juegan con otros recursos del espacio escénico