Analysis of hypersonic pressure and heat transfer tests on a flat plate with a flap and a delta wing with body, elevons, fins, and rudders Final report

Hypersonic boundary layer separation and flow field interference analysis during Dyna-Soar space glider testin

Turbulent transition in a truncated one-dimensional model for shear flow

We present a reduced model for the transition to turbulence in shear flow that is simple enough to admit a thorough numerical investigation while allowing spatio-temporal dynamics that are substantially more complex than those allowed in previous modal truncations. Our model allows a comparison of the dynamics resulting from initial perturbations that are localised in the spanwise direction with those resulting from sinusoidal perturbations. For spanwise-localised initial conditions the subcritical transition to a `turbulent' state (i) takes place more abruptly, with a boundary between laminar and `turbulent' flow that is appears to be much less `structured' and (ii) results in a spatiotemporally chaotic regime within which the lifetimes of spatiotemporally complicated transients are longer, and are even more sensitive to initial conditions. The minimum initial energy $E_0$ required for a spanwise-localised initial perturbation to excite a chaotic transient has a power-law scaling with Reynolds number $E_0 \sim Re^p$ with $p \approx -4.3$. The exponent $p$ depends only weakly on the width of the localised perturbation and is lower than that commonly observed in previous low-dimensional models where typically $p \approx -2$. The distributions of lifetimes of chaotic transients at fixed Reynolds number are found to be consistent with exponential distributions.Comment: 22 pages. 11 figures. To appear in Proc. Roy. Soc.

Mechanism of Reconnection on Kinetic Scales Based on Magnetospheric Multiscale Mission Observations

We examine the role that ions and electrons play in reconnection using observations from the Magnetospheric Multiscale (MMS) mission on kinetic ion and electron scales, which are much shorter than magnetohydrodynamic scales. This study reports observations with unprecedented high resolution that MMS provides for magnetic eld (7.8 ms) and plasma (30 ms for electrons and 150 ms for ions). We analyze and compare approaches to the magnetopause in 2016 November, to the electron diffusion region in the magnetotail in 2017 July followed by a current sheet crossing in 2018 July. Besides magnetic eld reversals, changes in the direction of the ow velocity, and ion and electron heating, MMS observed large uctuations in the electron ow speeds in the magnetotail. As expected from numerical simulations, we have veried that when the eld lines and plasma become decoupled a large reconnecting electric eld related to the Hall current (110 mV/m) is responsible for fast reconnection in the ion diffusion region. Although inertial accelerating forces remain moderate (12 mV/m), the electric elds resulting from the divergence of the full electron pressure tensor provide the main contribution to the generalized Ohms law at the neutral sheet (as large as 200 mV/m). In our view, this illustrates that when ions decouple electron physics dominates. The results obtained on kinetic scales may be useful for better understanding the physical mechanisms governing reconnection processes in various magnetized laboratory and space plasmas

A Systematic Review of the safety of non-TNF inhibitor biologic and targeted synthetic drugs in rheumatic disease in pregnancy

Introduction: Despite increasing evidence to support safe use of tumour necrosis factor inhibitors (TNFi) and other biologic disease modifying anti-rheumatic drugs (bDMARDs) during pre-conception/pregnancy, there remains a paucity of evidence regarding the safety and compatibility of other non-TNFi and novel targeted synthetic (ts)DMARDs during pre-conception/pregnancy. Therefore, we conducted a systematic review to determine the compatibility of these drugs in pre-conception, during pregnancy and post-partum period. // Method: Databases including; EMBASE, Pubmed (MEDLINE), and Cochrane were searched up to 23rd October 2020 to find relevant peer-reviewed papers, using keywords including; rheumatic disease, pregnancy, conception/pre-conception, lactation/breastfeeding, childhood and vaccination/infection, and commonly prescribed non-TNFi drugs and tsDMARDs. // Results: Our search yielded 1483 papers that were screened independently by two authors, and 109 full-text papers were eligible for final analysis. These studies reported 1291 maternal pregnancies exposed to non-TNFi bDMARDs and tsDMARDs with known outcomes, including 721 live births, 219 spontaneous miscarriages and 27 congenital abnormalities. Paternal exposures in 174 pregnancies had reassuring outcomes. A total of 48 breastfed infants were exposed to non-TNFi bDMARDs and no adverse events reported upon long-term follow-up. Fifteen infants exposed to bDMARDs received normal vaccination regimes, including live vaccines, and had normal developmental outcomes, without any complications or infections. // Conclusion: Overall, the findings are reassuring and do not suggest a cause for any major concerns or an increased risk of adverse pregnancy outcomes for maternal or paternal exposures to non-TNFi bDMARDs or tsDMARDs. There were no major concerns for breastfeeding exposures to non-TNFi bDMARDs

