Quando la scienza brancola nel buio: accordo di collaborazione tra l’Istituto dei Ciechi “Opere riunite I. Florio – F. ed A. Salamone” di Palermo e il CNR IAS di Capo Granitola

La convenzione oggetto del presente rapporto nasce nel contesto delle complesse attività di EduLab, gruppo di divulgazione scientifica che,seppur già attivo dal2008, nasce ufficialmente nel 2015e mette insieme ricercatori di varie discipline che condividono la passione di divulgare la scienza e i risultati da essa prodotti nei propri ambiti di competenza.La comunicazione scientifica, molto sentita e ben strutturata all’interno dell’IAS (ex. IAMC), ha portato a numerosi risultati e ad un numero ragguardevole di progetti e programmi, ed è un’attività ormai talmente ben consolidata da diventare organica all’istituto e alle sue strategie. I prodotti sviluppati sono tanti e anche i successi ottenuti, quali premi sulle attività di divulgazione, la partecipazione ad Expo 2015 ed a numerose edizioni in ambito di manifestazioni nazionali quali: Festival della Scienza, Esperienza insegna, Notte della scienza e Notte dei ricercatori, Illuminiamo la scienza. Grazie ad un curriculum unico e complesso, il gruppo è stato il driver della nascita dell’Osservatorio della Biodiversità della Regione Sicilia, oggi riferimento regionale per la didattica e la divulgazione scientifica sul tema della biodiversità, visitato ad oggi da più di 500 classi di studenti siciliani. Le ricadute culturali, di visibilità, nonché di immagine per l’istituto sono tantissime

“How a good video can remove ‘barriers’ for a more inclusive science communication”

There is a burgeoning body of evidence suggesting that technology can enhance learning, and multiple studies have shown that videos represent a very effective tool in science engagement and education. In fact, video media can transform the complexities of science and nature into something more tangible and tractable (Dabylchuk et al., 2018). Documentaries can hence be powerful tools for learning, to raise awareness for important topics, and adding a scientific approach makes it possible to deepen knowledge about the world. According to Dale’s cone of experience (Fig. 1), people memorize 10% of what they read, 20% of what they hear, 30% of what they see and 50% of what they hear and see (Wiman and Mierhenry, 1969). These statistics seems to convey a very clear message: blind or visually impaired people are penalised in the learning compared to sighted ones. However, our experience in the area of inclusive science communication has led us to wonder: are we sure that sight is a fundamental means for learning? Or is it possible that sight is a predominant sense over others, and therefore it can even mislead or limit learning? To answer this question, we held an ad-hoc educational laboratory with the users of the “IstitutodeiCiechiOpereRiunite I. Florio – F. ed A. Salamone” of Palermo, with which we have established a convention on 29/01/2019. Specifically, we involved 20 users with different degrees of visual impairment, in the projection of three science videos, selected from those realised by the EDUlab divulgation group over the years. At the end of the video projection, users were asked to express their opinions and their personal interpretations of scientific issues, allowing us to understand what e how many information have been received and, above all, if sighted usersare really advantaged compared to the visually impaired ones

“Beaks and berries”: zoological laboratory (II) of the formative proposal of inclusive scientific divulgation

Searching a topic that help us about the implementation of an inclusive divulgation, aimed also at sensory disabilitiesusers, we have chosen birds as a key to connect different scientific issues (pollution, environmental changes, exploitation of resources) and create new knowledge in a heterogeneous auditorium, through the suggestions that the workshop lessons can infuse on the users, whether they are disabled or not. All this to bring them closer to thescientific contents to which they do not have easy access. In particular, the project aims to develop, deepen and consolidate, through communication and information, issues concerning the concept of biodiversity, in order to sensitize users to safeguard the species and habitats of our territory and make them as the main actors of scientific dissemination.Indeed, weestabilisheda convention between the “Istituto dei Ciechi Opere riunite I. Florio – F. ed A. Salamone” of Palermo and the “Consiglio Nazionale delle Ricerche - Istituto per lo studio degli impatti Antropici e Sostenibilità in ambiente marino” of Capo Granitola (TP). The main role of this convention is to bring disable people closer to these scientific subjects and make the contents of our laboratories as inclusive as possible.The project "The world of birds", developed from January to April 2019 is divided into three main themes, the second of which is the focus of this report: The bird alimentation

