1,840 research outputs found

    A protocol for the development of Core Outcome Sets for effectiveness trials and clinical audits in Renal Cell Cancer (R-COS)

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    The data collection for the interview study is funded by NHS Grampian Endowments, and the costs of the interview transcriptions and eDelphi licences will be paid by the Arcobaleno Cancer Trust. Neither funder had any role in the design of the study. All other parts of the study are currently unfunded. The research team is not personally reimbursed for their time and efforts apart from research input by SD, which is financed by Swedish government funding of clinical research (ALF).Peer reviewedPublisher PD

    Performance of On-Line Learning Methods in Predicting Multiprocessor Memory Access Patterns

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    Shared memory multiprocessors require reconfigurable interconnection networks (INs) for scalability. These INs are reconfigured by an IN control unit. However, these INs are often plagued by undesirable reconfiguration time that is primarily due to control latency, the amount of time delay that the control unit takes to decide on a desired new IN configuration. To reduce control latency, a trainable prediction unit (PU) was devised and added to the IN controller. The PU's job is to anticipate and reduce control configuration time, the major component of the control latency. Three different on-line prediction techniques were tested to learn and predict repetitive memory access patterns for three typical parallel processing applications, the 2-D relaxation algorithm, matrix multiply and Fast Fourier Transform. The predictions were then used by a routing control algorithm to reduce control latency by configuring the IN to provide needed memory access paths before they were requested. Three prediction techniques were used and tested: 1). a Markov predictor, 2). a linear predictor and 3). a time delay neural network (TDNN) predictor. As expected, different predictors performed best on different applications, however, the TDNN produced the best overall results. (Also cross-referenced as UMIACS-TR-96-59

    Three-Year Trajectory of Teachers’ Fidelity to a Drug Prevention Curriculum

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    Little is known about the trajectories over time of classroom teachers’ fidelity to drug prevention curricula. Using the “Concerns-Based Adoption Model” (C-BAM) as a theoretical framework, we hypothesized that teachers’ fidelity would improve with repetition. Participants comprised 23 middle school teachers who videotaped their administration of three entire iterations of the All Stars curriculum. Investigators coded two key curriculum lessons, specifically assessing the proportion of activities of each lesson teachers attempted and whether they omitted, added, or changed prescribed content, or delivered it using new methods. Study findings provided only partial support for the C-BAM model. Considerable variability in teachers’ performance over time was noted, suggesting that their progression over time may be nonlinear and dynamic, and quite possibly a function of their classroom and school contexts. There was also evidence that, by their third iteration of All Stars, teachers tended to regress toward the baseline mean. That is, the implementation quality of those that started out with high levels of fidelity tended to degrade, while those that started out with very low fidelity to the curriculum tended to improve. Study findings suggest the need for ongoing training and technical assistance, as well as “just in time” messages delivered electronically; but it is also possible that some prevention curricula may impose unrealistic expectations or burdens on teachers’ abilities and classroom time

    Enhanced C2_2H2_2 absorption within Jupiter's southern auroral oval from Juno UVS observations

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    Reflected sunlight observations from the Ultraviolet Spectrograph (UVS) on the Juno spacecraft were used to study the distribution of acetylene (C2_2H2_2) at Jupiter's south pole. We find that the shape of the C2_2H2_2 absorption feature varies significantly across the polar region, and this can be used to infer spatial variability in the C2_2H2_2 abundance. There is a localized region of enhanced C2_2H2_2 absorption which coincides with the location of Jupiter's southern polar aurora; the C2_2H2_2 abundance poleward of the auroral oval is a factor of 3 higher than adjacent quiescent, non-auroral longitudes. This builds on previous infrared studies which found enhanced C2_2H2_2 abundances within the northern auroral oval. This suggests that Jupiter's upper-atmosphere chemistry is being strongly influenced by the influx of charged auroral particles and demonstrates the necessity of developing ion-neutral photochemical models of Jupiter's polar regions.Comment: Accepted in JGR: Planet

    The balloon-borne large-aperture submillimeter telescope for polarimetry: BLAST-Pol

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    The Balloon-borne Large Aperture Submillimeter Telescope for Polarimetry (BLAST-Pol) is a suborbital mapping experiment designed to study the role played by magnetic fields in the star formation process. BLAST-Pol is the reconstructed BLAST telescope, with the addition of linear polarization capability. Using a 1.8 m Cassegrain telescope, BLAST-Pol images the sky onto a focal plane that consists of 280 bolometric detectors in three arrays, observing simultaneously at 250, 350, and 500 um. The diffraction-limited optical system provides a resolution of 30'' at 250 um. The polarimeter consists of photolithographic polarizing grids mounted in front of each bolometer/detector array. A rotating 4 K achromatic half-wave plate provides additional polarization modulation. With its unprecedented mapping speed and resolution, BLAST-Pol will produce three-color polarization maps for a large number of molecular clouds. The instrument provides a much needed bridge in spatial coverage between larger-scale, coarse resolution surveys and narrow field of view, and high resolution observations of substructure within molecular cloud cores. The first science flight will be from McMurdo Station, Antarctica in December 2010.Comment: 14 pages, 9 figures Submitted to SPIE Astronomical Telescopes and Instrumentation Conference 201

    Possible Transient Luminous Events observed in Jupiter's upper atmosphere

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    11 transient bright flashes were detected in Jupiter's atmosphere using the UVS instrument on the Juno spacecraft. These bright flashes are only observed in a single spin of the spacecraft and their brightness decays exponentially with time, with a duration of ~1.4 ms. The spectra are dominated by H2 Lyman band emission and based on the level of atmospheric absorption, we estimate a source altitude of 260 km above the 1-bar level. Based on these characteristics, we suggest that these are observations of Transient Luminous Events (TLEs) in Jupiter's upper atmosphere. In particular, we suggest that these are elves, sprites or sprite halos, three types of TLEs that occur in the Earth's upper atmosphere in response to tropospheric lightning strikes. This is supported by visible light imaging, which shows cloud features typical of lightning source regions at the locations of several of the bright flashes. TLEs have previously only been observed on Earth, although theoretical and experimental work has predicted that they should also be present on Jupiter.Comment: Accepted in JGR: Planets. 28 pages, 8 figure
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