Pulse Profiles, Accretion Column Dips and a Flare in GX 1+4 During a Faint State

The Rossi X-ray Timing Explorer (RXTE) spacecraft observed the X-ray pulsar GX 1+4 for a period of 34 hours on July 19/20 1996. The source faded from an intensity of ~20 mCrab to a minimum of <~0.7 mCrab and then partially recovered towards the end of the observation. This extended minimum lasted ~40,000 seconds. Phase folded light curves at a barycentric rotation period of 124.36568 +/- 0.00020 seconds show that near the center of the extended minimum the source stopped pulsing in the traditional sense but retained a weak dip feature at the rotation period. Away from the extended minimum the dips are progressively narrower at higher energies and may be interpreted as obscurations or eclipses of the hot spot by the accretion column. The pulse profile changed from leading-edge bright before the extended minimum to trailing-edge bright after it. Data from the Burst and Transient Source Experiment (BATSE) show that a torque reversal occurred <10 days after our observation. Our data indicate that the observed rotation departs from a constant period with a Pdot/P value of ~-1.5% per year at a 4.5 sigma significance. We infer that we may have serendipitously obtained data, with high sensitivity and temporal resolution about the time of an accretion disk spin reversal. We also observed a rapid flare which had some precursor activity, close to the center of the extended minimum.Comment: 19 pages, 6 figures, accepted for publication in Astrophysical Journal (tentatively scheduled for vol. 529 #1, 20 Jan 2000

Positive-Operator-Valued Time Observable in Quantum Mechanics

We examine the longstanding problem of introducing a time observable in Quantum Mechanics; using the formalism of positive-operator-valued measures we show how to define such an observable in a natural way and we discuss some consequences.Comment: 13 pages, LaTeX, no figures. Some minor changes, expanded the bibliography (now it is bigger than the one in the published version), changed the title and the style for publication on the International Journal of Theoretical Physic

Lidar System Model for Use With Path Obscurants and Experimental Validation

When lidar pulses travel through a short path that includes a relatively high concentration of aerosols, scattering phenomena can alter the power and temporal properties of the pulses significantly, causing undesirable effects in the received pulse. In many applications the design of the lidar transmitter and receiver must consider adverse environmental aerosol conditions to ensure the desired performance. We present an analytical model of lidar system operation when the optical path includes aerosols for use in support of instrument design, simulations, and system evaluation. The model considers an optical path terminated with a solid object, although it can also be applied, with minor modifications, to cases where the expected backscatter occurs from nonsolid objects. The optical path aerosols are characterized by their attenuation and backscatter coefficients derived by the Mie theory from the concentration and particle size distribution of the aerosol. Other inputs include the lidar system parameters and instrument response function, and the model output is the time-resolved received pulse. The model is demonstrated and experimentally validated with military fog oil smoke for short ranges (several meters). The results are obtained with a lidar system operating at a wavelength of 0.905 μm within and outside the aerosol. The model goodness of fit is evaluated using the statistical coefficient of determination whose value ranged from 0.88 to 0.99 in this study