MESOPOROUS SILICA PARTICLES FOR DERMAL DRUG DELIVERY: A REVIEW

Mesoporous silica particles (MSP) have been reported to be applicable in diverse situations pertaining to the delivery of several drug molecules. MSP have established themselves in treating diseases with oral, dermal and parenteral modes of administration. Recently, dermal delivery using MSP have gained a considerable amount of interest owing to the increase in drug stability, permeation and ease of functionalization. MSP, in general, have a very high capability of delivering actives ranging from small molecules like drugs and amino acids to larger peptides, vaccines and antibodies. The applicability of MSP in achieving desired cosmetic and health-related outcomes depends on the careful tuning of their pore size, surface area, shape and overall physicochemical properties. This review provides comprehensive details of the recent developments in the fabrication of MSP, their characteristic features and, applications in dermal drug delivery. Studies on establishing the safety profile of MSP have also been summarized in the review

Restoring India's Terrestrial Ecosystems: Needs, Challenges, and Policy Recommendations

<p>This document is a product of the preparatory phase project of the National Mission on Biodiversity and Human Well-Being which was catalysed and supported by the Office of the Principal Scientific Advisor to the Government of India. It is the outcome of a series of stakeholder consultation meetings on ecological restoration of terrestrial landscapes and climate change in India. The insights from these meetings have been used to develop this document which highlights the challenges and best-practices in the restoration of terrestrial ecosystems, can serve as a guide for successful restoration of landscapes across different biomes of the Indian subcontinent, and help achieve India’s commitments to the Bonn Challenge and the goals set by India for biodiversity conservation, land restoration, climate mitigation and adaptation.</p&gt