Conceptualisations of Public Mental Health: The Role of Primary Prevention and the Social Determinants of Mental Health

Background: Within the area of public mental health there is a lack of consensus regarding how best to deliver a preventative and population-level approach to mental health. There has been increased interest in how psychologists can contribute towards developing a public mental health approach that focuses on the prevention of mental health problems, as opposed to treatment. A study that explores how psychologists think about, and engage with, public mental health and prevention has not been carried out before. Aims: This study aimed to explore how practitioner psychologists understand the concept of mental health prevention, how this informs their practice, and how they engage with the evidence on the social determinants of mental health as part of this. Method: Eleven semi-structured interviews were conducted with clinical and community psychologists involved in the area of public health and prevention. Interview transcripts were analysed using thematic analysis. Results: Participants’ understanding and use of public mental health and prevention approaches were captured in five themes. A description of these themes and associated sub-themes is presented. Conclusion: The findings indicate that there are a range of understandings regarding the concept of mental health prevention and that this relates to beliefs and values about mental health and where change should occur. The psychologists in this study had employed a variety of skills, models and theories in their prevention work. Most participants felt that prevention ought to address the social determinants of poor mental health, and some had found ways to do this through multi-sector work and influencing key decision makers. The implications for the theory and practice of applied psychologists involved in prevention, and for decision making in public mental health are discussed

The geometry of sound rays in a wind

We survey the close relationship between sound and light rays and geometry. In the case where the medium is at rest, the geometry is the classical geometry of Riemann. In the case where the medium is moving, the more general geometry known as Finsler geometry is needed. We develop these geometries ab initio, with examples, and in particular show how sound rays in a stratified atmosphere with a wind can be mapped to a problem of circles and straight lines.Comment: Popular review article to appear in Contemporary Physic

Super Weyl Anomalies in the AdS/CFT Correspondence

Anomalies of N = (4,4) superconformal field theories coupled to a conformal supergravity background in two dimensions are computed by using the AdS/CFT correspondence. We find that Weyl, axial gauge and super Weyl transformations are anomalous, while general coordinate, local Lorentz, vector gauge and local super transformations are not. The coefficients of the anomalies show that the superconformal field theories have the central charge expected in the AdS/CFT correspondence.Comment: 16 pages, LaTeX, references added and typos correcte

Isometric Embedding of BPS Branes in Flat Spaces with Two Times

We show how non-near horizon p-brane theories can be obtained from two embedding constraints in a flat higher dimensional space with 2 time directions. In particular this includes the construction of D3 branes from a flat 12-dimensional action, and M2 and M5 branes from 13 dimensions. The worldvolume actions are determined by constant forms in the higher dimension, reduced to the usual expressions by Lagrange multipliers. The formulation affords insight in the global aspects of the spacetime geometries and makes contact with recent work on two-time physics.Comment: 29 pages, 10 figures, Latex using epsf.sty and here.sty; v2: reference added and some small correction

The Cardy-Verlinde formula and entropy of Topological Reissner-Nordstr\"om black holes in de Sitter spaces

In this paper we discuss the question of whether the entropy of cosmological horizon in Topological Reissner-Nordstr\"om- de Sitter spaces can be described by the Cardy-Verlinde formula, which is supposed to be an entropy formula of conformal field theory in any dimension. Furthermore, we find that the entropy of black hole horizon can also be rewritten in terms of the Cardy-Verlinde formula for these black holes in de Sitter spaces, if we use the definition due to Abbott and Deser for conserved charges in asymptotically de Sitter spaces. Our result is in favour of the dS/CFT correspondence.Comment: 6 pages, accepted for publication in IJMP

Dilaton black holes in grand canonical ensemble near the extreme state

Dilaton black holes with a pure electric charge are considered in a framework of a grand canonical ensemble near the extreme state. It is shown that there exists such a subset of boundary data that the Hawking temperature smoothly goes to zero to an infinite value of a horizon radius but the horizon area and entropy are finite and differ from zero. In string theory the existence of a horizon in the extreme limit is due to the finiteness of a system only.Comment: 8 pages, RevTex 3.0. Presentation improved, discussion on metrics in string theory simplified. To be published in Phys.Rev.

Bohm and Einstein-Sasaki Metrics, Black Holes and Cosmological Event Horizons

We study physical applications of the Bohm metrics, which are infinite sequences of inhomogeneous Einstein metrics on spheres and products of spheres of dimension 5 <= d <= 9. We prove that all the Bohm metrics on S^3 x S^2 and S^3 x S^3 have negative eigenvalue modes of the Lichnerowicz operator and by numerical methods we establish that Bohm metrics on S^5 have negative eigenvalues too. We argue that all the Bohm metrics will have negative modes. These results imply that higher-dimensional black-hole spacetimes where the Bohm metric replaces the usual round sphere metric are classically unstable. We also show that the stability criterion for Freund-Rubin solutions is the same as for black-hole stability, and hence such solutions using Bohm metrics will also be unstable. We consider possible endpoints of the instabilities, and show that all Einstein-Sasaki manifolds give stable solutions. We show how Wick rotation of Bohm metrics gives spacetimes that provide counterexamples to a strict form of the Cosmic Baldness conjecture, but they are still consistent with the intuition behind the cosmic No-Hair conjectures. We show how the Lorentzian metrics may be created ``from nothing'' in a no-boundary setting. We argue that Lorentzian Bohm metrics are unstable to decay to de Sitter spacetime. We also argue that noncompact versions of the Bohm metrics have infinitely many negative Lichernowicz modes, and we conjecture a general relation between Lichnerowicz eigenvalues and non-uniqueness of the Dirichlet problem for Einstein's equations.Comment: 53 pages, 11 figure

