9 research outputs found
Gold-Catalyzed CâH Bond Functionalization of Metallocenes: Synthesis of Densely Functionalized Ferrocene Derivatives
Gold-Catalyzed CâH Bond Functionalization of Metallocenes: Synthesis of Densely Functionalized Ferrocene Derivatives
A convenient
process for the direct functionalization of ferrocene that exploits
the high electrophilic character of goldâvinyl carbenoids catalytically
generated from vinyldiazo compounds and gold complexes is reported.
This process takes place with complete regioselectivity (vinilogous
reactivity). The synthesis of the corresponding ruthenocene analogues
has also been achieved. Preliminary studies on the reactivity of these
new organometallic compounds seem to suggest that the presence of
the adjacent ferrocenyl group confers a specific reactivity on the
functionalized carbon chain manifested in the easy dry state aerobic
allylic oxidation
Reactivity of Stabilized Vinyl Diazo Derivatives toward Unsaturated Hydrocarbons: Regioselective Gold-Catalyzed Carbon?Carbon Bond Formation
ChemInform Abstract: Pyridine Activation via Copper(I)-Catalyzed Annulation Toward Indolizines
Direct Access to ÎČ-Oxodiazo Compounds by Copper(II)-Catalyzed Oxidative Rearrangement of Stabilized Vinyl Diazo Derivatives
The copper(II)-catalyzed reaction of alkenyldiazo compounds with iodosylbenzene leading to ÎČ-oxodiazo derivatives is reported. This process occurs via an unprecedented 1,2-shift of the diazoacetate function. A selection of the synthetic applications of a representative member of this new class of functionalized diazo derivatives in the regioselective synthesis of substituted 1,4-dicarbonyl compounds is also reported