Verrucous Squamous Cell Cancer of the Esophagus: A Case Report

Verrucous Cancer of the esophagus is basically a type of squamous cell carcinoma and is associated with a chronic inflammatory process in the lower esophagus usually secondary to gastro-esophageal reflux disease (GERD). Mostly it is a local disease process but sometimes it can invade distant structures also. We report a case is a 62-year-old female patient who presented with marked weight loss, anorexia, and difficulty to take solid food. On Upper GI endoscopy there was a warty appearing irregular mass at the mid to distal esophagus. Superficial multiple biopsies were taken but turned negative for malignancy and re-endoscopy after a few days with deep multiple biopsies revealed the diagnosis of verrucous carcinoma on histopathology. The patient was having multiple co-morbid conditions like hypertension, diabetes mellitus, and early nephropathy along with infiltration of malignancy in surrounding structures on CT scan chest. Therefore a decision was taken to place an esophageal stent by upper GI endoscopy followed by chemotherapy and radiotherapy by the oncology department. Patient symptoms were much relieved after 4 months of chemotherapy and radiotherapy and the patient is still on regular follow-up in medical OPD. Chronic inflammation due to gastritis and esophagitis is the main risk factor for verrucous carcinoma of the esophagus. Although surgery is the treatment of the choice for the local and early disease but as in our case disease was already spread palliative stenting followed by chemo-radiation is the best possible option that can be offered

Teaching communication skills and medical ethics to undergraduate medical student

Introduction: The purpose of this study was to improve communication skills and knowledge of bioethics of last year medical students doing clerkship and to evaluate the effectiveness of using workshops for this purpose from students’ point of view, in order to continue such programs in future. Methods: After Ethical approval for the study a two-day workshop on teaching effective communication skills and principles of medical ethics was planned and conducted by the department of Medical Education through multidisciplinary faculty of Foundation University Medical College, Pakistan. A total of 102 last year medical students participated in this workshop. The students were divided into 8 groups each containing 12 students. A team of pre trained facilitators for each group conducted the group activities. Teaching strategies including interactive discussions on basic principles of doctor-patient relationship, power point presentations, day to day case scenarios, video clips and presentations involving students in role plays were used. Pre and post workshop self evaluation proformas about knowledge and skills of communication and medical ethics were rated (0=none, 1=below average, 2=average, 3=above average, 4=very good, 5=excellent) by the students. Results: 89 out of 102 participants returned the proformas. A significant percentage of students (%82) showed improvement in their knowledge and skills of appreciating bioethical issues like valid informed consent, patient confidentiality, end of life issues and breaking bad news by rating as “very good” after participation in the workshop. More than %70 students recommended this activity for other students. Conclusion: Teaching through interactive workshops was found to be an effective method as reflected by students’ feedback. Therefore, the program will be continued in future

Disposal of syringes, needles, and lancets used by diabetic patients in Pakistan

Summary: Objective: To assess the use, handling and disposal of insulin injection equipment by diabetic patients in Pakistan. Methods: We conducted a cross-sectional study at diabetic clinics in five tertiary centers in Pakistan. All diabetic patients (type 1/type 2) who were on insulin for more than 1 month, were included. An Urdu (local language)-translated questionnaire was used to collect information on insulin administration equipment, the site and frequency of needle use, insulin syringe/pen/lancet disposal, sharing of needles and knowledge about diseases that are spread by sharing contaminated needles. Results: Of 375 patients, 58% were female. The mean (SD) duration of diabetes was 12.3 (7.3) years, and the duration of insulin use was 4.4 (4.3) years. The majority of the patients used syringes (88.3%) for insulin administration. Additionally, the majority of the patients disposed of used devices (syringes, 92%; pens, 75%; and lancets, 91%) in the household garbage collection bin. About half of the patients (n = 185) reported being educated by their physicians about the disposal of sharps. Those who were educated by a physician (adjusted odds ratio (adjOR): 0.36; 95%CI: 0.16–0.81) or could read/write English (adjOR: 0.32; 95%CI: 0.11–0.92) were less likely to dispose of syringes and needles in the household garbage. Conclusion: The common disposal of sharps in the household garbage has implications for disease transmission. Education on the safe disposal of sharps may improve the disposal practices. Keywords: Diabetes mellitus, Disposal practices, Insulin syringe, Lancets, Insulin pen