Author response: Effects of orthostatic hypotension on cognition in Parkinson disease

OBJECTIVE: To investigate the relation between orthostatic hypotension (OH) and posture-mediated cognitive impairment in persons with Parkinson's disease (PD) without dementia. METHODS: There were 55 participants: 37 non-demented individuals with idiopathic PD, including 18 with OH (PDOH), and 19 without (PDWOH), and18 control participants (C). All participants completed neuropsychological tests in the supine and in the upright tilted position. Blood pressure was assessed in each posture using a standardized oscillometric cuff at the right brachial artery. RESULTS: The two PD groups performed similarly while supine, with a profile notable for executive dysfunction consisting of deficits in sustained attention, response inhibition, and semantic verbal fluency, as well as reduced verbal memory encoding and retention. When upright, these deficits were exacerbated and broadened to include additional cognitive functions in the PDOH group: deficits in phonemic verbal fluency, psychomotor speed, and both basic and complex aspects of auditory working memory. When group-specific supine scores were used as baseline anchors, both PD groups showed cognitive changes following tilt, though the PDOH group had a wider range of deficits in the executive functioning and memory domains and was the only group to show significant changes in visuospatial skills. CONCLUSIONS: Cognitive deficits in idiopathic PD have been widely reported, though assessments are typically performed in the supine position. While both PD groups had supine deficits that aligned with prior studies and clinical findings, we demonstrated that those with PD and orthostatic hypotension had transient, posture-mediated changes in excess of those found in PD without autonomic failure. These observed changes suggest an acute, reversible effect, and as orthostatic hypotension is a significant comorbid factor in PD, an independent target for clinical intervention. Further understanding of the effects of autonomic failure on cognition in other disorders is desirable, particularly in the context of neuroimaging studies and clinical assessments where data are collected only in the supine or seated positions. Identification of a distinct neuropsychological profile in PD with autonomic failure also has implications for functional activities of daily living and overall quality of life.Accepted manuscrip

Effects of orthostatic hypotension on cognition in Parkinson's disease

OBJECTIVE: To investigate the relation between orthostatic hypotension (OH) and posture-mediated cognitive impairment in Parkinson disease (PD) using a cross-sectional and within-group design. METHODS: Individuals without dementia with idiopathic PD included 18 with OH (PDOH) and 19 without OH; 18 control participants were also included. Neuropsychological tests were conducted in supine and upright-tilted positions. Blood pressure was assessed in each posture. RESULTS: The PD groups performed similarly while supine, demonstrating executive dysfunction in sustained attention and response inhibition, and reduced semantic fluency and verbal memory (encoding and retention). Upright posture exacerbated and broadened these deficits in the PDOH group to include phonemic fluency, psychomotor speed, and auditory working memory. When group-specific supine scores were used as baseline anchors, both PD groups showed cognitive changes following tilt, with the PDOH group exhibiting a wider range of deficits in executive function and memory as well as significant changes in visuospatial function. CONCLUSIONS: Cognitive deficits in PD have been widely reported with assessments performed in the supine position, as seen in both our PD groups. Here we demonstrated that those with PDOH had transient, posture-mediated changes in excess of those found in PD without OH. These observed changes suggest an acute, reversible effect. Understanding the effects of OH due to autonomic failure on cognition is desirable, particularly as neuroimaging and clinical assessments collect data only in the supine or seated positions. Identification of a distinct neuropsychological profile in PD with OH has quality of life implications, and OH presents itself as a possible target for intervention in cognitive disturbance.Accepted manuscriptAccepted manuscrip

Production of antibacterial compounds using Bacillus spp. isolated from thermal springs in Saudi Arabia

Seventeen water samples were collected from four different thermal springs in Saudi Arabia. Microbiological assays were used to assess the antibacterial activities of bacterial colonies against antibiotic-resistant and susceptible-bacterial strains, and 16S rRNA gene sequencing was used to identify the genus and species of these antibiotic-producing bacteria. Chromatography and spectroscopy were used to separate the active compounds and help figuring out what their structures were. Four compounds were isolated using bacteria: N-acetyltryptamine (1), isovaleric acid (2), ethyl-4-ethoxybenzoate (3) and phenylacetic acid (4). Compounds 1, 2 and 4 were produced from Bacillus pumilus and 3 was from Bacillus licheniformis (AH-E1). The outcomes of the minimum inhibitory concentrations (MICs) showed that all pure compounds produced in this work had antibacterial activities against Gram-positive pathogens (between 128 mg/L and 512 mg/L compared to the control) and compound 2 had activity against E. coli