“For whom the Calandra tolls?”: zoological laboratory (III) of the formative proposal of inclusive scientific divulgation

Blind people, though not seeing the world, is nevertheless able to imagine it, activating mental processes different from those of the sighted. They can come in contact with the reality of the world and know it with appreciable effectiveness (Angeli F., 2012). It has been imagined that only the view was the capable sense of allowing the conception of space and its forms. Of course, it was the facts that showed, with increasing clarity, that the lack of sight does not prevent the mental construction of space. Although touch is generally regarded as the sight of the blind, it is important to understand how sight cannot be validly replaced by a single sense. To organize a good relationship with the surrounding reality, the person who does not see needs to activate the whole of their residual senses. In particular, the complementarity between touch and hearing makes us understand like the blind. The touch sense has a very small perceptive field and therefore proceeds bysuccession of spatial fragments, but also presents a very analytical capacity,refined and punctual. Hearing has a greatly extended perceptual field, whichallows the blind to have a broad overall spatial reference but offers insufficient information on the objects and on the particular characteristics of the surrounding space (Coppa M.M., 1997).We have therefore devised a playful-practical laboratory to allow a sensory disabilitypublic,with various degrees of blindness, to reach zoological and scientific contents and then re-connect to more general problems such as the numerous environmental emergencies of this decade. Thanks to a convention between the “IstitutodeiCiechiOpereriunite I. Florio – F. ed A. Salamone” of Palermo and the “Consiglio Nazionale delleRicerche - Istituto per lo studio degliimpattiAntropici e Sostenibilità in ambientemarino” of Capo Granitola (TP), we start with the project "The world of birds", developed from January to April 2019 and divided into three main themes. The third of which is the focus of this report: Nest and songs

“On the science’s wing”: zoological laboratory (I) of the formative proposal of inclusive scientific divulgation

The scientific divulgation work is increasingly like a facilitator task. In fact, in this work it is primary to transform the results and the notions of scientific research so that they became accessible to the public, understood as the largest possible number of people. However, this information flow turns out to be purely verbal, moreover with a language rich of visual references, that are inaccessible and incomprehensible for the user with sensory disabilities. Wehavethusestablished a convention between the “Istituto dei Ciechi Opere riunite I. Florio – F. ed A. Salamone” of Palermo and the “Consiglio Nazionale delle Ricerche - Istituto per lo studio degli impatti Antropici e Sostenibilità in ambiente marino” of Capo Granitola (TP). Wedeveloped a formative proposal that links the science world with sensory disabilities, proposing Birds as principal argument and the whole world connected to it. The birds appear as the key to connect to different scientific issues (pollution, environmental changes, exploitation of resources) to create new knowledge in the public, through the suggestions that the workshop lessons can give people, both disabled or not. All this in order to bring them closer to these subjects and make the contents of our laboratories as inclusive as possible. The project "The world of birds", developed from January to April 2019 is divided into three main themes, the first of which is the focus of this report: The bird plumage

Clinical Features, Cardiovascular Risk Profile, and Therapeutic Trajectories of Patients with Type 2 Diabetes Candidate for Oral Semaglutide Therapy in the Italian Specialist Care

Introduction: This study aimed to address therapeutic inertia in the management of type 2 diabetes (T2D) by investigating the potential of early treatment with oral semaglutide. Methods: A cross-sectional survey was conducted between October 2021 and April 2022 among specialists treating individuals with T2D. A scientific committee designed a data collection form covering demographics, cardiovascular risk, glucose control metrics, ongoing therapies, and physician judgments on treatment appropriateness. Participants completed anonymous patient questionnaires reflecting routine clinical encounters. The preferred therapeutic regimen for each patient was also identified. Results: The analysis was conducted on 4449 patients initiating oral semaglutide. The population had a relatively short disease duration (42%  60% of patients, and more often than sitagliptin or empagliflozin. Conclusion: The study supports the potential of early implementation of oral semaglutide as a strategy to overcome therapeutic inertia and enhance T2D management

Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage 653 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage 653 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage 653 CKD (eGFR < 60 mL/min/1.73 m2) or eGFR reduction > 30% from baseline was evaluated. Results: The mean estimated GFR was 98 \ub1 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR < 90 ml/min/m2 were independent risk factors for stage 653 CKD and renal function worsening. When compared to patients with eGFR > 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage 653 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening