10 research outputs found
The Effect of Optimally Timed Osteopathic Manipulative Treatment on Length of Hospital Stay in Moderate and Late Preterm Infants: Results from a RCT
Introduction. Little research has been conducted looking at the effects of osteopathic manipulative treatment (OMT) on preterm infants. Aim of the Study. This study hypothesized that osteopathic care is effective in reducing length of hospital stay and that early OMT produces the most pronounced benefit, compared to moderately early and late OMT. A secondary outcome was to estimate hospital cost savings by the use of OMT. Methods. 110 newborns ranging from 32- to 37-week gestation were randomized to receive either OMT or usual pediatric care. Early, moderately early, and late OMT were defined as <4, <9, and <14 days from birth, respectively. Result. Hospital stay was shorter in infants receiving late OMT (−2.03; 95% CI −3.15, −0.91; P<0.01) than controls. Subgroup analysis of infants receiving early and moderately early OMT resulted in shorter LOS (early OMT: −4.16; −6.05, −2.27; P<0.001; moderately early OMT: −3.12; −4.36, −1.89; P<0.001). Costs analysis showed that OMT significantly produced a net saving of €740 (−1309.54, −170.33; P=0.01) per newborn per LOS. Conclusions. This study shows evidence that the sooner OMT is provided, the shorter their hospital stay is. There is also a positive association of OMT with overall reduction in cost of care
Effect of osteopathic manipulative treatment on gastrointestinal function and length of stay of preterm infants: an exploratory study
Abstract Background Organizational improvement of neonatal intensive care units requires strict monitoring of preterm infants, including routine assessment of physiological functions of the gastrointestinal system and optimized procedures for the definition of appropriate discharge timing. Methods We conducted a prospective study on the effect of osteopathic manipulative treatment in a cohort of N = 350 consecutive premature infants admitted to a neonatal intensive care unit without any major complication between 2005 and 2008. In addition to ordinary care, N = 162 subjects received osteopathic treatment. Endpoints of the study were differences between study and control groups in terms of excessive length of stay and gastrointestinal symptoms, defined as the upper quartiles in the distribution of the overall population. Statistical analysis was based on crude and adjusted odds ratios from multivariate logistic regression. Results Baseline characteristics were evenly distributed across treated/control groups, except for the rate of infants unable to be oral fed at admission, significantly higher among those undergoing osteopathic care (p = .03). Osteopathic treatment was significantly associated with a reduced risk of an average daily occurrence of gut symptoms per subject above .44 (OR = 0.45; 0.26-0.74). Gestational age lower or equal to 32 weeks, birth weight lower or equal to 1700 grams and no milk consumption at admission were associated with higher rates of length of stay in the unit of at least 28 days, while osteopathic treatment significantly reduced such risk (OR = 0.22;0.09-0.51). Conclusions In a population of premature infants, osteopathic manipulative treatment showed to reduce a high occurrence of gastrointestinal symptoms and an excessive length of stay in the NICU. Randomized control studies are needed to generalize these results to a broad population of high risk newborns.</p
The Effect of Optimally Timed Osteopathic Manipulative Treatment on Length of Hospital Stay in Moderate and Late Preterm Infants: Results from a RCT
Introduction. Little research has been conducted looking at the effects of osteopathic manipulative treatment (OMT) on preterm infants. Aim of the Study. This study hypothesized that osteopathic care is effective in reducing length of hospital stay and that early OMT produces the most pronounced benefit, compared to moderately early and late OMT. A secondary outcome was to estimate hospital cost savings by the use of OMT. Methods. 110 newborns ranging from 32-to 37-week gestation were randomized to receive either OMT or usual pediatric care. Early, moderately early, and late OMT were defined as <4, <9, and <14 days from birth, respectively. Result. Hospital stay was shorter in infants receiving late OMT (−2.03; 95% CI −3.15, −0.91; < 0.01) than controls. Subgroup analysis of infants receiving early and moderately early OMT resulted in shorter LOS (early OMT: −4.16; −6.05, −2.27; < 0.001; moderately early OMT: −3.12; −4.36, −1.89; < 0.001). Costs analysis showed that OMT significantly produced a net saving of C740 (−1309.54, −170.33; = 0.01) per newborn per LOS. Conclusions. This study shows evidence that the sooner OMT is provided, the shorter their hospital stay is. There is also a positive association of OMT with overall reduction in cost of care
Cinématique intervertébrale et costo-vertébrale in vivo dans la mécanique respiratoire: Étude préliminaire de l’axe hélicoïdal et représentation anatomique du mouvement par modélisation
Contexte :le complexe articulaire costo-vertébral est décrit comme pouvant être impliqué tant dans la fonction respiratoire que dans la stabilité du rachis thoracique. D’un point de vue fonctionnel, le thorax a régulièrement été étudié pour comprendre la relation physiologique entre les mouvements musculo-squelettiques thoraciques et les échanges gazeux pulmonaires. Quelques études rapportent différentes donnéesin vitro, principalement sur le comportement mécanique en charge et la cinématique de la jonction costo-vertébrale (JCV). Actuellement il subsiste un réel manque de données in vivo concernant la cinématique costo-vertébrale tant pour des conditions physiologiques normales que dans des situations cliniques.Méthode :dans cette étude, des acquisitions tomodensitométriques ont été réalisées dans trois positions respiratoires différentes (Capacité pulmonaire totale, Capacité inspiratoire moyenne, Capacité résiduelle fonctionnelle). Les amplitudes de mouvement ont été obtenues par la méthode des OVP (Orientation Vector Position). La méthode de l’axe hélicoïdal moyen a permis d’obtenir une visualisation segmentaire de l’axe fonctionnel des JCV.Résultats :les données cinématiques ainsi qu’une représentation anatomique du mouvement ont été obtenues bilatéralement pour les JCV des sept premières paires de côtes. L’étude de l’axe hélicoïdal moyen montre des orientations variables selon le niveau considéré.Interprétation :cette étude présente une méthode originale d’analyse cinématique de la jonction costo-vertébrale en y ajoutant une représentation anatomique du mouvement ainsi que de l’axe fonctionnel. Une analyse sur un échantillon plus large est indispensable pour renforcer la pertinence de ces résultats préliminaires avant d’investiguer l’influence de différentes conditions cliniques sur la biomécanique du thorax.info:eu-repo/semantics/publishe
A Multicenter, Randomized, Controlled Trial of Osteopathic Manipulative Treatment on Preterms
<div><p>Background</p><p>Despite some preliminary evidence, it is still largely unknown whether osteopathic manipulative treatment improves preterm clinical outcomes.</p><p>Materials and Methods</p><p>The present multi-center randomized single blind parallel group clinical trial enrolled newborns who met the criteria for gestational age between 29 and 37 weeks, without any congenital complication from 3 different public neonatal intensive care units. Preterm infants were randomly assigned to usual prenatal care (control group) or osteopathic manipulative treatment (study group). The primary outcome was the mean difference in length of hospital stay between groups.</p><p>Results</p><p>A total of 695 newborns were randomly assigned to either the study group (n= 352) or the control group (n=343). A statistical significant difference was observed between the two groups for the primary outcome (13.8 and 17.5 days for the study and control group respectively, p<0.001, effect size: 0.31). Multivariate analysis showed a reduction of the length of stay of 3.9 days (95% CI -5.5 to -2.3, p<0.001). Furthermore, there were significant reductions with treatment as compared to usual care in cost (difference between study and control group: 1,586.01€; 95% CI 1,087.18 to 6,277.28; p<0.001) but not in daily weight gain. There were no complications associated to the intervention.</p><p>Conclusions</p><p>Osteopathic treatment reduced significantly the number of days of hospitalization and is cost-effective on a large cohort of preterm infants.</p></div
Description of the study population at the enrollment.
<p>RDS: respiratory distress syndrome. DRG: diagnosis related groups at discharge. PROM: premature rupture of membrane. Numbers are mean(sd). P value from t-test.</p><p>*n(%), p value from chi-square test.</p><p><sup>§</sup>complications were classified according to ICD-9 codes.</p><p><sup>§§</sup>pregnancy data were classified according to ICD-9 diagnosis codes.</p><p>**n(%), p value from Fisher exact test.</p><p>Description of the study population at the enrollment.</p
Relationship between LOS and GA by study group.
<p>Mean total and 95% CI length of hospital stay (LOS) measured in days per gestational age (GA) measured in weeks. Groups are: control (red) and OMT (cyan). A linear quadratic effect of LOS on GA is showed in both groups but the use of OMT significantly reduced LOS along different GAs (up to 36 weeks) compared to control group.</p
Results of multivariate linear regression for length of stay and weight gain.
<p>LOS = length of stay; OMT = osteopathic manipulative treatment.</p><p>Results of multivariate linear regression for length of stay and weight gain.</p