Estimation in a growth study with irregular measurement times

Between 1982 and 1988 a growth study was carried out at the Division of Pediatric Oncology of the University Hospital of Groningen. A special feature of the project was that sample sizes are small and that ages at entry may be very different. In addition the intended design was not fully complied with. This paper highlights some aspects of the statistical analysis which is based on (1) reference scores, (2) statistical procedures allowing for an irregular pattern of measurement times caused by missing data and shifted measurement times

A geometric proof of the Kochen-Specker no-go theorem

We give a short geometric proof of the Kochen-Specker no-go theorem for non-contextual hidden variables models. Note added to this version: I understand from Jan-Aake Larsson that the construction we give here actually contains the original Kochen-Specker construction as well as many others (Bell, Conway and Kochen, Schuette, perhaps also Peres).Comment: This paper appeared some years ago, before the author was aware of quant-ph. It is relevant to recent developments concerning Kochen-Specker theorem

EXPO-12: Development and validation of the Exposure to Violent Extremism Scale

Objective: This study details the development and validation of the 12-item Exposure to Violent Extremism Scale (EXPO-12). We aimed to undertake a transparent and robust process of scale development to present a tool to facilitate research on the relationship between exposure and violent extremism. / Method: First, we generated an initial item pool and evaluated items via expert feedback (n = 6) and a task designed to assess item comprehension (n = 13; Study 1). Second, we explored the underlying factor structure with exploratory factor analysis (EFA) and evaluated item characteristics with item response theory (IRT) in a representative sample of the U.K. population (n = 1, 509; Study 2). Finally, we sought to replicate the factor structure proposed by Study 2 via confirmatory factor analysis (CFA) and examined convergent validity with a related construct, violent extremist intentions (n = 1, 475; Study 3). / Results: Study 1 resulted in a preliminary pool of 40 items. Study 2 used EFA to establish a four-factor structure consisting of 21 items. IRT further reduced the item pool by evaluating differential item functioning, discrimination, and location parameters, resulting in EXPO-12. Study 3 replicated the factor structure proposed in Study 2 via CFA. EXPO-12 demonstrated good convergent validity with violent extremist intentions. / Conclusion: EXPO-12 is presented as a preliminarily validated measure of the concept, alongside its limitations. The scale’s main implication is as a tool to facilitate research to unpack the complexity and nuances of the relationship between exposure and violent extremism

Progress in thin film GaAs solar cells

Solar cells using polycrystalline films of gallium arsenid

Significant differences in incubation times in sheep infected with bovine spongiform encephalopathy result from variation at codon 141 in the PRNP gene

The susceptibility of sheep to prion infection is linked to variation in the PRNP gene, which encodes the prion protein. Common polymorphisms occur at codons 136, 154 and 171. Sheep which are homozygous for the A<sub>136</sub>R<sub>154</sub>Q<sub>171</sub> allele are the most susceptible to bovine spongiform encephalopathy (BSE). The effect of other polymorphisms on BSE susceptibility is unknown. We orally infected ARQ/ARQ Cheviot sheep with equal amounts of BSE brain homogenate and a range of incubation periods was observed. When we segregated sheep according to the amino acid (L or F) encoded at codon 141 of the PRNP gene, the shortest incubation period was observed in LL141 sheep, whilst incubation periods in FF<sub>141</sub> and LF<sub>141</sub> sheep were significantly longer. No statistically significant differences existed in the expression of total prion protein or the disease-associated isoform in BSE-infected sheep within each genotype subgroup. This suggested that the amino acid encoded at codon 141 probably affects incubation times through direct effects on protein misfolding rates

Robustness of Planar Fourier Capture Arrays to Colour Changes and Lost Pixels

Planar Fourier capture arrays (PFCAs) are optical sensors built entirely in standard microchip manufacturing flows. PFCAs are composed of ensembles of angle sensitive pixels (ASPs) that each report a single coefficient of the Fourier transform of the far-away scene. Here we characterize the performance of PFCAs under the following three non-optimal conditions. First, we show that PFCAs can operate while sensing light of a wavelength other than the design point. Second, if only a randomly-selected subset of 10% of the ASPs are functional, we can nonetheless reconstruct the entire far-away scene using compressed sensing. Third, if the wavelength of the imaged light is unknown, it can be inferred by demanding self-consistency of the outputs.Comment: 15 pages including cover page, 12 figures, associated with the 9th International Conference on Position Sensitive Detector

Propulsion Study for Small Transport Aircraft Technology (STAT)

Propulsion requirements were determined for 0.5 and 0.7 Mach aircraft. Sensitivity studies were conducted on both these aircraft to determine parametrically the influence of propulsion characteristics on aircraft size and direct operating cost (DOC). Candidate technology elements and design features were identified and parametric studies conducted to select the STAT advanced engine cycle. Trade off studies were conducted to determine those advanced technologies and design features that would offer a reduction in DOC for operation of the STAT engines. These features were incorporated in the two STAT engines. A benefit assessment was conducted comparing the STAT engines to current technology engines of the same power and to 1985 derivatives of the current technology engines. Research and development programs were recommended as part of an overall technology development plan to ensure that full commercial development of the STAT engines could be initiated in 1988

Fibrational induction meets effects

This paper provides several induction rules that can be used to prove properties of effectful data types. Our results are semantic in nature and build upon Hermida and Jacobs’ fibrational formulation of induction for polynomial data types and its extension to all inductive data types by Ghani, Johann, and Fumex. An effectful data type μ(TF) is built from a functor F that describes data, and a monad T that computes effects. Our main contribution is to derive induction rules that are generic over all functors F and monads T such that μ(TF) exists. Along the way, we also derive a principle of definition by structural recursion for effectful data types that is similarly generic. Our induction rule is also generic over the kinds of properties to be proved: like the work on which we build, we work in a general fibrational setting and so can accommodate very general notions of properties, rather than just those of particular syntactic forms. We give examples exploiting the generality of our results, and show how our results specialize to those in the literature, particularly those of Filinski and Støvring

Unique Mass Texture for Quarks and Leptons

Texture specific quark mass matrices which are hermitian and hierarchical are examined in detail . In the case of texture 6 zeros matrices, out of sixteen possibilities examined by us, none is able to fit the low energy data (LED), for example, $V_{us} = 0.2196 \pm 0.0023$, $V_{cb} = 0.0395 \pm 0.0017$, $\frac{V_{ub}}{V_{cb}} = 0.08 \pm 0.02$, $V_{td}$ lies in the range $0.004 - 0.013$ (PDG). Similarly none of the 32 texture 5 zeros mass matrices considered is able to reproduce LED. In particular, the latest data from LEP regarding $|V_{ub}|/|V_{cb}|(=0.093\pm0.016)$ rules out all of them. In the texture 4 zeros case, we find that there is a unique texture structure for $U$ and $D$ mass matrices which is able to fit the data.Comment: 12 pages, LaTeX,some changes in the references,minor changes in the text,to appear in Phys Rev D(Rapid communications